Navigation Links
CytRx Announces Clinical Results from Its Rising Multiple Dose,Trial with Arimoclomol for ALS

LOS ANGELES--(BUSINESS WIRE)--Jun 25, 2007 - CytRx Corporation (NASDAQ:CYTR), a biopharmaceutical company engaged in the development and commercialization of human therapeutics, today reported safety and tolerability results from its previously announced double-blind, placebo-controlled, rising multiple dose clinical trial in healthy volunteers with its drug candidate arimoclomol. CytRx believes that the results of this trial support the use of arimoclomol in future clinical trials, including its ALS Phase IIb clinical trial, at doses up to six-fold higher than that used in its previous Phase IIa clinical trials for ALS.

CytRx plans to begin its Phase IIb clinical trial in the second half of this year, subject to U.S. Food and Drug Administration (FDA) clearance. As previously announced, this trial, planned to include approximately 390 ALS patients enrolled at 30 to 35 U.S. and Canadian clinical sites, was designed to monitor changes in the progression of disease symptoms and would be completed about 18 months after the beginning of patient enrollment. Following consultation with the FDA, CytRx is now considering various options, including increasing the size and duration of the planned trial and/or conducting a second efficacy clinical trial for ALS, possibly in parallel with the Phase IIb trial, to provide additional data to support a possible approval decision by the FDA.

CytRx expects to announce results of its recently-completed six-month open-label extension trial with arimoclomol for ALS later this week.

"It is rewarding to see significant progress toward our goal of initiating the Phase IIb clinical trial for arimoclomol this year," stated CytRx's President and CEO Steven A. Kriegsman. "Based on the results of this clinical trial we plan to proceed with a dose that is four times greater than that used in our previous Phase IIa ALS clinical trials. These study results will help us optimize
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. CytRx Reports Promising Data from Its Open-Label Extension Clinical Trial of Arimoclomol in ALS
2. CytRx Announces RNAi Delivery Nanoparticle Technology Exclusively Licensed to Subsidiary, RXi Pharmaceuticals, Described in Peer-Reviewed Journal
3. CytRx Announces Positive Results of Arimoclomol in Preclinical Stroke Recovery Studies
4. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
5. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
6. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
7. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
8. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
9. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
10. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
11. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease

Post Your Comments:
(Date:11/6/2009)..., SARASOTA, Fla., Nov. 6 /PRNewswire-FirstCall/...nnounced that it has signed a definitive agreement...proprietary medical devices. The Verathon Board o...losing is subject to customary regulatory approval...proval. The parties expect the closing to be comp...
(Date:11/6/2009)..., CHARLESTON, S.C., Nov. 6 /PRNewswire-USNews...be stopping in South Carolina and Georgia througho...order to help uninsured and financially-struggling...ide prescription medicines for free or nearly free...10.2 percent, the Partnership for Prescription Ass...
(Date:11/6/2009)..., PRINCETON, N.J., Nov. 6 /PRNewswire-FirstCall... DSCI), a provider of advanced wound care products...9 results before market on Monday, November 16, 20...ame day to discuss the results at 11:00 am EST. In...tic) or (857) 350-1684 (international), with passc...
Breaking Medicine Technology:Roper Industries Announces Two Acquisitions to Enhance Growth in Medical and Toll & Traffic Businesses 2Roper Industries Announces Two Acquisitions to Enhance Growth in Medical and Toll & Traffic Businesses 3Partnership for Prescription Assistance Prepared to Help Southern Workers Hurt by Recession 2Partnership for Prescription Assistance Prepared to Help Southern Workers Hurt by Recession 3Derma Sciences Announces Date of Its Third Quarter 2009 Earnings Release and Conference Call 2Signatec Unveils PX14400 Its High Speed PCI Express Digitizer Capable of Sustained Recordings Over 1 2 GB s with Xilinx Virtex 5 FPGAs for Embedded R 14041 1Signatec Unveils PX14400 Its High Speed PCI Express Digitizer Capable of Sustained Recordings Over 1 2 GB s with Xilinx Virtex 5 FPGAs for Embedded R 14041 2Signatec Unveils PX14400 Its High Speed PCI Express Digitizer Capable of Sustained Recordings Over 1 2 GB s with Xilinx Virtex 5 FPGAs for Embedded R 14041 3Signatec Unveils PX14400 Its High Speed PCI Express Digitizer Capable of Sustained Recordings Over 1 2 GB s with Xilinx Virtex 5 FPGAs for Embedded R 14041 4Clalit Health Services Installs DBSophic 26apos 3Bs Database Performance Optimization Solution 57144 1Clalit Health Services Installs DBSophic 26apos 3Bs Database Performance Optimization Solution 57144 2Clalit Health Services Installs DBSophic 26apos 3Bs Database Performance Optimization Solution 57144 3Clalit Health Services Installs DBSophic 26apos 3Bs Database Performance Optimization Solution 57144 4Innovative New Book Series Encourages Kids to Go Behind Their Parents 26apos 3B Backs and Listen to Experts on Important Health and Wellness Educatio 57141 1Innovative New Book Series Encourages Kids to Go Behind Their Parents 26apos 3B Backs and Listen to Experts on Important Health and Wellness Educatio 57141 2Innovative New Book Series Encourages Kids to Go Behind Their Parents 26apos 3B Backs and Listen to Experts on Important Health and Wellness Educatio 57141 3Innovative New Book Series Encourages Kids to Go Behind Their Parents 26apos 3B Backs and Listen to Experts on Important Health and Wellness Educatio 57141 4Innovative New Book Series Encourages Kids to Go Behind Their Parents 26apos 3B Backs and Listen to Experts on Important Health and Wellness Educatio 57141 5
...stosterone Levels Throughout ...essed Satisfaction with NEBIDO, LEXINGTON, Mass.,...DEV ) today announced that data on NEBIDO(R),(test...ting intramuscular,injection for the treatment of ...entation at the 2008 American Urological Associati...
...day,announced that it has begun patient enrollment...cond PharmacoSurgery(TM) drug product candidate,fo...nts undergoing,unilateral ureteroscopic removal of...n the renal-collecting system or ureter will be en...Surgery(TM) product candidate into clinical,develo...
Other Medicine Technology:Indevus Presents Successful Phase III NEBIDO(R) Data at American Urological Association 2Indevus Presents Successful Phase III NEBIDO(R) Data at American Urological Association 3Indevus Presents Successful Phase III NEBIDO(R) Data at American Urological Association 4Omeros Announces Initiation of Patient Enrollment in OMS201 Phase 1 Study 2
(Date:11/7/2009)...IEGO, Nov. 7 The Public Relations Society of Amer...Fellow on Diane Gage Lofgren, senior vice presiden...ser Permanente, tonight at a ceremony at PRSA,s 20...ing inducted into the PRSA College of Fellows is o... said Michael Herman, APR, SAGE, Fellow PRSA, and ...
(Date:11/7/2009)... Forget ‘sweatox’ o...the UK is the usage of the anti-ageing jab ‘...en injected into the décolletage, can reduc...the chest area around the breasts, leaving smoothe... (PRWEB) November 7, 2009 -- Transform, the UK&rs...
(Date:11/6/2009)...ma endorses House health bill loaded with pledge-b...lowing was released today by Americans for Tax Ref...care bill today, President Barack Obama effectivel...ampaign was a lie. ,, During the campaign, Obama ...f taxes on families making less than $250,000 per ...
(Date:11/6/2009)...NGTON, Nov. 6 The U.S. bishops sent an urgent mes... 6, as House members steeped themselves in debate ... care reform bill. ,, Moments before meeting to di... called for "a fair process" that would permit dis...federal law on abortion funding and conscience pro...
(Date:11/6/2009)... A survey released today from J...sicians surveyed (74 percent) feel they have less ...hey did five years ago. , ...ey released today from Jackson Healthcare report...cent) feel they have less control over the way the...
Breaking Medicine News(10 mins):Health News:PRSA Inducts Head of Public Relations for Kaiser Permanente Into the College of Fellows for Contributions to the Profession and Lifetime Achievement 2Health News:PRSA Inducts Head of Public Relations for Kaiser Permanente Into the College of Fellows for Contributions to the Profession and Lifetime Achievement 3Health News:UK Boobs Get a Boost with 'Breastox' 2Health News:ATR: Obama Lied, His Tax Pledge Died 2Health News:ATR: Obama Lied, His Tax Pledge Died 3Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 2Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 3Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 4Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 5Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 2Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 3Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 4
...ndicated that doctors in the US U.S. doctors often... condition, leaving some patients to suffer for ye... infectious diseases in the world, and according t...t for years, and then can begin multiplying, espec...
...heir first FDA-approved tool to treat drug-resista...e University researcher.// "There are many tr... to combat drug resistance," said Arun Ghosh (pron... the first treatment that is effective against the...
...ggests that women with endometrial cancer should b... to a high risk of several other cancers.// ... 50, of newly diagnosed endometrial cancer patient...rome mutations are at high risk for colon, endomet...
... the risk of suffering a heart attack, according t...l of Medicine.The study is published// in the Augu...nd the full article is available on line at htt...ary heart disease could be at risk for heart attac...
... suppressor gene which was identified by Professor... Experiments done on this gene using the mice mod...o alters the ageing process. Larry Donehower of Ba... and the mice were protected against cancer but ag...
...he trail conducted by National Emphysema Treatment... benefited from surgery// that those who take medi...urgery (LVRS) to treat severe emphysema has result... years, two years longer than the primary results ...
Other Medicine News:Health News:Doctors In US Lack Skills For The Diagnosis Of TB 2Health News:Research Leads to First Treatment for Drug-Resistant HIV 2Health News:Research Leads to First Treatment for Drug-Resistant HIV 3Health News:Research Leads to First Treatment for Drug-Resistant HIV 4Health News:Uterine Cancer May be Clue to Inherited Syndrome 2Health News:Uterine Cancer May be Clue to Inherited Syndrome 3Health News:Risk Of Heart Attack Increased By Gout 2
Burton 2020 Lensmeter
...ing and innovative design, the Burton 7500-I refra... quality and masterful workmanship. At Burton, we ...a truly innovative concept, but to set the industr...ction and stringent testing, we devote more resour...
...et one of two memory positions to automatically re...return button, Durable upholstery, Elegant des... button control panel with three recharging wells,...ic counter-balanced slit lamp arm for easy, smooth...
2.5v Ophthalmic Diagnostic Set
Medicine Products: