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Microscope in Biological Definition

Anton van Leeuwenhoek

... known for his contribution to improvement of the microscope and his contributions towards the establishment of cell biology . Using his handcrafted microscope he was the first to observe and describe muscle ... over 500 optical lenses during his lifetime. His microscope was used and improved by Christiaan Huygens for ...

Microscope

... 1852 microscope A microscope ( Greek : micron = small and scopos = aim) ... the unaided eye. In other words, requiring a microscope to examine. The most common type of ...

Chromosome

... context in which individual chromosomes are visible with an optical microscope . Prokaryotes do not possess histones or nuclei. In its relaxed state, ... females, one of the two X chromosomes is inactive and can be seen under a microscope as Barr bodies . Human chromosome Chromosome Genes ...

Marcello Malpighi

... his name to several physiological features. He was pioneer in using a microscope and he has also been described as a founder of comparative physiology ... such recognition given to an Italian. Research Malpighi used the microscope for studies on skin , kidney , and for the first interspecies ...

Abiogenesis

... spontaneous generation did not occur, but that omne vivum ex ovo , every living thing came from a pre-existing living thing. The discovery of the microscope carried the refutation further. In 1683 Antoni van Leeuwenhoek discovered bacteria, and it was soon found that however carefully organic matter ...

Apoptosis

... regulators Apoptotic process Morphology A cell undergoing apoptosis shows a characteristic morphology that can be seen under a microscope : The cell becomes round (circular). This occurs because the protein structures that conform the cytoskeleton are digested by specialized ...

ATP synthase

... membrane. The F 1 particle was first isolated by Ephraim Racker in 1961. The F 1 particle is large and can be seen in the transmission electron microscope by negative staining (1962, Fernandez-Moran et al., Journal of Molecular Biology, Vol 22, p 63). These are particles of 9 nm diameter that pepper the ...

Bacterium

... 11 External links History and taxonomy The first bacteria were observed by Antony van Leeuwenhoek in 1683 using a single-lens microscope of his own design. The name bacterium was introduced much later, by Ehrenberg in 1828 , derived from the Greek word ...

Biological tissue

... or, in connection with disease, histopathology . The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope , though developments in electron microscopy , immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of ...

Cancer

... cell adhesion . Some cell adhesion proteins are tumor suppressor genes . Morphology Cancer tissue has a distinctive appearance under the microscope . Among the distinguishing traits are a large number of dividing cells, variation in nuclear size and shape, variation in cell size and shape, loss ...

DNA

... Deoxyribose Nucleic Acid ". April 2, 1953. (paper on the structure of DNA) DNA Interactive (requires Macromedia Flash ) DNA under electron microscope ...

Electrophysiology

... to establish an electrochemical junction with the pipet fluid and the tissue or cell into which the pipet is inserted (typically with the aid of a microscope and finely adjustable pipet holders, known as micromanipulators). The chloride-coated silver wire connects back to the amplifier. Classically, ...

Bacterium

... 11 External links History and taxonomy The first bacteria were observed by Antony van Leeuwenhoek in 1683 using a single-lens microscope of his own design. The name bacterium was introduced much later, by Ehrenberg in 1828 , derived from the Greek word ...

Cell membrane

... primarily mechanical support. The plasma membrane is only about 10 nm thick and may be discerned only faintly with a transmission electron microscope . One of the key roles of the membrane is to maintain the cell potential . Contents showTocToggle("show","hide") 1 A Fluid Mosaic ...

Infertility

... analysis of the ejaculate , which contains the sperm . The analysis includes counting the number of sperm and measuring their motility under a microscope : Producing few sperm, oligospermia , or no sperm, azoospermia . A sample of sperm that is normal in number but shows poor motility, or ...

Immunology

... enzyme and are used as a "probe" to detect it. Well known applications of this include immunoblotting , ELISA and immunohistochemical staining of microscope slides. The speed, accuracy and simplicity of such tests has led to the development of rapid techniques for the diagnosis of disease, microbes and ...

Insulin

... Discovery and characterization In 1869 Paul Langerhans , a medical student in Berlin , was studying the structure of the pancreas under a new microscope when he noticed some previously unidentified cells scattered in the exocrine tissue. The function of the "little heaps of cells", later known as ...

Nucleosome

... in eukaryotes . All chromatin (except for that packaged in the sperm nucleus) consists of nucleosomes. Nucleosomes can be seen with an electron microscope as bead-like structures along the DNA. Structure The histones make up the central core particle of the nucleosome. The DNA is ...

Cell membrane

... primarily mechanical support. The plasma membrane is only about 10 nm thick and may be discerned only faintly with a transmission electron microscope . One of the key roles of the membrane is to maintain the cell potential . Contents showTocToggle("show","hide") 1 A Fluid Mosaic ...

Proteomics

... of human genes from previous estimates. Proteomic World - Resources for proteomics research. Yeast GFP Localization Database - Database of microscope images and quantitation for most of the yeast proteome. References Twyman, R. M. 2004. Principles of proteomics. BIOS Scientific ...

Starch

... added to a sample containing starch (specifically amylose) will turn an intense blue-black colour, otherwise it will stay yellow-orange. Under the microscope , starch grains show a distinctive Maltese Cross effect (also known as 'extinction cross') under polarised light . External links Jones, ...

Stoma

... with transparent nail varnish.(or thin layer of PVA glue ) Allow to dry out thoroughly (takes a good 30 minutes). Peel off and place on a microscope slide. The stomata leave clearly visible impressions in the nail varnish. A graticule slide allows for the counting of how many stomata (per ...

Tobacco mosaic virus

... tobacco, tomato, pepper, cucumbers, and a number of ornamental flowers. There are many different strains. External links Electron microscope image of TMV Several EM images and schematic drawings Images of the TMV coat protein ...

Tobacco mosaic virus

... tobacco, tomato, pepper, cucumbers, and a number of ornamental flowers. There are many different strains. External links Electron microscope image of TMV Several EM images and schematic drawings Images of the TMV coat protein ...
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