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Fusion in Biological Definition

Cell growth

... means to produce very large cells is by cell fusion to form syncytia . For example, very long (several inches) skeletal muscle cells are formed by fusion of thousands of myocytes . Genetic studies of ... the formation of multinucleated muscle cells by fusion of myocyes. Some of the key proteins are ...

Affinity chromatography

... for affinity binding (if the molecule is a protein these are called fusion proteins ). Such tags include six His tags (six Histidine residues added ... antibodies to bind (that is any antibodies against the GST part of the fusion protein will be removed). The serum is then separated from the solid ...

Archaea

... in certain bacteria , such as Thermotoga , makes their relationship difficult to determine. Some have suggested that eukaryotes arose through fusion of an archaean and eubacterium, which became the nucleus and cytoplasm, which accounts for various genetic similarities but runs into difficulties ...

Bone

... Epiphysis the end regions of the bone; regions of secondary ossification Epiphyseal plate the thin sheet of bone marking the fusion of epiphyses to the diaphysis (adults only) Head the proximal articular end of the bone Neck the region of bone between the Head ...

Chromatography

... not very robust . It is often used in biochemistry in the purification of proteins (or better: protein constructs). These constructs can be of fusion proteins with a so-called his-tag , biotinylated or possibly antigens . After purification some of these tags are usually removed and the pure ...

Eukaryote

... haploid generations, where only one copy of each chromosome is present, and diploid generations, where two are present, occurring through nuclear fusion (syngamy) and meiosis . There is considerable variation in this pattern, however. Origin and evolution The origin of the eukaryotic cell ...

Gamete

... of chromosomes and therefore diploid . The zygote cell receives one set of chromosomes from each of the two gametes involved in the union. After fusion of the two gamete nuclei , and after multiple cell divisions and cellular differentiation , a zygote develops , first into an embryo , and ...

Fungus

... result is that nuclei move from one mycelium into the other, forming a heterokaryon (meaning different nuclei). This is called plasmogamy . Actual fusion to form diploid nuclei is called karyogamy , and may not occur until sporangia are formed. In the Zygomycota , the heterokaryon produces ...

His-tag

... can be used in affinity chromatography together with a column that has nickel bound to it. Histidine is a good ligand for nickel so the fusion protein will bind to the column. The protein can be eluted with a solution of imidazole . Detection The his tag can also be used in ...

Human

... introduced a greater emphasis on the individual, as well as the ideas of salvation , divine grace , and divine incarnation . Subsequently, the fusion of Hellenic and Christian thought led to the development of theology . Islam , established six centuries after Christianity, rejects the ...

Joint

... joined by one of more ligaments. Synchondroses are joints where the two bones are joined by a piece of cartilage. Synostoses are the fusion of two bones, to the point that they are practically one bone. In humans, the plates of the cranium, initially separate, fuse together as the child ...

Lynn Margulis

... mainly from random mutations. Rather new tissues, organs, and even new species evolve primarily through the long-lasting intimacy of strangers. The fusion of genomes in symbioses followed by natural selection, she suggests, leads to increasingly complex levels of individuality." [1] " After the ...

Meiosis

... eventually produces a total of four daughter cells, each with an haploid set of chromosomes. Significance of meiosis If meiosis did not occur, fusion of the gametes would not result in a diploid condition (2n) but 4n. Meiosis also provides opportunities for new combination (through crossing over ...

Monoclonal antibody

... with the antigen. These B-cells are then fused with myeloma tumor cells that can grow indefinitely in culture (myeloma is a B-cell cancer). This fusion is done by making the cell membranes more permeable. The fused hybrid cells (called hybridomas ) will multiply rapidly and indefinitely (since ...

Polymerase chain reaction

... example, medicines or enzymes in biological washing powders. The incorporation of an affinity tag on a recombinant protein will generate a fusion protein which can be more easily purified by affinity chromatography . Figure 5 : Cloning a gene using a plasmid. (1) Chromosomal DNA of ...

Species

... species may occasionally provide the energy to impel rapid evolutionary ... 2004-01-09 ScienceDaily: Mayo Researchers Observe Genetic fusion Of Human, Animal Cells; May Help Explain Origin Of AIDS Quote: ... researchers have discovered conditions in which pig cells and human cells ...

Synapse

... -based computations in computers , and so are thought to figure similarly in neural circuits. Detailed properties and regulation Following fusion of the synaptic vesicles and release of transmitter molecules into the synaptic cleft, the neurotransmitter is rapidly cleared from the space for ...
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