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Vaccine Can Prevent Cervical Cancer and Precancerous Lesions

gh these interim efficacy data are encouraging, their interpretation has limitations. The follow-up was brief, given that cervical carcinogenesis often evolves over several decades. They also highlight increases in adverse reactions among women in the HPV vaccine group.

Finally, the Comment authors raise the issue of ensuring the vaccine is distributed in the developing world, where cervical cancer makes the largest contribution to years of life lost to cancer, concluding: "Poverty is strongly associated with high-risk HPV infection and cervical cancer. If those who live in poverty cannot access a highly effective intervention such as HPV vaccines, disparities could worsen dramatically."

Professor Jorma Paavonen, Department of Obstetrics and Gynaecology, University of Helsinki, Finland. T) +35 8400497900

Comment Dr Jessica Kahn, Cincinnati Children’s Medical Center, University of Cincinnati College of Medicine, USA. T) +1 513 636 8587

Jorma.Paavonen@hus.fi

Jessica.kahn@cchmc.org


pressoffice@lancet.com
Telephone: +44 (0)20 7424 4949/4249
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