Navigation Links
Updated Overall Survival Data From Pivotal Herceptin Adjuvant,Studies in HER2-Positive Breast Cancer

lude, in the product label, data that showed an improved median overall survival for women with HER2-positive metastatic breast cancer treated initially with Herceptin and chemotherapy, compared to chemotherapy alone (median 25.1 months compared to 20.3 months).

In November 2006, Herceptin was FDA-approved as part of a treatment regimen containing doxorubicin, cyclophosphamide, and paclitaxel for the adjuvant treatment of HER2-positive, node-positive breast cancer based on results that showed Herceptin reduced the risk of cancer recurrence by 52 percent. Adjuvant therapy is given to women with early-stage (localized) breast cancer who have had initial treatment -- surgery with or without radiation therapy -- with the goal of reducing the risk of cancer recurrence and/or the occurrence of metastatic disease.

There are now four studies in the adjuvant setting demonstrating that the addition of Herceptin to a chemotherapy regimen increased disease-free survival for women with early-stage HER2-positive breast cancer. Nearly 400,000 women have been treated with Herceptin worldwide since its first approval in 1998.

Herceptin Safety Profile

Herceptin administration can result in left ventricular dysfunction and congestive heart failure (CHF). The incidence and severity of left ventricular cardiac dysfunction/CHF were highest in patients who received Herceptin concurrently with anthracycline-containing chemotherapy regimens. Physicians should discontinue Herceptin treatment in patients receiving adjuvant therapy for breast cancer and strongly consider discontinuation of Herceptin in patients with metastatic breast cancer who develop a clinically significant decrease in left ventricular function.

Patients receiving Herceptin should undergo frequent monitoring for deteriorating left ventricular function. More frequent monitoring should be employed in patients with preexisting cardiac dysfunction receiving Herceptin. Monitoring will not ident
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Infinity and MedImmune Present Updated Phase I Results of IPI-504 in GIST at ASCO Annual Meeting
2. Updated Study Results Reinforce Survival Benefit of Taxotere (Docetaxel) for Men with Advanced, Hormone-Resistant Prostate Cancer
3. Introgen Reports Updated Phase 2 Advexin Data Correlating Improved Survival, Tumor Responses and Predictive p53 Biomarker
4. Vion Pharmaceuticals Presents Updated Clinical Data from a Phase II trial of Cloretazine (VNP40101M) in Patients with Relapsed or Refractory Small Cell Lung Cancer
5. Infinity and MedImmune Announce Updated Data On Ipi-504 to be Presented At ASCO
6. Avanir Pharmaceuticals Presents IEED Prevalence and Updated Zenvia Long-Term Safety Data at AAN Annual Meeting
7. Media Advisory: ACC Updated Schedule
8. Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival
9. Phase IIIb Clinical Data Validate the Overall and Cardiovascular Safety Profile of Cycloset (A Quick Release Formulation of Bromocriptine Mesylate) in Patients with Type 2 Diabetes
10. Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal Women with Early Breast Cancer Receiving Treatment with Tamoxifen
11. Synta Presents Results for STA-4783 in Metastatic Melanoma Showing Improvement in Overall Survival
Post Your Comments:
(Date:8/29/2014)... Mass. , Aug. 29, ... PHG AEX: ... the  European Society of Cardiology ... is highlighting the full range of its cardiology solutions serving ... care continuum from prevention and diagnosis, ...
(Date:8/28/2014)... Aug. 28, 2014 Reportlinker.com announces that ... its catalogue: North America Aesthetic Lasers ... http://www.reportlinker.com/p02343466/North-America-Aesthetic-Lasers-and-Energy-Devices-Market-Outlook-to-2020.html North ... to 2020 Summary GlobalData,s new report, ... Outlook to 2020", provides key market data on ...
(Date:8/28/2014)... 28, 2014  Rigrodsky & Long, P.A.: , ... (NYSE: LCI )? , Did you purchase your ... July 16, 2014, inclusive? , Did you lose money ... you want to discuss your rights? ... Attorney, Timothy J. MacFall , announces that a complaint has ...
Breaking Medicine Technology:Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 2Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 4Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 5North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 2North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 3North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 4North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 5North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 6North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 7North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 8North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 9North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 10North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 11North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 12North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 13North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 14North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 15North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 16Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 3
... fourth quarter 2011 earnings release (expected to be issued after ... CVD ) is pleased to invite you to listen ... live over the Internet on Thursday, January 26, 2012 at ... , , Covance Fourth Quarter 2011 Earnings Webcast and Slide ...
... 2012  Yesterday, workers at VPH Pharmacy, a non-retail, pharmaceutical ... the United Food and Commercial Workers (UFCW) Union in ... on the job. The vote ends the workers, nearly ... they stood unmoved and united in their fight. ...
Cached Medicine Technology:
(Date:8/29/2014)... 29, 2014 Recent reports, backed by ... Americans today are working longer hours and taking fewer ... APEC Water believes that drinking lots of purified water ... Sale on their most popular and effective water purification ... now until 9/2/2014, customers can save up to $125 ...
(Date:8/29/2014)... Under Section 946.300, Qualifications for the Certifying Physician, it ... in a cultivation center or a dispensing organization.” What ... Illinois has done is create a level of transparency ... care. The goal is to create a level of ... prescription medications. Medical steering is a serious issue in ...
(Date:8/28/2014)... VPS (Virtual Private Server) is the method ... servers, each of which has the appearance and ... Top10BestSEOHosting.com has recently compared many professional web hosting ... Bluehost and IX Web Hosting are the best ... manager of Top10BestSEOHosting.com says, “These companies have outperformed ...
(Date:8/28/2014)... Doctors Frank DellaCroce and Scott Sullivan, Co-Founders ... (CRBS) and the St. Charles Surgical Hospital (SCSH) ... board certified surgeon Dr. Craig Ashley Blum has joined ... reconstructive breast surgery. Blum will work with the team ... and M. Whitten Wise. , “We are excited to ...
(Date:8/28/2014)... August 28, 2014 Starting on Monday, ... is able to accept donations in Bitcoin, in addition ... donation page can be found at http://www.curemeso.org/bitcoin . ... Bitcoin as a form of payment, we decided it ... Meso Foundation’s chief executive officer, Melinda Kotzian. , ...
Breaking Medicine News(10 mins):Health News:Relax this Labor Day Weekend with Great Savings on Easy-Install, Do-It-Yourself Drinking and Whole House Water Filters 2Health News:Medical Marijuana Company Provides Solution for Illinois Marketing Regulations 2Health News:Top10BestSEOHosting.com Announces The Best Three VPS Hosting Suppliers 2Health News:New Plastic Surgeon Joins Center For Restorative Breast Surgery 2Health News:Cancer Research Funding Organization Now Accepts Bitcoin Donations 2
... Nov. 11 Anthem Blue Cross and,Blue Shield in ... 239 health,insurance plans, according to the current (Nov. 17) ... Plans 2008-09. This recognition as,one of the nation,s best ... clinical care measures, member satisfaction and NCQA,accreditation., "We ...
... Revolution in Thermotherapy, ALAMEDA, Calif. and PITTSBURGH, ... announced today the introduction of ReBound, a new ... muscle,spasms, and joint contractures using radio frequency (RF) ... injury treatment systems,to the physical therapy and athletic ...
... not enough outreach and prevention, new report finds , , ... training, a lack of educational materials, and meager data ... dangers of drowsy driving in the United States and ... The National Sleep Foundation (NSF) released its findings Tuesday ...
... YORK, Nov. 11 Today, the Association ... results of a,nationwide survey on the incidence ... APIC failed to connect the dots,",says Betsy ... Reduce Infection,Deaths (RID). "The new data show ...
... Study Finds 73% Are From Health Care Facilities, ... on hospitals today to take more aggressive steps ... light of a new report,showing that they are ... the rate of hospital acquired C.-diff. infections has ...
... Nov. 11, 2008 Researchers at UT Southwestern Medical ... Mr. Hyde" nature of a protein that stimulates stem-cell maturation ... damage. , In two separate studies in mice scheduled ... of the Proceedings of the National Academy of Sciences ...
Cached Medicine News:Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 2Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 3Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 4Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 5Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 6Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 7Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 8Health News:Anthem Blue Cross and Blue Shield in Maine Among Top Insurers on U.S. News & World Report/National Committee for Quality Assurance America's Best Health Plans List 9Health News:Game Ready(TM) and ReGear Life Sciences(TM) Bring Innovative New Heat Therapy to Market 2Health News:Game Ready(TM) and ReGear Life Sciences(TM) Bring Innovative New Heat Therapy to Market 3Health News:States Asleep at the Wheel in Fighting Drowsy Driving 2Health News:APIC Covers Up Extent and Causes of Deadly C. diff 2Health News:New Report Shows High C-difficile Infection Rates in U.S. Hospitals 2Health News:New Report Shows High C-difficile Infection Rates in U.S. Hospitals 3Health News:New Report Shows High C-difficile Infection Rates in U.S. Hospitals 4Health News:Protein can nurture or devastate brain cells, depending on its 'friends,' researchers find 2Health News:Protein can nurture or devastate brain cells, depending on its 'friends,' researchers find 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: