site

Transport protein

...on . Changes in the conformation move the binding site to the opposite side of the protein. There are 3 types of transport proteins, uniporter , symporter / coporter , and antiporter , which facilitate different modes of transport....

Endoplasmic reticulum

...extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and other integral membrane proteins ) as well as proteins that are to be secreted or " exocytosed " from...

Endoplasmic reticulum

...extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and other integral membrane proteins ) as well as proteins that are to be secreted or " exocytosed " from...

Rudolf Steiner

... the second Goetheanum building began on the same site shortly before he died in 1925. He conceived it as an organic extension and metamorphosis of the first building, inspiring and pre-dating architects such as Le Corbusier , and Eero Saarinen 's Kennedy Airport ( 1962 ). Within the Society, Steine...

Endoplasmic reticulum

...extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and other integral membrane proteins ) as well as proteins that are to be secreted or " exocytosed " from...

RNA

...stretch of DNA-RNA hybrid is present at the active site of the enzyme. The synthesis continues until a termination sequence is reached. The resulting RNA molecule is the primary transcript . Modulation of the rate of initiation of RNA synthesis is one of the most important ways in which gene expression ...

Protein

...igand-protein binding is a property of the binding site known as affinity . Since proteins are involved ...odulation : When the binding of a ligand at one site on a protein affects the binding of ligand at another site. Covalent modulation : When the coval...

Promoter

...n Start Site (TSS) Approximately -35 A binding site for RNA polymerase RNA-polymerase I: transcribes genes encoding ribosomal RNA RNA-polymerase II: transcribes genes encoding mRNA and certain small nuclear RNAs RNA-polymerase III: transcribes genes encoding tRNAs and other small RNAs Genera...

Passive transport

... and the complex will then be bonded to a receptor site and moved through the cellular membrane. Bear in mind, however, that facilitated diffusion is a passive process, and the solutes still move down the concentration gradient. Filtration Main article: Filtration Filtration is movement of water ...

Operon

...an operator (the switch) a promoter (a binding site for the transcription enzyme ). The switch of a...r. In summary: The "operator" is a DNA binding site for a repressor; transcription of the structural genes takes place unless a repressor is bound to ...

Nutrition

... -- at global, regional and national levels". The site is available in English, French and Portuguese Disclaimer Please remember that Wikipedia is offered for informational use only. The information is in most cases not reviewed by professionals. You are advised to contact your doctor for health-r...

Neuroscience

...cience resources and news BrainMeta A community site Neuroanatomy & Neuropathology on the Internet High quality links Neuroscience. 2nd ed. by Purves et al (online textbook) Neuroscience for Kids NeuroWiki , a wiki website for Neuroscience related topics. All content (unless explici...

Malaria

...:387-8. PMID 12024215 External links WHO site on malaria CDC site on malaria Medline Plus site on malaria Malaria Vaccine Initiative Malaria. The UNICEF-U...

Liver

...the first trimester fetus , the liver is the main site of red blood cell production. By the 42nd week of gestation, the bone marrow has almost completely taken over that task. Producing an artifical organ or device capable of emulating most functions of the liver is outside the reach of science in ...

Lipase

...old Des 7:R141-6. Lowe, M. E. 1992. The catalytic site residues and interfacial binding of human pancreatic lipase. J Biol Chem 267:17069-73. Schrag, J. D., and M. Cygler. 1997. Lipases and alpha/beta hydrolase fold. Methods Enzymol 284:85-107. Spiegel, S., D. Foster, and R. Kolesnick. 1996. Signal tra...

Lambda phage

...phage λ takes place at a special attachment site in the bacterial genome, called att λ . The sequence of the att site is called att B and consists of the parts B-O-B', whereas thecomplementary sequence in the circul...

Kidney

...ing duct the medullary collecting duct . The site where the ascending loop of Henle touches the affe...taglomerular cells . Juxtaglomerular cells are the site of renin synthesis and secretion. Fluids become more concentrated along the tubules and ducts to...

Isozyme

...he enzyme, for example a long way from the active site then the mutation may be selectively neutral and subject to genetic drift . (3) In rare cases the mutation may result in an enzyme that is more efficient, or one that can catalyse a slightly different chemical reaction , in which case the muta...

Glycolipid

...nt outside the cell where it acts as a recognition site for specific chemicals as well as helping to maintain the stability of the membrane and attaching cells to one another to form tissues ....

Gene therapy

...rge sections of DNA and delivering it to the right site on the genome. Types of gene therapy In theory it is possible to transform either somatic cells (most cells of the body) or cells of the germline (such as stem cells , sperm and eggs ). All gene therapy so far in people has been directe...

Foot and mouth disease

...n contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral RNA and components of the protein coat are then synthesized in large quantities and assembled to form new viruses. After ...

Facilitated diffusion

...mpletely spans the membrane. It also has a binding site for the specific molecule (e.g., glucose ) or ion to be transported. After binding the molecule, the protein changes shape and carries the molecule across the membrane, where it is released. The protein then returns to its original shape, to wait fo...

Evolution

... requiring hard parts (like bone) and death near a site where sediments are being deposited, the fossil record only provides sparse and intermittent information about the evolution of life. Fossil evidence of early life is sparse before the evolution of organisms with hard body parts, such as shell, b...

Enzyme

...ites where the substrate (s) attach, and active site (s), where the amino acids perform the catalysis; ...the functionally related amino acids of the active site widely dispersed throughout the amino acid chain, with random mutation occurring anywhere. Enzym...

Enhancer

...ed to bind close to the transcription initiation site to affect its transcription, as some have been found to bind several hundreds of thousands base pairs upstream or downstream of the start site. Enhancers can also be found inside introns . An enhancer's orientation may even be reversed without af...

Endoplasmic reticulum

...extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and other integral membrane proteins ) as well as proteins that are to be secreted or " exocytosed " from...

Down syndrome

...me (Online book) Down Syndrome Information web site National Down Syndrome Society web site National Down Syndrome Congress web site The Down Syndrome Educational Trust web site Do...

Dialysis

...mplication, as are infections of the catheter exit site or "tunnel" (path from the peritoneum to the exit site). Because of this, patients are advised to take a number of precautions against infection. Step-by-step description of peritoneal dialysis (a CAPD exchange): The supplies and materials needed ...

Cooperativity

...ing sites . When substrate bonds to the active site of one enzymatic subunit, the rest of the subunits are stimulated and become active....

Competitive inhibitor

... inhibition , the molecule acts on the same active site as the normal enzyme substrate . The substrate molecules cannot enter the active site while the inhibitor is there, and inhibitors cannot enter the site when the substrate is there. Char...

Centromere

...e the kinetochore is assembled. Thus, it is the site where spindle fibers of the mitotic spindle at...o the chromosome during mitosis . It is also the site of the primary constriction visible in microscopy images of chromosomes. In most eukaryotes, the ce...

Cancer

...atic system, respectively). Radiation dose to each site depends on a number of factors, including the type of cancer and whether there are tissues and organs nearby that may be damaged by radiation. Clinical trials Clinical trials , also called experimental cancer treatment or research studies, tes...

Biology

...textbook. Biology Online : One person-maintained site with tutorials. The Tree of Life : A multi-authored, distributed Internet project containing information about phylogeny and biodiversity. The Journal of Biology : A small, but free, research journal The Public Library of Science: Biology ...

Antibody

...ht chain, which together shape the antigen binding site at the amino terminal end of the monomer. The two variable domains bind the antigens they are specific for and that elicited their production. The ability to bind a wide variety of foreign antigens arises from events know as somatic recombinatio...

Allostery

...n effector molecule at a so-called allosteric site . Changes that enhance activity are referred to as... collides with a molecule of substrate, the active site essentially forms a glove around its substrate. While such an induced fit converts a subunit from th...

Allostery

...n effector molecule at a so-called allosteric site . Changes that enhance activity are referred to as... collides with a molecule of substrate, the active site essentially forms a glove around its substrate. While such an induced fit converts a subunit from th...

Active transport

...ved by either altering the affinity of the binding site or altering the rate at which the protein changes conformations. Contents showTocToggle("show","hide") 1 Types 1.1 Primary 1.2 Secondary 1.2.1 Counter-transport 1.2.2 Co-transport 2 See also Types There are tw...

Active site

The active site of an enzyme is the binding site where catalysis occurs. The structure and chemical properties of the active site allow the recogn...