glycoprotein

Zona pellucida

The zona pellucida is a glycoprotein matrix surrounding the plasma membrane of a mammalian oocyte . This structure binds spermatozoa , and is required to initiate the acrosome reaction . The zona glycoprotein, ZP3 , is responsible for sperm binding, adhering to proteins on...

Blood type

...d cells, the ABO antigen is also expressed on the glycoprotein von Willebrand factor (vWF), which participates in hemostasis (control of bleeding). In fact, blood type O predisposes very slightly to bleeding, as vWF is degraded more rapidly. Austrian scientist Karl Landsteiner was awarded the Nobel Priz...

Monoclonal antibody

...s purpose, since they cannot produce this kind of glycoprotein ). Depending on how big a part of the mouse antibody is used, one talks about chimeric antibodies or humanized antibodies . Another approach involves genetically engineered mice that produce more human-like antibodies. FDA approved monoclonal ...

Immune system

...ry nucleated cell contains molecules of a large glycoprotein called the major histocompatibility complex (MHC). These proteins have configurations and amino acid sequences that are unique to every individual. T cells, a group that encompasses cytotoxic T lymphocytes ( CTLs ), the cells that kill virally-in...

Glycoprotein

A glycoprotein is a macromolecule composed of a protein and a carbohydrate (a sugar ). The carbohydrate is usually attached to the protein in a posttranslational modification , at either asparagine , hydroxylysine , hydroxyproline , serine , or threon...

Ebola

...diameter of 40-50 nm and an interval of 5 nm. 7 nm glycoprotein spikes that are 10 nm apart from each other are present within the outer envelope of the virus, which is derived from the host cell membrane. Each viral particle contains one molecule of single-stranded, negative-sense RNA , which encodes the seven ...