... , an inflammatory disease of the bile duct , autoimmune
Primary biliary cirrhosis , autoimmune
disease of small bile ducts
Budd-Chiari ... , such as chronic hepatitis C, alcoholism, autoimmune
hepatitis, and many others. Less commonly, liver ...
... cell death. The survivors are tested as well for potentially damaging autoimmune
reactions, and those that show high affinity to healthy self antigen are ... a fundamental role in several human diseases, especially (but not only) in autoimmune
diseases, such as diabetes and multiple sclerosis.
Implication and ...
... in children and adolescents, but can occur in adults as well. It is an autoimmune
disorder , in which the body's own immune system attacks the beta cells ... them or damaging them sufficiently to reduce insulin production. The autoimmune
attack may be triggered by reaction to an infection, for example by one of ...
... immune system figures in a number of other disorders, particularly autoimmune
disorders such as lupus erythematosus , type I diabetes (sometimes ...
antigen /antigenic determinant / epitope / hapten / memory cell
CD4 receptor /CD8 receptor / perforin / apoptosis /clonal ...
... disease; malfunctions of the immune system in immunological disorders ( autoimmune
diseases , hypersensitivities , immune deficiency , allograft ... as HIV patients) and people suffering from other immune deficiencies or autoimmune
The specificity of the bond between ...
Detection of particular antibodies is a very common form of medical diagnostics. Serology depends on these menthods. autoimmune
disorders can often be traced to antibodies that bind the body's own epitopes; many can be detected through blood tests .
"Designed" monoclonal ...
... estrogens and progestagens (in the contraceptive pill and as HRT ), thyroxine (as levothyroxine , for hypothyroidism ) and steroids (for autoimmune
diseases and several respiratory disorders ). Insulin is used by many diabetics . Local preparations for use in otolaryngology often contain ...
Major histocompatibility complex
... duplicity creates a system of "checks and balances" and underscores the immune system's potential for running amok and causing harm to the body (see autoimmune
All Mhc molecules receive polypeptides from inside the cells they are part of and display them on the cell's exterior surface for ...
... . It often responds dramatically to glucocorticoids (e.g. prednisolone ).
Polymyositis , dermatomyositis and inclusion-body myositis are autoimmune
conditions in which the muscle is affected.
Rhabdomyolysis is the breakdown of muscular tissue due to any cause. While it may not lead to any ...
... that do not recognize them. Other T cells die by apoptosis (a small fraction actually survives but normally is controlled so it does not cause autoimmune
diseases). This process is called negative selection .
T cells go into apoptosis if they cannot express their TCR receptors, if they aren't ...