Navigation Links
XYOTAX More Cost Effective With Fewer Side Effects Than Gemcitabine,or Vinorelbine in Treating Non-Small Cell Lung Cancer

ts on XYOTAX had longer median survival (220 days vs. 198 days; p=0.686) with significantly fewer adverse events (all grades; 2.0 vs. 3.0; p=0.011), despite receiving more chemotherapy cycles (3.9 vs. 3.4; p=0.007). In addition, XYOTAX patients had fewer outpatient visits (0.6 vs. 1.7; p < 0.001), required fewer diagnostic tests (0.6 vs. 1.9; p < 0.001), and were on non-chemotherapy medications for a shorter period of time (64.4 days vs. 91.2 days; p < 0.001). The difference in the number of hospitalizations or length of hospital stays was not statistically significant.

The total average cost of treatment reported, excluding drug costs, was lower for XYOTAX patients ($2,518 per patient) than patients on the control arm ($4,834 per patient). Costs included outpatient visits ($34 vs. $78; p=0.014), non-chemotherapy medications ($717 vs. $911; p < 0.001), chemotherapy administration ($1,557 vs. $3,601; p < 0.001), and in-patient stays ($210 vs. $244; p=0.794) per patient.

About XYOTAX

XYOTAX(TM) (paclitaxel poliglumex) is a biologically-enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable polyglutamate polymer, which results in a new chemical entity. When bound to the polymer, the chemotherapy is rendered inactive, potentially sparing normal tissue's exposure to high levels of unbound, active chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like polyglutamate. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy. Based on preclinical studies, it appears that XYOTAX is preferentially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Preclinical and clinical studies support that XYOTAX metabolism by lung cancer cells m
'"/>




Page: 1 2 3 4

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
3. Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
4. Gabapentin Shown Effective for Fibromyalgia Pain
5. ApoCells Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
6. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
7. Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
8. Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and Effective in Colorectal Cancer with Liver Metastases
9. Biotheras Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
10. Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
11. In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression
Post Your Comments:
(Date:10/2/2014)... Oct. 2, 2014   West Pharmaceutical Services, Inc. ... in innovative solutions for injectable drug administration, announced today ... include a new site in Waterford, Ireland ... for insulin injector cartridges and other high-value packaging components, ... biotech customers. Once operational, this new site could bring ...
(Date:10/1/2014)... DUBLIN, Ohio , Oct. 1, 2014 ... to shareholders is now available. Interested parties can ... and how Cardinal Health is supporting the ... at http://cardinalhealth.com/annualreport . Photo- ... addition to summary financials and the chief ...
(Date:10/1/2014)... 1, 2014  ResMed (NYSE: RMD ), a ... company to design complete sleep apnea solutions specifically for women, ... importance of a good night,s sleep. The ... that feeling tired is just part of living a busy ... a critical pillar of health, essential to not only living ...
Breaking Medicine Technology:West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 2West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 3West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 4West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 5Cardinal Health 2014 Digital Report to Shareholders Now Available 2ResMed Launches Initiative to Help Women Get Better Sleep 2ResMed Launches Initiative to Help Women Get Better Sleep 3
(Date:10/2/2014)... Originally considered alternative food only ... increasingly popular with consumers. This has fuelled demand ... industry in Australia. According to IBISWorld industry ... has surged over the past five years, contributing ... level.” Over the five years through 2014-15, industry ...
(Date:10/2/2014)... Maureen Salamon HealthDay ... -- Middle-aged women with a neurotic personality style and ... Alzheimer,s disease, new research suggests. Tracking 800 women ... who were most anxious, jealous and moody -- which ... had double the risk of developing Alzheimer,s compared to ...
(Date:10/2/2014)... (HealthDay News) -- Children with autism are more sedentary ... of being more active, a small study suggests. ... children, some with autism and some without. Children with ... physical activity and 70 more minutes each day sitting ... autism scored lower on strength, but had similar body-mass ...
(Date:10/2/2014)... Amy Norton HealthDay Reporter WEDNESDAY, ... smelling the roses -- literally -- may face an increased risk ... In a study of over 3,000 older Americans, researchers found those ... peppermint were more than three times as likely to die in ... smell. In fact, anosmia -- the inability to distinguish odors ...
(Date:10/2/2014)... medical discovery by scientists at The University of Nottingham ... type of painkiller. , A drug resulting from the ... , would offer new hope to sufferers of chronic ... few effective painkillers are currently available. , The work, ... of Life Sciences, in collaboration with David Bates, Professor ...
Breaking Medicine News(10 mins):Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 2Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 3Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 4Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 2Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 3Health News:Kids With Autism Tend to Be Less Active, Study Says 2Health News:Could a Fading Sense of Smell Point to Earlier Death? 2Health News:Could a Fading Sense of Smell Point to Earlier Death? 3Health News:Medical discovery first step on path to new painkillers 2
... PhD, president of The J. David Gladstone Institutes, ... The award recognizes his leadership as Gladstone,s founding ... one of the world,s foremost independent research institutions, ... impact on disease prevention. Mahley will be ...
... ... regarding 2010 Shanghai, China Expo -- attracting attention from all walks of life. , ... Beijing (PRWEB) February 10, 2010 -- ... biggest World Expo in the history of world expositions. , , ,This special tour has ...
... women don,t know it is leading killer, survey finds , ... almost half of all American women still don,t know that ... new research finds. , Even more concerning, only slightly more ... they were having heart attack symptoms, according to the latest ...
... with Inflammatory Bowel Disease (IBD) are known to be at high ... of their disease but now new research by scientists at The ... to hospital during flare-ups are also at risk. The two ... affect about one in every 250 people in the UK. The ...
... ... to learn how to differentiate from competition and manage risk. , ... Lafayette, CO (PRWEB) February 10, 2010 -- Auto dealers will be able ... lead-generation, HR best practices and OSHA regulations at the Orlando NADA Convention and Expo 2010., , ...
... Poll Finds Voters Prefer Tobacco Tax to Other Tax Increases, Budget Cuts ... Utah ,s cigarette tax by $1 per pack would bring ... the state,s budget shortfall, while also reducing smoking and saving lives, according ... organizations.  In Utah, health advocates are calling on state leaders to increase ...
Cached Medicine News:Health News:Gladstone's Robert Mahley to receive Research!America advocacy award 2Health News:Jion Beijing Great Wall International Travel Agency Immediate Exposure to China Expo 2010 2Health News:Women's Heart Disease Awareness Still Lacking 2Health News:Women's Heart Disease Awareness Still Lacking 3Health News:Bowel disease link to blood clots 2Health News:Bowel disease link to blood clots 3Health News:KPA and TK Carsites offer HR, OSHA and Internet Marketing Workshops at the NADA Convention and Expo 2010 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $43.3 Million for Utah and Cut Youth Smoking 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $43.3 Million for Utah and Cut Youth Smoking 3
It provides excellent illumination from an inexpensive platform and is mounted on the comfortable UltraLite headband....
It is a fiberoptic based intracranial monitoring systems for continuous monitoring of pressure....
... The Polaris system delivers the most ... effective and easy to use, this ... of precision measurement with unprecedented tracking ... active and passive tools, the Polaris ...
Penfield Dissector #2...
Medicine Products: