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Ulcerative Colitis (UC) Sufferers Find UC Quite Disruptive to Many,Aspects of Daily Life

ilic and lipophilic excipients.

LIALDA has only been studied in UC, not in areas outside of UC such as depression or stress. Patients should discuss these conditions with their health care providers.

Shire has licensed from Giuliani SpA the exclusive rights to develop and commercialize LIALDA in the U.S., Canada, Europe - known as MEZAVANT(TM) - (excluding Italy) and the Pacific Rim. Giuliani SpA retains the development and commercialization rights in Italy. Cosmo Pharmaceuticals SpA, Milan, developed the MMX technology.

Important Safety Information for LIALDA

Lialda is approved for the induction of remission in patients with active, mild to moderate ulcerative colitis. Safety and efficacy of Lialda beyond eight weeks have not been established.

You should not take Lialda if you are allergic to mesalamine or other salicylates (such as aspirin), or to any of the other ingredients in Lialda. Tell your doctor if you have a stomach blockage or are allergic to sulfasalazine. Mesalamines have been associated with an acute intolerance syndrome, a condition that may be difficult to distinguish from a flare of UC. Tell your doctor if you experience symptoms such as abdominal pain, cramping, bloody diarrhea, headache, and rash. Some patients taking mesalamines have reported heart-related hypersensitivity reactions, such as inflammation of the heart muscle and inflammation of the lining of the heart. Tell your doctor if you have problems with your liver or kidneys.

Lialda is generally well tolerated. In worldwide clinical trials, the most common adverse events were headache and flatulence. As with other medications, some serious side effects may occur. While taking Lialda, visit your doctor periodically. If you have any questions about Lialda, please talk to your doctor.

Important Safety Information for PENTASA

PENTASA is approved for the induction of remission and for the treatment of mildly to moderately active ulcerativ
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