d using well-established bacterial fermentation and
purification technology. After a plasmid is delivered into muscle
or tumor cells, production of the desired antigens may then induce
a preventive or therapeutic immune response against the targeted
disease. Inovio's advanced electroporation devices facilitate
delivery and expression of these plasmid DNA-based
immunotherapeutics and have been shown in primate studies and
interim Phase I data to significantly enhance antibody and T-cell
immune responses over plasmid DNA delivered by other methods,
suggesting the potential to provide a better protective or
therapeutic effect against complex infectious diseases as well as
cancers.
Inovio is poised to deliver advanced DNA-based immunotherapies,
devices and know-how in this rapidly advancing field. The company
is actively licensing its technology to pharmaceutical and
biotechnology companies and supporting early stage clinical studies
arising from its own research efforts or through academic
collaborations.
About Inovio Biomedical Corporation
Inovio Biomedical (AMEX:INO) is focused on developing multiple
DNA-based immunotherapies and commercializing its Selective
Electrochemical Tumor Ablation (SECTA) therapy. Inovio is a leader
in developing human applications of electroporation, which uses
brief, controlled electrical pulses to increase cellular uptake of
a useful biopharmaceutical. In the case of DNA vaccines, Inovio's
technology has shown it can significantly increase levels of gene
expression and immune response. Inovio's immunotherapy partners
include Merck, Wyeth, Vical, University of Southampton, Moffitt
Cancer Center, and the U.S. Army, with four DNA-based
immunotherapies in Phase I clinical studies. The SECTA therapy for
locally treating solid tumors is designed to selectively kill
cancerous cells and minimize cosmetic or functional detriments
often caused by surgical removal of predominantly healthy tissue
typically treated around a tumor.
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Page: 1 2 3 4 5 Related medicine technology :1.
Vical Licensee AnGes MG Announces Positive Results of Phase 3
Angiogenesis Trial in Japan2.
Vicals Vaxfectin Adjuvant With Needle-free Delivery Enhances DNA
Vaccine Performance; Yields Antibody Responses Comparable to
Electroporation Without Tolerability Issues3.
Vicals Vaxfectin Adjuvant Achieves Dose-Sparing Effect With
Seasonal Influenza Vaccine4.
Cell Therapeutics, Inc. Management to Discuss Todays Announcement
of Interim Pixantrone Study Results5.
Positive ZIO-201 Interim Phase II Sarcoma Data Presented at
European Society for Medical Oncology6.
Ablynx Announces Interim Results of First Nanobody Phase I Study of
ALX-0081 (ANTI-VWF)7.
Based on Up to 6 Years of Follow-Up, Biovest Announces Favorable
Interim Blinded Data for Fast-Tracked Pivotal Phase 3 Clinical
Trial of BiovaxID Anti-Cancer Vaccine for Non-Hodgkins Lymphoma8.
ZIO-101 (Darinaparsin) Interim Phase II and Preclinical Data
Presented at International Myeloma Workshop9.
Accentia Biopharmaceuticals Announces Favorable Interim Blinded
Data on SinuNase in Its Fast-Tracked Pivotal Phase 3 Clinical Trial
for Chronic Sinusitis10.
Pharmacyclics Announces Interim Results From Two Ongoing Phase 2
Trials Supporting Potential of Xcytrin Plus Chemotherapy to Treat
Recurrent Non-Small Cell Lung Cancer11.
Interim Analysis of Crinone Pregnancy Study to Be Published in
American Society for Reproductive Medicine Journal