Cancer
... through genetic and environmental factors ,
leading to aberrant growth regulation of cells.
Cell ... based on an excessive rate of cell division,
leading to a larger than usual number of cells. ... late 1990's cancer overtook heart disease as the
leading cause of death in the United Kingdom, and in 2002 ...
Lagging strand
... opposite side of the replication fork from the
leading strand . It goes from 5' to 3' (these numbers ... lagging strand is more complicated than of the
leading strand . On the
leading strand, Pol III "reads" the DNA and adds ...
Louis Pasteur
... the entry of microorganisms into the human body,
leading Joseph Lister to develop antiseptic methods ... was employed by many other physicians, eventually
leading to the eradication of the diseases typhus and ... Pasteur inaugurated the modern age of medicine ,
leading to an increase in the human life span in much of ...
Brain
... trauma, caused by automobile accidents or other blows to the skull, is a
leading cause of death. Often in these cases, more damage is caused by swelling, ... disease , are caused by the gradual death of individual neurons
leading to decrements in movement control, memory, and thinking abilities. ...
Diabetes mellitus
... high blood glucose causes changes in the shape of the lens in the eye,
leading to blurred vision and, perhaps, a visit to an optometrist . All ... panic. Consciousness can be altered, or even lost, in extreme cases,
leading to coma and/or seizures or even death and brain damage. Experienced ...
Liver
... disease causing the accumulation of iron in the body, eventually
leading to liver damage
Cancer of the liver (primary hepatocellular ... liver failure. Most transplants are done for chronic liver diseases
leading to cirrhosis , such as chronic hepatitis C, alcoholism, autoimmune ...
Nutrition
... knowledge, have called food processing into question.
Today's
leading nutritionists advise against the processing of food where possible, since ... on epidemiology:
"Analyses of data from the China studies ... is
leading to policy recommendations." He mentioned three:
"The greater the ...
Signal transduction
... cell.
Recognition of the hormone by the hormone receptor protein,
leading to a conformational change.
Relay and amplification of the signal ... undergoes a structural shift that affects the intracellular domain,
leading to further action. In this case the hormone itself does not pass through ...
Sociobiology
... which are descriptive, not prescriptive.
(MacDonald 1998) argues the
leading opponents of sociobiology and genetic behavior research self-identified as ... of Sociopathy, Mealey, 1995
Speak, Darwinists! Interviews with
leading sociobiologists.
...
Actin
... destabilizes the filament. ADP-actin dissociates from the minus end and the increase in ADP-actin stimulates the exchange of bound ADP for ATP,
leading to more ATP-actin units. This rapid turnover is important for the cells movement.
The protein cofilin binds to ADP-actin units and promotes their ...
Alga
... - cells forming a thallus with partial differentiation of tissues
In three lines even higher levels of organization have been reached,
leading to organisms with full tissue differentiation. These are the brown algae —some of which may reach 70 m in length ( kelps )—the red ...
Apoptosis
... embryos lacking PS receptors conducted by Ming O. Li and colleagues [7] , un-ingested cells undergoing apoptosis accumulated in the brain and lungs,
leading to neonatal lethality. These studies show how critical is the role of PS receptor (PSR) in the development of complex organisms such as mammals.
...
ATP synthase
... subunit of F 1 , while the major F 1 subunits are fixed in place. This rotation forces a conformational change in the F 1 particle, eventually
leading to the synthesis of ATP. For elucidating this Boyer and Walker shared in the 1997 Nobel Prize in Chemistry .
Physiological role
The F 1 F O ...
Avian influenza
... radius of the location of this outbreak.
An outbreak of avian influenza in January 2005 affected 33 out of 64 cities and provinces in Vietnam,
leading to the forced killing of nearly 1.2 million poultry. Up to 140 million birds are believed to have died or were killed because of the outbreak. As of ...
Barbiturate
... therapeutically without harm, concern about the addiction potential (withdrawal symptoms can include tonic-clonic or grand mal seizures potentially
leading to permanent disability or even death) of barbiturates and the
ever-increasing number of fatalities associated with them led to the development of ...
Charles Darwin
... Owen , leader of the scientific establishment Huxley was trying to overthrow. Owen initially appeared neutral, but his review condemned the book,
leading Darwin to feel that an envious Owen hated him. The Church of England scientific establishment reacted against the book, and Darwin's old Cambridge ...
Chromatography
... which decreases the time the separated components remain on the stationary phase and thus the time they have to spread out within the column,
leading to broader peaks. Less time on the column then translates to narrower peaks in the resulting chromatogram and thence to better selectivity (it's ...
Cisterna
... end of the Golgi where transport to other parts of the cell occurs is called the trans-Golgi network. Both are thought to be specialized cisternae
leading in and out of the Golgi apparatus.
...
Colchicine
... . Apart from inhibiting mitosis , a process heavily dependent on cytoskeletal changes, it also inhibits neutrophil motility and activity,
leading to a net anti-inflammatory effect.
Colchicine as medicine
Colchicine is FDA -approved for the treatment of gout and also for familial ...
Culture
... are mundane in the United States, but were considered exotic when introduced in China. "Stimulus diffusion" refers to an element of one culture
leading to an invention in another. Diffusions of innovations theory presents a research-based model for why and when individuals and cultures adopt new ...
Disulfide bond
... for example, virtually intact hair has been recovered from ancient Egyptian tombs. Different parts of the hair have different cysteine levels,
leading to harder or softer material. Breaking and making disulfide bonds governs the phenomenon of wavy or frizzy hair.
External links
Disulfide ...
Eugenics
... , Darwin noted that while Galton's formulation of the peril of civilization might be correct, the very human sensitivities that Galton thought were
leading to inevitable doom were themselves also evolved and were part of a fundamental core of what distinguished man as a highly-evolved social species. On ...
Evolution
... , of modern animals. About 500 million years ago, plants and fungi colonized the land, and were soon followed by arthropods and other animals,
leading to the development of land ecosystems with which we are familiar.
The emergence of novel traits
Mechanisms of inheritance
In Darwin's ...
Gene
... showed that mutations in genes caused errors in certain steps in metabolic pathways . This showed that specific genes code for specific proteins,
leading to the "one gene, one enzyme" hypothesis. Oswald Avery , Collin Macleod , and Maclyn McCarty showed in 1944 that DNA holds the gene's ...
Genetic recombination
... separated. In this process alleles are replaced by different alleles from the same genes thereby preserving the structure of genes. One mechanism
leading to recombination is chromosomal crossing over . In analog fashion exchange of alleles is possible between homologous sites within one DNA ...
Hepatitis B
... D increases the risk of liver cirrhosis and subsequently, liver cancer.
Hepatitis B infection may lead to a chronic inflammation of the liver,
leading to cirrhosis . This type of infection dramatically increases the incidence of liver cancer .
The greater a person's age at the time of infection, ...
Human
... type is called nationalism or patriotism . In extreme cases, feelings of loyalty towards an institution or authority can become pathological ,
leading to mass hysteria or fascism . (See also Milgram experiment , Stanford prison experiment .)
Consciousness
Main articles: Consciousness , ...
Human Genome Project
... stages. In the future the knowledge gained by the understanding of the genome will boost the fields of medicine and biotechnology , eventually
leading to cures for cancer , Alzheimers disease and other diseases.
On a more philosophical level, the analysis of similarities between DNA sequences ...
Intron
... the introns-early model ancestral genes are believed to have included a large number of introns, some of which have been lost over evolutionary time,
leading to the different but similar intron patterns in related genes of different species. The introns-late model suggests instead that introns occur in the ...
Light-dependent reaction
... which uses them to drive the reaction
NADP + + H + + 2e - → NADPH
This consumes the H + ions produced by the splitting of water,
leading to a net production of O 2 , ATP, and NADPH with the consumption of solar photons and water.
...
Metabolism
... and compounds from simple precursors:
Glycogenesis
Gluconeogenesis
Porphyrin synthesis pathway
HMG-CoA reductase pathway ,
leading to cholesterol and isoprenoids .
Secondary metabolism , metabolic pathways that are not essential for growth, development or reproduction, but ...
Actin
... destabilizes the filament. ADP-actin dissociates from the minus end and the increase in ADP-actin stimulates the exchange of bound ADP for ATP,
leading to more ATP-actin units. This rapid turnover is important for the cells movement.
The protein cofilin binds to ADP-actin units and promotes their ...
Molecular biology
... molecular biology as:
... not so much a technique as an approach, an approach from the viewpoint of the so-called basic sciences with the
leading idea of searching below the large-scale manifestations of classical biology for the corresponding molecular plan. It is concerned particularly with ...
Neurotransmitter
... calcium ion channels to open. Calcium then stimulates the transport of vesicles to the synaptic membrane: the vesicle and cell membrane fuse,
leading to the release of the packaged neurotransmitter, a mechanism called exocytosis .
The neurotransmitters then diffuse across the synaptic cleft to ...
Origin of life
... later in that decade.
Hybrid models
A growing realization of the inadequacy of either pure "genes-first" or "metabolism-first" models is
leading the trend towards models that incorporate aspects of each.
Other models
Clay theory of the origin of life
A hypothesis for the origin of ...
Polymerase chain reaction
... Taq. Taq polymerase is widely used in current PCR practice (May 2004). A disadvantage of Taq is that it sometimes makes mistakes when copying DNA,
leading to mutations (errors) in the DNA sequence, since it lacks 3'->5' proofreading exonuclease activity. Polymerases such as Pwo or Pfu, obtained ...
Light-dependent reaction
... which uses them to drive the reaction
NADP + + H + + 2e - → NADPH
This consumes the H + ions produced by the splitting of water,
leading to a net production of O 2 , ATP, and NADPH with the consumption of solar photons and water.
...
Alga
... - cells forming a thallus with partial differentiation of tissues
In three lines even higher levels of organization have been reached,
leading to organisms with full tissue differentiation. These are the brown algae —some of which may reach 70 m in length ( kelps )—the red ...
Prokaryote
... arose, they diversifed explosively throughout their long existence. The metabolism of prokaryotes is far more varied than that of eukaryotes,
leading to many highly distinct types of prokaryotes. For example, in addition to using photosynthesis or an organic form of carbon for energy like ...
Protein biosynthesis
... functional groups , such as acetate , phosphate , various lipids and carbohydrates . Enzymes may also remove one or more amino acids from the
leading (amino) end of the polypeptide chain, leaving a protein consisting of two polypeptide chains connected by disulfide bonds.
External links
...