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Downstream in Biological Definition

Apoptosis

... loop that spirals into increasing release of pro-apoptotic factors from mitochondria (see below), and the amplified activation of caspase-8. downstream from TNF-R1 and Fas activation - at least in mammalian cells - a balance between pro- (like BAX, BID, or BAD) and anti-apoptotic (Bcl-Xl and Bcl-2) ...

Barr body

... evidence suggests that the maternally inherited gene may be imprinted . It is thought that this constitutes the mechanism of choice, and allows downstream processes to establish the compact state of the Barr body. These changes include histone modifications, such as histone H3 methylation and ...

Blood

... ( amino acids , lipids , hormones ) to be transported between tissues and organs. Problems with blood composition or circulation can lead to downstream tissue dysfunction. Contents showTocToggle("show","hide") 1 Blood of different species 1.1 Humans 1.2 Small invertebrates ...

Enhancer

... transcription initiation site to affect its transcription, as some have been found to bind several hundreds of thousands base pairs upstream or downstream of the start site. Enhancers can also be found inside introns . An enhancer's orientation may even be reversed without affecting its function. ...

Promoter

... nucleotides TTGACA. Its presence allows a very high transcription rate. <-- upstream downstream 5'-XXXXXXXPPPPPXXXXXXPPPPPPXXXXGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGXXXX-3' -35 -10 Gene to be transcribed ...

Signal transduction

... pathway. Signal amplification at the transmembrane hormone receptor A receptor that has been activated by a hormone can activate many downstream effector proteins. For example, a rhodopsin molecule in the plasma membrane of a retina cell in the eye that was activated by a photon can ...
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