coding

RNA

...mplate strand ; the opposite strand is called the coding strand (so called because it logically has the equivalent nucleotide sequence of the new RNA strand). A small stretch of DNA-RNA hybrid is present at the active site of the enzyme. The synthesis continues until a termination sequence is reached. Th...

Protein biosynthesis

...and of the DNA double helix. This is called the coding strand . The transcription starts with initiation....travels through the strand that is opposite to the coding strand (the cell wants a copy of the coding strand, so it needs to copy that from the DNA that is th...

Molecular biology

...tion is expression cloning. In this technique, DNA coding for a protein of interest is cloned (using PCR ...ls are said to be transduced. In either case, DNA coding for a protein of interest is now inside a cell, and the protein can now be expressed. A variety of s...

Isozyme

...on-deletion ( indel ) events that affect the DNA coding sequence of the gene . As with any other new mutation , there are three things that may happen to a new allozyme: (1) It is most likely that the new allele will be non-functional - in which case it will probably result in low fitness and be...

Genomics

...e has functional significance. It may be a protein coding sequence or regulatory region. Experimental invest... 85% comparing all protein coding sequences, NHGRI Dog 95% Jon Entine in the San Francisco Examiner ...

Genetic code

...osed of tri-nucleotide units called codons , each coding for a single amino acid. Each nucleotide sub-unit ...s an initiation site: the first AUG in an mRNA 's coding region is where translation into protein begins. 2 This is a start codon for prokaryotes only. ...

Gene

...nce of the amino acids that make up a protein. The coding of a three nucleotide DNA sequence to a specific...diate way to know whether this pattern arises from coding sequences or regulatory sequences. Typically, he or she will simply attribute it to variations withi...

Expressed sequence tag

...e of a transcribed protein -coding or non-protein coding DNA sequence . It was originally intended as a way to identify gene transcripts , but has since been instrumental in gene discovery and sequence determination. An EST is produced by one-shot sequencing of a cloned mRNA , and the resulting seque...

DNA

...op' or 'nonsense' codons signifying the end of the coding region. In many species of organism, only a small fraction of the total sequence of the genome appears to encode protein. The function of the rest is a matter of speculation. It is known that certain nucleotide sequences specify affinity for DN...

DNA sequence

... sense or anti-sense (see DNA ), and either coding or noncoding . DNA sequences can also contain " junk DNA ". See also DNA DNA motif...

Genetic code

...osed of tri-nucleotide units called codons , each coding for a single amino acid. Each nucleotide sub-unit ...s an initiation site: the first AUG in an mRNA 's coding region is where translation into protein begins. 2 This is a start codon for prokaryotes only. ...

Antibiotic

.... The situation is worsened by the fact that genes coding for antibiotic resistance can be transferred between bacteria, making it possible for bacteria never exposed to an antibiotic to acquire resistance from those which have. The problem of antibiotic resistance is worsened when antibiotics are used to t...

Alternative splicing

...a twofold information structure: A DNA sequence coding for the pre-mRNA An additional DNA code or other...ics it means that the old idea of one DNA sequence coding for one polypeptide (the "one-gene-one-protein" hypothesis) is no longer correct. External informa...