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Receptor in Biological Definition

Apoptosis

... neural tube: cells that receive Shh in a receptor in their membranes called Patched1 (Ptc1) survive ... absence of Shh, one of the ends of this same Ptc1 receptor (the carboxyl-terminal, inside the membrane) is ... These studies show how critical is the role of PS receptor (PSR) in the development of complex organisms ...

Immune system

... binds to a T "helper" cell's antigen receptor and to its CD28 receptor, which provides the ... / memory cell autoimmune disorders CD4 receptor /CD8 receptor / perforin / apoptosis /clonal selection ...

Ion channel

... Examples include the "nicotinic" Acetylcholine receptor , AMPA receptor and other neurotransmitter -gated channels. ... An example is the "muscarinic" Acetylcholine receptor Inward-rectifier K channels allow ...

Long-term potentiation

... one whose hippocampi were bathed in the NMDA receptor blocker APV , and the other acting as a control ... rats. This provided some evidence that the NMDA receptor — and thus LTP — was somehow involved ... learning. Doogie mice Enhanced NMDA receptor activity in the hippocampus has also been shown ...

Neurotransmitter

... It is important to appreciate that it is the receptor that dictates the neurotransmitter's effect. ... through neurotransmitter binding. Metabotropic receptor effects on ion channels are carried by second ... on whether an ionotropic or metabotropic receptor is the target of the molecule. Small molecule ...

Olfaction

... odor receptors. Humans have 347 functional odor receptor genes; the other genes have nonsense mutations . ... ), whereas some others cannot. Each olfactory receptor neuron in the nose expresses only one functional odor receptor. According to shape theory , each receptor detects a feature of the odor molecule . ...

Oncogene

... proteins that can become an oncogene: receptor tyrosine kinases that become constitutive (permanently) active like the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), vascular endothelial growth ...

Receptor

... receptor may refer to: In telecommunication , a receiver . In physiology , a sensory receptor is any structure which, on receiving ... nerve impulse . In biochemistry , a receptor is a protein molecule that receives and ...

Signal transduction

... Signal amplification at the transmembrane hormone receptor 5 Intracellular signal transduction ... cells to communicate across synapses , bind to receptor proteins in the membrane and open their ion ... a change in the shape or conformation of the receptor which occurs when the signal molecule "docks" or ...

Transmembrane receptor

... any integral membrane protein, a transmembrane receptor may be subdivided into three parts or domains . ... 3 The intracellular domain 4 Regulation of receptor activity 5 See also The ... The extracellular domain is the part of the receptor that sticks out of the membrane on the outside of ...

Morphogenesis

... cells are competent to respond to Hedgehog because they express the receptor protein Patched (blue in figure to left). Cells with activated Patch receptor make the Wingless protein (red in the figure). Wingless protein acts as ...

Morphogenesis

... cells are competent to respond to Hedgehog because they express the receptor protein Patched (blue in figure to left). Cells with activated Patch receptor make the Wingless protein (red in the figure). Wingless protein acts as ...

Transmembrane protein

... sequences . Examples Some cell adhesion proteins Some receptor proteins Glycophorin Insulin receptor GLUTI Integrin Cadherin See also : membrane topology , ...

B cell

... , where B cells are produced in all other vertebrates. The human body makes hundreds of different types of B cells, and each type has a unique receptor protein on its membrane that will bind to one particular antigen; at any one time in the human body millions of B cells are circulating in the blood ...

Cancer

... experience a reduced incidence of prostate cancer in comparison to men taking placebo pills. Daily use of tamoxifen , a selective estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developing breast cancer in high-risk women by about 50%. Cis-retinoic ...

Developmental biology

... signal transduction pathways that relay signals from outside of cells to the cell nucleus. Signal transduction pathways often involve receptors , receptor ligands and enzymes such as tampons. One key class of genes that are differentially regulated by transcription factors in different cell types are ...

Cell membrane

... envelopes the cell . It separates a cell's interior from its surroundings and controls what moves in and out. Cell surface membranes often contain receptor proteins and cell adhesion proteins . There are also other proteins with a variety of functions. These membrane proteins are important for the ...

Foot and mouth disease

... contain single-stranded RNA (ribonucleid acid, the viral genetic material). When such a virus comes in contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral RNA and ...

List of gene families

... (MHC) Related protein families Motor proteins Myosin Kinesin Dynein Signal transducing proteins receptor tyrosine kinases G-proteins Transporters ABC proteins ...

Lytic cycle

... Description The lytic cycle is a three-stage process. Infection When a virus infects a cell, it first binds with the cell membrane using receptor molecules on the virus's surface. The virus then injects its genetic material, which can be either DNA or RNA , into the cell. Growth The ...

Nutrition

... Important publications in nutrition References Bluher, Khan BP, Kahn CR, Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299 (5606): 572-4, Jan 24, 2003. The Times newspaper, January 31 2004 Could vitamins help delay the onset of ...

Passive transport

... and too large to fit through the membrane pores. Therefore, it will bind with its specific carrier proteins, and the complex will then be bonded to a receptor site and moved through the cellular membrane. Bear in mind, however, that facilitated diffusion is a passive process, and the solutes still move down ...

Cell membrane

... envelopes the cell . It separates a cell's interior from its surroundings and controls what moves in and out. Cell surface membranes often contain receptor proteins and cell adhesion proteins . There are also other proteins with a variety of functions. These membrane proteins are important for the ...

Second messenger

... They are synthesized or released by specific enzymatic reactions, usually as a result of an external signal that was received by a transmembrane receptor and pre-processed by other membrane-associated proteins . There are three basic types of second messenger molecules: Hydrophobic molecules ...
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