Homozygote

... . When an organism is referred to as being homozygous for a specific gene, it means that it carries ... (e.g. the genotype is AA or aa ). A homozygous dominant genotype occurs when a particular locus ... alleles for the dominant trait (e.g. AA ). A homozygous recessive genotype occurs when a particular ...

Molecular evolution

... to determine for a finite population what proportion of loci would be homozygous . This was, in part, motivated by assertions by other geneticists that ... genotypes would be cancelled out by continual generation of less fit homozygous genotypes. These results became important in the formation of the ...

Polymerase chain reaction

... on an agarose gel, and the band pattern will tell you if the individual is homozygous T, homozygous C, or heterzygous T/C. This methodology has several applications, such as ...

Allele

... and thus contain two copies of each gene. An organism in which both copies of the gene are identical - that is, have the same allele - is said to be homozygous for that gene. An organism which has two different alleles of the gene is said to be heterozygous . Often one allele is "dominant" and the other is ...

Allele frequency

... population will be heterozygous for the allele (i.e. carry one copy of that allele and one copy of another in each somatic cell) and 4% will be homozygous (carrying two copies of the allele). So all together 36% of diploid individuals would be expected to carry an allele that has a frequency of 20%. ...

Evolution

... through a number of mechanisms, including: Overdominance or heterozygote advantage , where the heterozygote is more fit than either of the homozygous forms (famously exemplified by human sickle cell anemia conferring resistance to malaria ) Frequency-dependent selection , where the rare ...

Locus

... sequence) on a chromosome . A locus can be occupied by any of the alleles of the gene. Diploid or polyploid cells are either homozygous (have the same allele at a locus) or heterozygous (have different alleles at a locus). In mathematics , a locus is the set of points ...