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UCB Announces Positive Top-Line Phase III Results for Keppra as,Adjunctive Therapy for Partial Onset Seizures in Paediatric,Patients from One Month to Less than Four Years of Age

irable effects were somnolence, asthenia and dizziness. As adjunctive therapy in paediatric patients (4-16 years of age) with partial onset seizures the most commonly reported undesirable effects were somnolence, hostility, nervousness, emotional lability, agitation, anorexia, asthenia and headache. In adults and adolescents with myoclonic seizures the most common reported undesirable effects associated with Keppra® in combination with other AEDs were headache and somnolence. In adults and adolescents with primary generalized tonic-clonic seizures the most common reported undesirable effects associated with Keppra® in combination with other AEDs was fatigue. Keppra® is also indicated for intravenous administration and is available as 100 mg/mL concentrate for solution for infusion. Undesirable effects that resulted from Keppra® intravenous use are similar to those associated with Keppra® oral use. Please consult local prescribing information.

About UCB Headquartered in Brussels (Belgium), UCB (www.ucb-group.com) is a leading global biopharmaceutical company dedicated to the research, development and commercialisation of innovative pharmaceutical and biotechnology products in the fields of central nervous system disorders, allergy/respiratory diseases, immune and inflammatory disorders and oncology - UCB focuses on securing a leading position in severe disease categories. Employing more than 8400 people in over 40 countries, UCB achieved revenue of 2.5 billion euro in 2006. UCB is listed on the Euronext Brussels Exchange and owns 87.6% of Schwarz Pharma.

For further enquiries, please contact

Jean-Christophe Donck Mareike Mohr Vice President, Associate Director, Investor Relations Corporate Communications and Investor Relations Tel. +32 2 559 9346 Tel. +32 2 559 9264

References [1] UCB Data on File [2] Neurological Disorders: Public Health Challenges. WHO Report 19
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