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Site in Biological Definition

Active site

... The active site of an enzyme is the binding site where catalysis occurs. The structure and chemical properties of the active site allow the recognition and binding of the ...

Allostery

... effector molecule at a so-called allosteric site . Changes that enhance activity are referred to ... collides with a molecule of substrate, the active site essentially forms a glove around its substrate. ... and the effector. The allosteric, or "other," site is the ...

Allostery

... effector molecule at a so-called allosteric site . Changes that enhance activity are referred to ... collides with a molecule of substrate, the active site essentially forms a glove around its substrate. ... and the effector. The allosteric, or "other," site is the ...

Centromere

... the kinetochore is assembled. Thus, it is the site where spindle fibers of the mitotic spindle ... the chromosome during mitosis . It is also the site of the primary constriction visible in microscopy ... indicating that there is not a primary site of microtubule attachments or a primary ...

Competitive inhibitor

... inhibition , the molecule acts on the same active site as the normal enzyme substrate . The substrate molecules cannot enter the active site while the inhibitor is there, and inhibitors cannot enter the site when the substrate is there. Characteristic for ...

Down syndrome

... (Online book) Down Syndrome Information web site National Down Syndrome Society web site National Down Syndrome Congress web site The Down Syndrome Educational Trust ...

Enzyme

... where the substrate (s) attach, and active site (s), where the amino acids perform the catalysis; ... functionally related amino acids of the active site widely dispersed throughout the amino acid chain, ... associated genes. Cytochrome P450 enzymes site lists over 4000 versions of enzymes from this ...

Malaria

... PMID 12024215 External links WHO site on malaria CDC site on malaria Medline Plus site on malaria Malaria Vaccine Initiative ...

Kidney

... the cortical collecting duct the medullary collecting duct . The site where the ascending loop of Henle touches the afferent arteriole, is ... macula densa and juxtaglomerular cells . Juxtaglomerular cells are the site of renin synthesis and secretion. Fluids become more concentrated ...

Lambda phage

... The integration of phage λ takes place at a special attachment site in the bacterial genome, called att λ . The sequence of the att site is called att B and consists of the parts B-O-B', whereas ...

Operon

... of DNA : an operator (the switch) a promoter (a binding site for the transcription enzyme ). The switch of an operon (that is, the ... called a repressor. In summary: The "operator" is a DNA binding site for a repressor; transcription of the structural genes takes place ...

Promoter

... Promoter elements Core promoter Transcription Start site (TSS) Approximately -35 A binding site for RNA polymerase RNA-polymerase I: transcribes genes encoding ...

Protein

... . The strength of ligand-protein binding is a property of the binding site known as affinity . Since proteins are involved in practically every ... Allosteric modulation : When the binding of a ligand at one site on a protein affects the binding of ligand at another site. Covalent ...

Active transport

... or concentration gradient (collectively termed an electrochemical gradient ). This is achieved by either altering the affinity of the binding site or altering the rate at which the protein changes conformations. Contents showTocToggle("show","hide") 1 Types 1.1 Primary ...

Antibody

... Fab fragment. It is composed of one constant and one variable domain of each the heavy and the light chain, which together shape the antigen binding site at the amino terminal end of the monomer. The two variable domains bind the antigens they are specific for and that elicited their production. ...

Biology

... source for everything biology related. Kimball's Biology Pages : An online searchable textbook. Biology Online : One person-maintained site with tutorials. The Tree of Life : A multi-authored, distributed Internet project containing information about phylogeny and biodiversity. ...

Cancer

... can also be used to treat leukemia and lymphoma (cancers of the blood-forming cells and lymphatic system, respectively). Radiation dose to each site depends on a number of factors, including the type of cancer and whether there are tissues and organs nearby that may be damaged by radiation. ...

Cooperativity

... is a phenomenon in biology displayed by enzymes or receptors that have multiple binding sites . When substrate bonds to the active site of one enzymatic subunit, the rest of the subunits are stimulated and become active. ...

Dialysis

... is the very high potential for infection with an open catheter; peritonitis is a common complication, as are infections of the catheter exit site or "tunnel" (path from the peritoneum to the exit site). Because of this, patients are advised to take a number of precautions against infection. ...

Endoplasmic reticulum

... an ER. ER's base structure and composition is similar to the plasma membrane , though it is an extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and ...

Enhancer

... and the other with its promoter . An abstract can be found here .) An enhancer does not need to bind close to the transcription initiation site to affect its transcription, as some have been found to bind several hundreds of thousands base pairs upstream or downstream of the start site. ...

Evolution

... for estimating when various lineages developed. As fossilization is an uncommon occurrence, usually requiring hard parts (like bone) and death near a site where sediments are being deposited, the fossil record only provides sparse and intermittent information about the evolution of life. Fossil ...

Facilitated diffusion

... helped across by transport proteins. The transport protein involved is intrinsic, that is, it completely spans the membrane. It also has a binding site for the specific molecule (e.g., glucose ) or ion to be transported. After binding the molecule, the protein changes shape and carries the molecule ...

Foot and mouth disease

... single-stranded RNA (ribonucleid acid, the viral genetic material). When such a virus comes in contact with a host cell, it binds to a receptor site and triggers a folding-in of the cell membrane. Once the virus is inside the host cell, its protein coat dissolves. New viral RNA and components of ...

Gene therapy

... harder than modifying simple bacteria, primarily because of the problems involved in carrying large sections of DNA and delivering it to the right site on the genome. Types of gene therapy In theory it is possible to transform either somatic cells (most cells of the body) or cells of the ...

Glycolipid

... eukaryotic cell membranes. They extend from the phospholipid bilayer into the aqueous environment outside the cell where it acts as a recognition site for specific chemicals as well as helping to maintain the stability of the membrane and attaching cells to one another to form tissues . ...

Isozyme

... if the amino acid residue that is changed is in a relatively unimportant part of the enzyme, for example a long way from the active site then the mutation may be selectively neutral and subject to genetic drift . (3) In rare cases the mutation may result in an enzyme that is more ...

Lipase

... D. L. Ollis. 1999. Of barn owls and bankers: a lush variety of alpha/beta hydrolases. Structure Fold Des 7:R141-6. Lowe, M. E. 1992. The catalytic site residues and interfacial binding of human pancreatic lipase. J Biol Chem 267:17069-73. Schrag, J. D., and M. Cygler. 1997. Lipases and alpha/beta ...

Liver

... substances, including glucose in the form of glycogen, vitamin B12 , iron , and copper . In the first trimester fetus , the liver is the main site of red blood cell production. By the 42nd week of gestation, the bone marrow has almost completely taken over that task. Producing an ...

Nutrition

... of the SCN is to raise awareness of nutrition problems and mobilize commitment to solve them -- at global, regional and national levels". The site is available in English, French and Portuguese Disclaimer Please remember that Wikipedia is offered for informational use only. The ...

Passive transport

... to fit through the membrane pores. Therefore, it will bind with its specific carrier proteins, and the complex will then be bonded to a receptor site and moved through the cellular membrane. Bear in mind, however, that facilitated diffusion is a passive process, and the solutes still move down the ...

Proprioception

... factors such as chemotherapy . External links The Imperial Society of Teachers of Dancing A comprehensive Alexander Technique site ...

RNA

... because it logically has the equivalent nucleotide sequence of the new RNA strand). A small stretch of DNA-RNA hybrid is present at the active site of the enzyme. The synthesis continues until a termination sequence is reached. The resulting RNA molecule is the primary transcript . Modulation of ...

Endoplasmic reticulum

... an ER. ER's base structure and composition is similar to the plasma membrane , though it is an extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and ...

Rudolf Steiner

... survived the blaze (the Glasshaus, Haus Duldeck, the Transformerhaus, etc.). Construction of the second Goetheanum building began on the same site shortly before he died in 1925. He conceived it as an organic extension and metamorphosis of the first building, inspiring and pre-dating architects ...

Endoplasmic reticulum

... an ER. ER's base structure and composition is similar to the plasma membrane , though it is an extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and ...

Endoplasmic reticulum

... an ER. ER's base structure and composition is similar to the plasma membrane , though it is an extension of the nuclear membrane . The ER is the site of the translation and folding of and transport of proteins that are to become part of the cell membrane (e.g., transmembrane receptors and ...

Transport protein

... A transport protein is a protein involved in facilitated diffusion . Changes in the conformation move the binding site to the opposite side of the protein. There are 3 types of transport proteins, uniporter , symporter / coporter , and antiporter , which ...
Other Contents
(Date:8/31/2014)... and accurate tool to diagnose tuberculosis in children, ... test (TAM-TB assay) is the first reliable immunodiagnostic ... test features excellent specificity, a similar sensitivity as ... blood test. The promising findings are a major ... particularly in tuberculosis-endemic regions. , The study has ...
(Date:8/31/2014)... the greatest challenges in modern medicine is developing drugs ... minimal toxicity and side-effects to the patient. Such properties ... drug molecule. Ideally, the drug should have a shape ... that it binds it with high specificity. Publishing in ... synthetic amino acid that can impact the 3D structure ...
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