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Vertex Pharmaceuticals Announces New Data for Investigational HCV,Protease Inhibitor Telaprevir to be Presented at 42nd Annual,Meeting of the European Association for the Study of the Liver,(EASL)

mercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is focused on viral diseases, inflammation, autoimmune diseases, cancer, pain and bacterial infection. Vertex co-discovered the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.

Vertex's press releases are available at www.vrtx.com.

About Tibotec

Tibotec Pharmaceuticals Ltd., based in Cork, Ireland, is a pharmaceutical research and development company. Tibotec is dedicated to the discovery and development of innovative HIV/AIDS drugs and anti-infectives for diseases of high unmet medical need. The Company's main research and development facilities are in Mechelen, Belgium with offices in Yardley, PA.

For further information on Tibotec, please visit: www.tibotec.com

Safe Harbor Statement

This press release may contain forward-looking statements, including statements that (i) non-clinical, in vitro studies evaluating telaprevir against NS3 4A proteases in patients with genotype 2, 3 and 4 support Vertex's planned clinical evaluation of TVR in other genotypes; (ii) viral kinetic data will continue to support further evaluation of telaprevir combination therapy to clear the virus with shorter treatment duration; (iii) in vivo and in vitro viral replication and viral sequencing dynamic modelling studies suggest that telaprevir-resistant variants have reduced replication capacity compared to wild-type HCV; and (iv) Vertex expects the combined PROVE program to increase to more than 1,000 the number of patients in telaprevir clinical trials. While management makes its best efforts to be accurate in making forward-looking statements, such statements are subject to risks and uncertainties that could cause the actual results of studies to vary materially. Those risks and uncertainties include, among other things, the risk that observed outcomes in in vitro analyses or in clinical investigations of small num
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