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UCB Announces Positive Top-Line Phase III Results for Keppra as,Adjunctive Therapy for Partial Onset Seizures in Paediatric,Patients from One Month to Less than Four Years of Age

partial onset seizures, the most common adverse events associated with Keppra® in combination with other antiepileptic drugs (AEDs) were somnolence, accidental injury, hostility, nervousness and asthenia. In patients 12 years of age and older with juvenile myoclonic epilepsy, the most common adverse events associated with Keppra® in combination with other AEDs were somnolence, neck pain and pharyngitis. In patients 6 years of age and older with idiopathic generalized epilepsy experiencing primary generalized tonic-clonic seizures, the most common adverse event associated with Keppra® in combination with other AEDs was nasopharyngitis. Keppra® is also available as an intravenous formulation for the adjunctive treatment of partial-onset seizures in adults with epilepsy. Keppra® injection is an alternative for patients when oral administration is temporarily not feasible. The adverse events that may result from Keppra® injection use for partial onset seizures include all those associated with Keppra® tablets and oral solution. For the U.S., prescribing information is available at www.keppra.com.

About Keppra® in Europe[5] Keppra® is indicated as monotherapy in the treatment of partial onset seizures with or without secondary generalisation in patients from 16 years of age with newly diagnosed epilepsy; as adjunctive therapy in the treatment of partial onset seizures with or without secondary generalisation in adults and children from 4 years of age with epilepsy; as adjunctive therapy in the treatment of myoclonic seizures in adults and adolescents from 12 years of age with JME and as adjunctive therapy in the treatment of PGTC seizures in adults and adolescents from 12 years of age with IGE. In monotherapy the most commonly reported undesirable effects were fatigue and somnolence. As adjunctive therapy in adults with partial onset seizures the most commonly reported undes
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