inhibitor

Selective serotonin reuptake inhibitor

... Ozpoyraz, N. (2002). Selective serotonin reuptake inhibitor discontinuation syndrome: a review. Advances in Therapy 19(1): 17-26. .....

Proton pump

...oplast electron transfer chain proton pump inhibitor ATP synthase...

Neurotransmitter

...r. For example, GABA can act as a rapid or slow inhibitor , depending on whether an ionotropic or metabotropic receptor is the target of the molecule. Small molecule transmitters tend to have consistently inhibitory or excitatory action on their targets. Meanwhile, the same polypeptide may have inhibitory o...

Competitive inhibitor

...e molecules cannot enter the active site while the inhibitor is there, and inhibitors cannot enter the site whe...d vice-versa. In noncompetitive inhibition , the inhibitor works by occupying some other site on the enzyme. Because of this, the substrate and inhibitor do no...

Cancer

...d neck cancer . Finasteride , a 5-alpha reductase inhibitor , has been shown to lower the risk of prostate cancer. Other examples of drugs that show promise for chemoprevention include COX-2 inhibitors (which inhibit a cyclooxygenase enzyme involved in the synthesis of proinflammatory prostaglandins ). ...

Apoptosis

...l lung cancer cells). They found that the X-linked inhibitor of apoptosis protein (XIAP) is overexpressed in H460 cells. XIAPs bind to the processed form of caspase-9, and suppress the activity of apoptotic activator cytochrome c (see previous section on biochemical execution). The apoptotic pathway was foun...

Active site

...by the enzyme. In noncompetitive inhibition , the inhibitor binds to the enzyme at another site, the alloster...milar to noncompetitive inhibition except that the inhibitor can only bind the enzyme-substrate complex rather than the free enzyme. Models There are several...