Actin
... Actin is a globular
protein that polymerize helicaly forming actin ... is important for the cells movement.
The
protein cofilin binds to ADP-actin units and promotes ... the minus end and prevents their reassembly. The
protein profilin reverses this effect by stimulating the ...
Affinity chromatography
... including nucleic acid purification,
protein purification from cell free extracts and ... for affinity binding (if the molecule is a
protein these are called fusion proteins ). Such tags ... if an organism is immunised against a GST-fusion
protein it will produce antibodies against the ...
Amino acid
... , that is modification after translation (
protein synthesis ). These modifications are often ... ethylene .
In addition to amino acids for
protein synthesis, there are other biologically important ... 115.13
6.30
1.95
10.64
Can disrupt
protein folding structures like α helix or ...
Anaphase
... to the centromeres . The point of contact is a
protein complex called the kinetochore, and these fibres ... kinases (M-Cdks). It also cleaves securin , a
protein that had been inhibiting separase . Separase then cleaves cohesin , the
protein responsible for holding sister chromatids ...
Antibody
... An antibody is a
protein used by the immune system to identify and ... they are globulins (in the γ-region of
protein electrophoresis ). They are synthesized and ... of immunoglobulin levels can be made by
protein electrophoresis . Here the plasma proteins are ...
Apoptosis
... For instance, misregulation of Hedgehog (Hgg)
protein signalling (see Development , below) has been ... becomes round (circular). This occurs because the
protein structures that conform the cytoskeleton are ... superfamily [10] . The Fas ligand (FasL, the
protein that binds to Fas and activates the Fas pathway) ...
Bioinformatics
... in the field include sequence alignment ,
protein structure alignment ,
protein structure prediction , prediction of gene ...
2.1 Gene expression analysis
2.2
protein expression analysis
2.3 Structure prediction ...
Biophysics
... of molecules. In addition things like solving a
protein structure or measuring the kinetics of single ... To include some: gene regulation , single
protein dynamics, bioenergetics, patch clamping , ... energy, biomolecular structures and dynamics,
protein folding, stochastic processes, surface dynamics.
...
BLAST
... are
Which bacterial species have a
protein that is related in lineage to a certain
protein whose amino-acid sequence I know?
Where does ... BLAST (blastp) : This program, given a
protein query, returns the most ...
Carbohydrate
... consuming energy , other forms being fat and
protein . Relatively complex carbohydrates are known as ... Oligosaccharides are found as common form of
protein posttranslational modification . ... can only utilize carbohydrates for energy, and
protein may not supply enough in many cases. The increase ...
Cell biology
... the cytoplasm . This process is also known as
protein biosynthesis or simply
protein translation . Some proteins, such as those to be ... ER and Golgi can be thought of as the "membrane
protein synthesis compartment" and the ...
Cell growth
... the normal size ( wee mutants). The Wee1
protein is a tyrosine kinase . It normally phosphorylates the Cdc2 cell cycle regulatory
protein on a tyrosine residue. This covalent ... may be regulated in part by dilution of Wee1
protein in cells as they grow larger.
Cell size ...
Cell metabolism
... catabolism
2.2 Fat catabolism
2.3
protein catabolism
3 See also
... of energy, and the building of membranes.
protein catabolism
Main article:
protein catabolism
...
Chromatin
... and consists of a complex of DNA and
protein in eukaryotic cells . It can be made visible ... of transcription and involves nuclear
protein exchange. The histones are mostly displaced, and ... cessation of transcription and involves nuclear
protein exchange. The histones are mostly displaced, and ...
Chromatography
... (either naturally present on the surface of the
protein or grafted with recombinant DNA techniques ) and ... in the purification of proteins (or better:
protein constructs). These constructs can be of fusion ... of these tags are usually removed and the pure
protein is obtained.
See also
Paper ...
Genetic code
... living cell , and is employed in the process of
protein synthesis . Nearly all living things use the ... related polymer RNA , which is better suited for
protein synthesis. This in turn is translated , by ... polypeptide ), which will then be folded into a
protein .
The gene sequence inscribed in DNA, and in ...
Collagen
... Collagen is the main
protein of connective tissue . It has great tensile ... form.
Collagen is the most abundant
protein in mammals .
Contents ... in mammals consists of inter-woven fibres of the
protein collagen. The collagen fibres consist of globular ...
Bioinformatics
... in the field include sequence alignment ,
protein structure alignment ,
protein structure prediction , prediction of gene ...
2.1 Gene expression analysis
2.2
protein expression analysis
2.3 Structure prediction ...
Cytoskeleton
... are so distant that they are not obvious from
protein sequence comparisons alone, the similarity of ... of the eukaryotic tubulin, was the first
protein of the prokaryotic cytoskeleton to be identified. ... During cell division , FtsZ is the first
protein to move to the division site, and is essential ...
Cytotoxic T cell
... by a MHC-antigen complex, T C cells release the
protein perforin , which forms pores in the target ... T C cells have present on the cell surface the
protein CD8 , which is attracted to portions of the Class ... activation. T C cells with CD8 surface
protein are called CD8+ T cells .
...
Disulfide bond
... S-S bond, the resulting molecule between the two
protein chains is called cystine . The figure below ... bacteria as a reversible switch that turns a
protein on or off when bacterial cells are exposed to ... links
Disulfide bonds and hair
protein disulfide bond formation in prokaryotes
...
DNA
... of nucleotides along a DNA strand defines a
protein , which an organism is liable to manufacture or ... sequence and the amino-acid sequence of the
protein is determined by simple cellular rules of ... of their genomes do double duty, encoding one
protein when read 5' to 3' along one strand, and a ...
Morphogenesis
... typically act through binding to specific
protein receptors . An important class of molecules ... genes are translated into proteins a Bicoid
protein gradient forms at the anterior end of the egg. Nanos
protein forms a gradient at the posterior end. The ...
Enzyme
... (in Greek en = in and zyme = blend) is a
protein , or
protein complex , that catalyzes a chemical reaction ... by structure. An enzyme can be a monomeric
protein made up of about hundred amino acids or more, ...
Facilitated diffusion
... across by transport proteins. The transport
protein involved is intrinsic, that is, it completely ... be transported. After binding the molecule, the
protein changes shape and carries the molecule across the membrane, where it is released. The
protein then returns to its original shape, to wait for ...
Flagellum
... flagellum
The filament is composed of the
protein flagellin and is a hollow tube 20 nanometers ... the hook and the basal body, passing through
protein rings in the cell's membranes that act as ... is driven by a rotary engine composed of
protein , located at the flagellum's anchor point on the ...
Cell membrane
... and structured bilayer of phospholipid and
protein molecules that envelopes the cell . It ... intrinsic proteins -- more at integral membrane
protein ). Glycoproteins have carbohydrates attached to ... and ionic molecules, which relies on a transport
protein to provide a channel or bind to specific ...
Gene
... of a gene encodes the chemical structure of a
protein . The genetic code determines the sequence of ... and organs . The instrumental roles of their
protein products range from mechanical support of the ... a gene specifies the amino-acid sequence of the
protein it encodes.
In most eukaryotic species, very ...
Genetic code
... living cell , and is employed in the process of
protein synthesis . Nearly all living things use the ... related polymer RNA , which is better suited for
protein synthesis. This in turn is translated , by ... polypeptide ), which will then be folded into a
protein .
The gene sequence inscribed in DNA, and in ...
Glycoprotein
... glycoprotein is a macromolecule composed of a
protein and a carbohydrate (a sugar ). The carbohydrate is usually attached to the
protein in a posttranslational modification , at either ... sialic acid .
The sugar group can assist in
protein folding or improve its stability. Glycoproteins ...
Hershey-Chase experiment
... virus that infects bacteria . It consists of a
protein coat that encloses the genetic material. When a ... T2 phages with radioactive 35 S-labeled
protein infected bacteria. In both experiments, bacteria ... DNA is the genetic material of phage and that
protein does not transmit genetic information.
Hershey ...
Heterozygote
... The effect of heterozygosity depends on the
protein product coded for by the gene in question. In ... other cases, the abnormal allele may produce no
protein at all. If the proteins are enzymes, the ... or disease. An abnormal gene that produces no
protein may not affect the person at all if the other ...
His-tag
... is a good ligand for nickel so the fusion
protein will bind to the column. The
protein can be eluted with a solution of imidazole .
... The his tag can also be used in detection of the
protein via anti-his-tag antibodies . This can be useful ...
Homeobox
... is about 180 base pairs long; it encodes a
protein domain (the homeodomain ) which can bind DNA. ... However, the specificity of a single homeodomain
protein is usually not enough to recognize only its ... .
Pit-1 homeobox-containing
protein bound to DNA
The homeobox genes were first ...
Insulin
... thousands of islets. They then isolated the
protein from these islets to produce what they called ... biologist Frederick Sanger . It was the first
protein the structure of which was completely determined. ... glucose
increase of DNA replication and
protein synthesis
modification of the activity of ...
Keratin
... view of stained keratin.
Keratin is a
protein used by numerous groups of animals as a structural element, and is a classic example of a fibrous
protein .
Keratin is a tough, insoluble
protein found in the outer layer of the skin of human ...
Kwashiorkor
... disorder caused by lack of nutrients, including
protein in the diet . The name is derived from one the ... starches and carbohydrates , and deficient in
protein (as is common in parts of the world where the ... can be treated by adding food energy and
protein to the diet; however, mortality can be as high as ...
Lambda phage
... Holliday structure and requires both the phage
protein int and the bacterial
protein IHF ( integration host factor ). Both int and ... the convention that genes are italicized, while
protein products are not, is followed, i.e. cI refers ...
Lipase
... found in nature, and represent distinct types of
protein folds [1] and catalytic mechanisms, most are ... from structure coordinates submitted to the
protein Data Bank from: Withers-Martinez, C., F. ... structure of a chimeric pancreatic lipase-related
protein 2 from guinea pig. Structure 4:1363-74.
...
Liver
... detoxification, glycogen storage and plasma
protein synthesis. It also produces bile which is ... V , VII , IX , and XI , as well as
protein C ,
protein S and antithrombin .
The liver neutralizes ...