autoimmune

T cell

...es but normally is controlled so it does not cause autoimmune diseases). This process is called negative selection . T cells go into apoptosis if they cannot express their TCR receptors, if they aren't positively selected or if they get removed by negative selection. About 98% of T cells die in the thymus. Th...

Muscle

...dermatomyositis and inclusion-body myositis are autoimmune conditions in which the muscle is affected. Rhabdomyolysis is the breakdown of muscular tissue due to any cause. While it may not lead to any muscular symptoms at all, the myoglobin thus released may cause acute renal failure . Tumors of m...

Major histocompatibility complex

...or running amok and causing harm to the body (see autoimmune disorders .) All Mhc molecules receive polypeptides from inside the cells they are part of and display them on the cell's exterior surface for recognition by T cells . However, there are major differences between MHC class I and II in the method...

Liver

...is , an inflammatory disease of the bile duct , autoimmune in nature. Primary biliary cirrhosis , autoimmune disease of small bile ducts Budd-Chiari syndrome , obstruction of the hepatic vein. A number of...

Immunology

... of the immune system in immunological disorders ( autoimmune diseases , hypersensitivities , immune deficienc...people suffering from other immune deficiencies or autoimmune diseases. Diagnostic immunology The specificity of the bond between antibody and antigen has mad...

Immune system

...ures in a number of other disorders, particularly autoimmune disorders such as lupus erythematosus , type I ...c determinant / epitope / hapten / memory cell autoimmune disorders CD4 receptor /CD8 receptor / perforin / apoptosis /clonal selection immunosuppressi...

Hormone

...oxine , for hypothyroidism ) and steroids (for autoimmune diseases and several respiratory disorders ). Insulin is used by many diabetics . Local preparations for use in otolaryngology often contain pharmacologic equivalents of adrenalin , while steroid and vitamin D creams are used extensively ...

Diabetes mellitus

...scents, but can occur in adults as well. It is an autoimmune disorder , in which the body's own immune system ...hem sufficiently to reduce insulin production. The autoimmune attack may be triggered by reaction to an infection, for example by one of the viruses of the Coxsa...

Apoptosis

...vivors are tested as well for potentially damaging autoimmune reactions, and those that show high affinity to he...veral human diseases, especially (but not only) in autoimmune diseases, such as diabetes and multiple sclerosis. Implication and role of apoptosis in diverse ...