block

Unsolved problems in biology

...ete function of the regulator genes ? The building block of life may be a precursor to a generation of electronic devices and computers , but what are the electronic properties of DNA? Does Junk DNA function as molecular garbage? Consciousness / Self . What is it? Why is it necessary for many ...

Reverse genetics

... target messenger RNA (mRNA), Morpholinos bind and block access to the target mRNA without requiring the activity of cellular proteins and without necessarily accelerating mRNA degradation. Morpholinos are effective is systems ranging in complexity from cell-free translation in a test tube to humans. Fin...

Long-term potentiation

...estbrook GL, Guthrie PB (1984) "Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones". Nature 309 (5965), 261-3. PMID 6325946 ^ Rogan MT, Staubli UV, LeDoux JE (1997) "Fear conditioning induces associative long-term potentiation in the amygdala". Nature 390 (6660),...

Lac repressor

...ne of these two forms it can lock onto the DNA and block RNA polymerase. Electrostatic forces hold it in place. When lactose is present the lac repressor hooks up to lactose and changes shape and detaches from the DNA. The technical term for this shape-shifting is " allosteric signal transduction "....

Competitive inhibitor

...e distinguishes two ways in which a molecule may block the action of an enzymes : competitive and noncompetitive inhibition. In competitive inhibition , the molecule acts on the same active site as the normal enzyme substrate . The substrate molecules cannot enter the active site while the inhibitor ...

Antibody

...for phagocytosis by macrophages and other cells, block viral receptors and stimulate other immune respo...t pathway . Antibodies that recognize viruses can block these directly by their sheer size. The virus will be unable to dock to a cell and infect it, hinder...