Navigation Links
YM BioSciences Reports AeroLEF Randomized Phase IIb Trial Meets,Primary Endpoint in Patients with Post-Surgical Pain

MISSISSAUGA, ON, May 02, 2007 /PRNewswire-FirstCall/ - YM BioSciences Inc. , an oncology company that identifies, develops and commercializes differentiated products for patients worldwide, today announced top-line results from its randomized, placebo-controlled Phase IIb trial of AeroLEF(TM) in opioid naive patients with post-operative pain following orthopedic surgery. AeroLEF(TM) met the primary endpoint of the study, showing a statistically significant difference in SPRID4 from placebo (p=0.0194).

AeroLEF(TM) is a unique, inhaled-delivery composition of free and liposome-encapsulated fentanyl in development for the treatment of moderate to severe pain, including cancer pain. Unlike fixed dose approaches to opioid delivery, where a significant titration period is often required to determine the suitable dose for the patient, AeroLEF(TM) is being developed as a non-invasive patient self-titrated delivery system designed to enable patients to identify and select a personalized dose for each pain episode, achieving both rapid onset and extended duration of analgesia.

The trial evaluated the SPRID4 for AeroLEF(TM) compared with placebo for the treatment of the first pain episode. SPRID4 is a summary of the combined changes in pain relief and in pain intensity that patients report over the first 4 hours following initiation of dosing. The trial also examined a number of secondary endpoints including various measurements of pain relief, pain intensity, as well as onset and duration of analgesia, that are commonly used as indicators of efficacy for acute pain products. Various safety measurements were also examined.

"These results continue to demonstrate the unique potential for AeroLEF(TM) to be further developed into a valuable product for pain management across a broad range of indications, which could include post-operative pain, medical emergency pain and breakthrough pain," said David All
'"/>




Page: 1 2 3

Related medicine technology :

1. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
2. YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy
3. Sangamo BioSciences Announces Presentation of Phase 1 ZFP Therapeutic Data at American Diabetes Association Meeting
4. IR BioSciences Announces Promising Data from Study of Its Compound Homspera
5. Sangamo BioSciences Announces Presentation of ZFP Therapeutic Data From Nerve Regeneration Program at American Society for Neural Therapy and Repair Meeting
6. ImmuneRegen BioSciences Announces Promising Data on Homspera Suggesting Potential as a Co-Therapeutic Agent
7. Study in Cell by Magen BioSciences Co-Founder David E. Fisher Identifies New Roles in Skin Cancer Prevention for Key Tumor Suppressor Protein
8. IR BioSciences Announces Data Demonstrating Radilex Stimulation of Stem Cells Results in Hematopoietic Recovery Following Lethal Irradiation
9. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
10. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
11. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
Post Your Comments:
(Date:3/27/2015)... -- BioCorRx, Inc. ( BICX ... is a healthcare solutions organization, which focuses solely on addiction ... in the U.S. alone. The Company created a unique treatment ... specially compounded form for outpatient surgical implantation. The Company has ... New Zealand ) to the specially formulated Naltrexone ...
(Date:3/27/2015)... CHAPEL HILL, N.C. , March 27, 2015 /PRNewswire/ ... an intimidating job description: ensure products meet quality standards ... tight budgets and escalating regulations, quality leaders also have ... costs and risk. Those who don,t effectively ... quality function as well as marketplace failure and regulatory ...
(Date:3/27/2015)... Levi & Korsinsky announces it has commenced ... ) concerning possible violations of federal securities laws. The ... connection with its study of the drug OHR-102. To ... contact Joseph E. Levi, Esq. either via ... (212) 363-7500, toll-free: (877) 363-5972. Levi & ...
Breaking Medicine Technology:Small Cap IR Correction -- BioCorRx Inc. Positions Itself Through Strategic Partnerships To Gain Market Share Of The $22 Billion Substance Abuse Treatment Market In The U.S. 2New Medical Device Quality Study Finds Regulatory Environment is Boosting Quality Spending, Especially for Large Companies 2
... 2012  Hospira, Inc. (NYSE: HSP ), the world,s ... that the company will present at the Bank of America ... 2012, in Las Vegas. The presentation is scheduled ... 16, 2012. It will be available to all interested parties ...
... BOULDER, Colo., April 26, 2012 /PRNewswire-iReach/ ... management solutions, announces the availability of the Vending ... Fridge lets consumers use a simple QR code ... Mobile App to seamlessly purchase refrigerated products. The ...
Cached Medicine Technology:ShelfX Releases A Fridge That Knows What You Took 2
(Date:3/28/2015)... The California-based leading wig brand UniWigs has prepared ... UniWigs during the Easter Holidays from today until April ... April Fools’ Day. , As the winter fades and ... Easter Festival, with religious origins to countries in Europe ... Christmas. The best wig provider, UniWigs, would like to ...
(Date:3/28/2015)... March 28, 2015 Pitching speed, player’s height, ... of shoulder and elbow injuries, according to new research released ... AOSSM ) Specialty Day. , “Our findings indicate that a ... increase in likelihood of a history of injury, a 10 ... 12% increase likelihood of a history of injury, and playing ...
(Date:3/28/2015)... Genomic medicine experts have sequenced the genomes of ... time, key information for understanding and treating this intractable ... story on the Surviving Mesothelioma website. , ... British Columbia Cancer Agency, and PhenoPath lab in Seattle, ... and mutations that can lead to peritoneal mesothelioma ...
(Date:3/28/2015)... NV (PRWEB) March 28, 2015 ... new method of sustainable health. After 18 years of ... life, including professional UFC contenders, Dr. Jon Petrick is ... summer. , Just some of the immediate benefits of ... and vitality, increased levels of strength of the immune ...
(Date:3/28/2015)... Ontario (PRWEB) March 28, 2015 LTW ... have agreed to collaborate for the purpose of addressing ... technology venture will pursue its own opportunities to grow ... are part of LTW Cyber. , Ventures in LTW ... firmware, and complemented by offerings identifying vulnerabilities and analyzing ...
Breaking Medicine News(10 mins):Health News:UniWigs Is Sending Out Mysterious Gifts During the Easter Holidays 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:New Genomics Research May Help Doctors Tailor Mesothelioma Treatment, According to Surviving Mesothelioma 2Health News:Celebrity Chiropractor Jon Petrick to Release Sustainable Health System this Summer 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 3
... 900 persons in the Shangdong province of eastern China have ... outbreak has since been contained, state news agency Xinhua ... Friday last and another 393 people mostly children ... hospital, the agency said, citing Bao Wenhui, the deputy director ...
... attempts to curb a remorselessly exploding population, the government of ... for some time, like the one child norm. ... is aimed at controlling population growth in the world's biggest ... urban dwellers to have one child, while villagers can have ...
... to official statistics from Singapore, the tropical city-state ... dengue infections in the first trimester of this year compared ... the start of January to May 12 rose to 1,488, an ... Ministry of Singapore was quoted. ,Experts cite this figure ...
... autism rate in America, have pushed toward law proposals to promote ... the disorder. A recent U.S. study of childhood autism, the largest ... disorder, with the highest rate 1 in 94 children ... Goldfarb, a Livingston mother of a 13-year-old autistic son, a crisis ...
... may be used to diagnose the severity of asthma in ... the Netherlands conceived the device. ,The device, which ... used in the food, wine and perfume industries, contains chemical ... compounds, or VOCs, in a persons exhaled breath. ...
... the male impotence drug Viagra may be useful for ... for the treatment of high blood pressure and angina, ... of a naturally-occurring compound, cyclic guanine monophosphate (cGMP). ... in a signalling pathway that regulates the circadian cycle, ...
Cached Medicine News:Health News:Aggressive Family Planning Sparks Riots in China 2Health News:Figures of Dengue In Singapore On The Rise 2Health News:American State Lawmakers Make Moves To Tackle Autism 2Health News:Electronic Nose to Diagnose the Severity of Asthma 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: