Navigation Links
Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA,Nanoparticles

CLEVELAND--(BUSINESS WIRE)--Jun 4, 2007 - Copernicus Therapeutics, Inc. announced today that a research team at University of Oklahoma Health Sciences Center, led by Dr. Muna Naash, Professor of Cell Biology, demonstrated that Copernicus' DNA nanoparticles corrected vision defects in a mouse model of retinitis pigmentosa (RP). These findings were presented at the American Society of Gene Therapy meeting in Seattle, WA. Mutations in genes important in the biology of vision cause RP, a common genetic form of visual impairment affecting nearly 70,000 patients in the United States.

"These exciting results demonstrate that delivery of normal copies of genes into photoreceptor cells can correct vision defects in RP," said Mark Cooper, M.D., Senior Vice President of Science and Medical Affairs. "In addition to the promise of providing corrective therapy for genetic diseases such as retinitis pigmentosa, nucleic acid nanoparticles may also offer the potential to provide effective treatments for more complex disorders such as diabetic retinopathy, macular degeneration, and various diseases that injure ganglion cells and the optic nerve."

"We are pleased by the promise of these results and look forward to moving these studies forward to a potential human clinical trial," said Dr. Naash.

"Gene therapy holds great potential for treating and possibly curing a variety of vision-robbing retinal degenerative diseases," says Stephen Rose, Ph.D., Chief Research Officer, Foundation Fighting Blindness. "Dr. Naash and Copernicus are demonstrating that nanoparticles show excellent potential for safely and effectively delivering therapeutic genes to the retina." Dr. Naash's work was funded in part by the Foundation Fighting Blindness.

About Copernicus, the University of Oklahoma and the Foundation Fighting Blindness

Copernicus Therapeutics, Inc., a privately held biotechnology company, is dedicated to deli
'"/>




Page: 1 2

Related medicine technology :

1. OXiGENE Announces a Poster Presentation Highlighting Results from its Study of ZYBRETSTAT CA4P in Myopic Macular Degeneration (Study MMD-213) at the 47th Annual Meeting of the Association of Research in Vision and Ophthalmology
2. Isotechnikas Lead Drug, ISA247, To Be Highlighted at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
3. Inspire Announces Presentations at 2007 Association for Research in Vision and Ophthalmology Annual Meeting
4. Sirion Therapeutics Announces Clinical Data to be Presented at the 2007 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
5. Advanced Cell Technologys Ability to Rescue Vision in Blind Rats Noted in Scientific American
Post Your Comments:
(Date:7/25/2014)... -- Smile Train and its technology partner BioDigital have been ... among leading global health innovations in The Hive at ... Washington, D.C. at The John F. Kennedy ... Train is honored to be represented through our partnership ... health and medicine that TEDMED unites each year," said ...
(Date:7/25/2014)... -- CVS Caremark Corporation (NYSE: CVS ) will ... 2014, at 8:30 a.m. (EDT) with analysts and investors ... An audio webcast of the conference call will ... the CVS Caremark website for all interested parties.  To ... will be archived and available on the web site ...
(Date:7/25/2014)... Cardinal Health will today name three of the nation,s ... Independent Pharmacy Best Practices Competition, during the company,s ... gatherings of independent pharmacists. The Best ... Ohio , Tennessee and ... implementing exceptionally creative methods that demonstrate how independent pharmacies ...
Breaking Medicine Technology:Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 3Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 2Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 3Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 4Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 5Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 6
... 1, 2012  Ultragenyx Pharmaceutical Inc., a biotechnology company ... genetic disorders, today announced results from a first-in-human, ... with hereditary inclusion body myopathy (HIBM) showing that ... profile on absorption after oral administration.  UX001 is ...
... (OTC Bulletin Board: NWBO ) (NW Bio) today announced ... received approval of a major grant from the Sachsische Aufbau ... will reimburse fifty percent (50%) of the costs for manufacturing ... for brain cancer at up to ...
Cached Medicine Technology:Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease 2Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease 3Northwest Bio Awarded $5.5 Million German Government Grant 2Northwest Bio Awarded $5.5 Million German Government Grant 3Northwest Bio Awarded $5.5 Million German Government Grant 4
(Date:7/26/2014)... Another DePuy Pinnacle hip lawsuit against Johnson & Johnson ... Wright & Schulte LLC. This DePuy Pinnacle hip ... County, Ohio man who alleges that he has had pain ... his Pinnacle Hip implant in 2008. According to this hip ... a complex and risky revision surgery to replace the metal-on-metal ...
(Date:7/26/2014)... (PRWEB) July 26, 2014 According to ... Vkool.com, this is a comprehensive guide that covers detailed ... (KP) effectively without the need of any medication. ... consists of natural and safe remedies for relieving symptoms ... people will learn:,     How to treat ...
(Date:7/26/2014)... The birth control safety center at DrugNews.net is ... legal information on the site. A federal panel recently ... pending for July alleging side effects from the device*. ... popular prescription drugs and medical devices. By giving patients ... all in one place, they can see if others ...
(Date:7/25/2014)... Dallas, Texas (PRWEB) July 26, 2014 ... Global and China Gel Permeation Chromatography Industry” ... on the Global and China Gel Permeation ... Permeation Chromatography information, including Gel Permeation Chromatography ... as well as industry overview. This research ...
(Date:7/25/2014)... July 26, 2014 According to ... Market by Product (vibration monitoring, thermography, ultrasound emission, ... analysis), Component, Application and Geography - Global Forecast ... machine health monitoring market is expected to reach ... to 2020. , Browse 117 market data Tables ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Recipient Who Faces Surgery To Replace Artificial Hip Implant 2Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Recipient Who Faces Surgery To Replace Artificial Hip Implant 3Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Recipient Who Faces Surgery To Replace Artificial Hip Implant 4Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Recipient Who Faces Surgery To Replace Artificial Hip Implant 5Health News:Banish My Bumps Pdf Review Exposes Angela Steinberg's Keratosis Pilaris Treatment Plan – Vkool.com 2Health News:Banish My Bumps Pdf Review Exposes Angela Steinberg's Keratosis Pilaris Treatment Plan – Vkool.com 3Health News:DrugNews Adds Latest Court Updates on Mirena IUD Lawsuits 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 3Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 2Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 3Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 4
... of Illinois at Chicago have discovered a possible target ... can invade the bloodstream, which can lead to severe ... 750,000 people affected in the United States each year, ... Care Medicine. , "The growth of bacterial pathogens in ...
... study provides valuable insight into a previously undescribed ... research, published by Cell Press in the February ... of the fundamental processes that contribute to breast ... receptor coactivator-3 (SRC-3/AIB1) plays key roles in cell ...
... Rutgers have unlocked some of the mysteries of how ... of vitamin A present in the maternal blood stream. ... of the Journal of Biological Chemistry. , The ... facilitates the formation of vitamin A stores in the ...
... Seventh Annual American Red Cross National Celebrity Cabinet ... Cross Initiatives, WASHINGTON, Feb. 28 The ... Cabinet with fifteen new,members, Emmy Award winner Patricia ... Garth, actor Masi Oka, pro skateboarder Tony Hawk, ...
... people to stay active, helps reduce arthritis ... pain through ... today a,partnership with McNeil Consumer Healthcare, the maker of TYLENOL(R),Arthritis Pain, ... reduce arthritis pain. Through this new collaboration,participating YMCAs will introduce members ...
... The Geriatric Oncology,Consortium ("The GOC") announced today that ... to the Tampa Bay area., The GOC, a ... and educational network of Oncology healthcare,providers with a mission ... raise awareness and funds for this effort, the GOC ...
Cached Medicine News:Health News:Researchers find possible target to treat deadly bloodstream infections 2Health News:Atypical protein kinase C stabilizes SRC-3 levels in breast cancer cells 2Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 2Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 3Health News:Celebrities Join the American Red Cross in 2008 to Help Change Lives 2Health News:Celebrities Join the American Red Cross in 2008 to Help Change Lives 3Health News:Celebrities Join the American Red Cross in 2008 to Help Change Lives 4Health News:YMCA of the USA and McNeil Consumer Healthcare Partner to Promote Health for Older Adults 2Health News:YMCA of the USA and McNeil Consumer Healthcare Partner to Promote Health for Older Adults 3Health News:Geriatric Oncology Consortium (GOC) Announces Tampa Bay Road Rally to Raise Awareness for the Treatment of Seniors With Cancer 2
... the use of sand bags under the drape during ... shaped for optimal foot contact and positioning the leg ... be used under the drape by attaching it to ... for use on top of the drape. It can ...
... for trauma, foot and ankle or deformity ... External Fixation components are designed to reduce ... the complexity of intra-operative and post-operative frame ... and hinges eliminate the need to stock ...
... The Bio-Post and Washer System offers ... or soft tissue fixation in ligament repair ... and cancellous screw design provide maximum fixation ... length can be intraoperatively determined and the ...
... True/Flex Upper Extremity Intramedullary Rod System offers ... to conventional methods of rodding and plating. ... at the fracture site and enhanced healing4 ... to be easily inserted into the canal. ...
Medicine Products: