Navigation Links
Two New Imaging Studies Show Higher Dose Lipitor Stopped the,Progression of Atherosclerosis

mpared to Lipitor alone on the progression of atherosclerosis as measured by coronary intravascular ultrasound (IVUS) or carotid B-Mode ultrasound. IVUS is a relatively new, three-dimensional method of imaging to measure the total plaque volume in a cross-section of the coronary artery wall over the length of the vessel. Carotid ultrasound measures the thickness between the inner and middle layers of the carotid artery wall (IMT). All three trials had a run-in phase in which all patients were treated with Lipitor and patients' doses were titrated until individual LDL-C goals were reached. Patients were then randomized to either a combination of torcetrapib and Lipitor or Lipitor alone. Patients remained on the same dose of Lipitor for the duration of the two year study.

ILLUSTRATE

In patients with coronary heart disease randomized to Lipitor, progression of atherosclerosis was halted. Patients took an average dose of 23 mg of Lipitor (n=446). There was no significant change from baseline in percent atheroma volume (0.19%) and there was a significant regression of plaque build-up in the most diseased segment of the coronary artery (-3.3mm3).

RADIANCE 1

In patients with a genetic condition known as familial hypercholesterolemia resulting in extremely high LDL levels randomized to Lipitor, progression of atherosclerosis was halted. Patients took an average dose of 56 mg of Lipitor (n=427). There was no significant change from baseline in the IMT of the 12 carotid segments (0.0053mm/yr) nor in the common carotid artery (-0.0014mm/yr).

RADIANCE 2

Patients with high LDL and high triglycerides randomized to Lipitor experienced a progression of atherosclerosis. Patients took an average low, 13 mg dose of Lipitor (n=344). There was a significant change from baseline in the IMT of the 12 carotid segments (0.0296mm/yr) and a small but statistically significant change in the common carotid artery (0.0076mm/yr).

About the Overall
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Molecular Insight Pharmaceuticals, Inc. Presents Preclinical Data on Molecular Imaging Pharmaceutical for Prostate Cancer
2. Repligen Reports Positive Phase 2 Clinical Trial Results of Secretin for MRI Imaging of the Pancreas
3. Avid Announces Results of AV-1 Molecular Imaging Agent for Alzheimers Disease Presented at AD/PD Meeting
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
6. Studies of Drug Resistance May Lead to Individual Therapy for Rare Cancers
7. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
8. Insmed Inc. Welcomes Studies Linking IGFBP-3 to Prevention of Blindness in Premature Infants
9. Resveratrol Studies Suggest Broad Implications for SIRT1 Activation in Neurodegenerative Diseases of Aging Such as Alzheimers Disease
10. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
11. Phosphagenics Announces Positive Proof of Concept Results from Studies Utilizing Companys Dermal Drug Delivery Technology
Post Your Comments:
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "Global Peptide Cancer Therapeutics Market & Pipeline ... The conventional methods developed to prevent and eradicate ... cancer treatment. These methods are confined to low specificity, ... the researchers to look for a better solution. It ...
(Date:8/29/2014)... August 29, 2014 According ... Market by Extraction type (SFE, Cold Pressed, Organic ... Care, Pharmaceutical, Food Supplements, Fragrance, & Others) - Global ... defines and segments the Amaranth Seed Oil Market ... size in terms of value. The Amaranth Seed ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Research and Development Trend Forecast of Pharmaceutical Equipment ... Research and Development Trend Forecast of ... 2014-2018 mainly analyzes China,s pharmaceutical ... supply & demand, competition landscape, and business performance of ...
Breaking Medicine Technology:Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2
... In today,s payer-driven market, managed care formulary access is ... isn,t an end unto itself. In addition to formulary ... to effective pull-through programs and processes to increase market ... help organizations create and maintain effective pull-through programs and ...
... BEIJING, Nov. 12, 2010 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems ... "Company"), an emerging leader in the development, assembly, marketing ... in China, today announced its financial results for the ... revenues of $5.5 million and quarterly GAAP net income ...
Cached Medicine Technology:Creating a Platform for Managed Care Pull-Through Success in 2011 2Dehaier Medical Announces Third Quarter 2010 Financial Results 2Dehaier Medical Announces Third Quarter 2010 Financial Results 3Dehaier Medical Announces Third Quarter 2010 Financial Results 4Dehaier Medical Announces Third Quarter 2010 Financial Results 5Dehaier Medical Announces Third Quarter 2010 Financial Results 6Dehaier Medical Announces Third Quarter 2010 Financial Results 7Dehaier Medical Announces Third Quarter 2010 Financial Results 8Dehaier Medical Announces Third Quarter 2010 Financial Results 9
(Date:8/31/2014)... Memphis, TN (PRWEB) August 31, 2014 ... for ambulance safes and narcotics lockers ... to offer the MedixSafe brand for distribution worldwide. “We ... United Arab Emirates.” Lindsay McCollum, MedixSafe Sales Manager , ... Memphis based, electronic security and network cabling company with ...
(Date:8/31/2014)... 01, 2014 Recently, BambooIndustry.com, one of the ... with a new selection of bamboo veneers . Additionally, ... percent off) for these high quality products. The promotion will ... senior spokesman says that its top quality veneers are hot ... the new designs of bamboo veneers. All these items are ...
(Date:8/31/2014)... With years of hard work, Delta has now become ... Recently, the company has updated its wheel loader ... All these items are guaranteed to be great. Additionally, they ... It is true that all items in Delta’s used ... specialists. The firm is making full efforts to help worldwide ...
(Date:8/31/2014)... August 31, 2014 Asked to ... difference between "Bioavailability" and "absorption," Dr. Priya Khan, ... with great interest. "Bioavailability" and "absorption" are ... in the supplement industry, second perhaps only to ... Bioavailability and absorption, while related, are not the ...
(Date:8/31/2014)... (PRWEB) August 31, 2014 Ticket Down ... Bolivia tickets at Dick’s Sporting Goods Park in suburban ... a plethora of games against other international teams on USA ... Cup, Mexico brought a new soccer coach aboard, Miguel Herrera, ... In the build-up before the World Cup in Brazil, the ...
Breaking Medicine News(10 mins):Health News:Memphis-based Electronic Security Specialists Now Offers MedixSafe Narcotics Cabinets Internationally 2Health News:Memphis-based Electronic Security Specialists Now Offers MedixSafe Narcotics Cabinets Internationally 3Health News:High Quality Bamboo Veneers from Bambooindustry.com Receive International Attention 2Health News:Delta Updates Its Wheel Loader Assortment With A Lot Of Cheap Used Cat 966 Loaders 2Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 2Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 3Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 4Health News:Mexico vs. Bolivia Tickets at Dick’s Sporting Goods Park in Commerce City (Denver), CO: Ticket Down Slashes Ticket Prices on Mexico vs. Bolivia Exhibition Game 2Health News:Mexico vs. Bolivia Tickets at Dick’s Sporting Goods Park in Commerce City (Denver), CO: Ticket Down Slashes Ticket Prices on Mexico vs. Bolivia Exhibition Game 3
... process carbohydrates more slowly, expert says , MONDAY, April 12 ... quickly transformed into sugar in the blood raises the risk ... , The same effect, however, is not seen in men, ... Archives of Internal Medicine . , The study, by researchers ...
... April 12, 2010 A strategic alliance announced ... Limited will significant advance personalized medicine. The partnership ... companies to more rationally design and tailor their drugs ... variations that define a given disease. TD2 will ...
... lower esophagus develops almost exclusively in patients with ... reflux that affects approximately 3 million Americans. Although ... is poor, the chances of successful treatment increase ... early dysplastic stage. Now, a new endoscopic ...
... gynecologic surgery to address noncancerous symptoms said in a recently ... of the procedure on their sex lives. However, a ... express concern in this study that they might have less ... does not affect hormone levels. Among those in the ...
... tougher to get colonoscopies, study finds , MONDAY, April 12 ... are harder to find in areas of the United States ... could help explain why Hispanics are less likely to get ... group led by Dr. Jennifer Haas of Brigham and Women,s ...
... 10,000 women with early breast cancer has found wide variations ... practice, according to the May issue of the British ... Japan and America compared 9,779 women with an average age ... Greece, Japan, the Netherlands, the UK/Ireland and the USA. ...
Cached Medicine News:Health News:Simple Carbs Pose Heart Risk for Women 2Health News:Simple Carbs Pose Heart Risk for Women 3Health News:TGen Drug Development partners with Horizon Discovery for integrated personalized medicine service 2Health News:New form of endoscopic scanning improves detection of precancerous condition 2Health News:New form of endoscopic scanning improves detection of precancerous condition 3Health News:Most women facing gynecologic surgery don't worry about its effects on sex 2Health News:Most women facing gynecologic surgery don't worry about its effects on sex 3Health News:Most women facing gynecologic surgery don't worry about its effects on sex 4Health News:9-country study shows wide variations in how women with early breast cancer are treated 2
Stylish, comfortable and attractive, the new Keeler Sport frame is available in a choice of bright colors. The Keeler Sport frame can be worn over your own glasses, or your prescription can be incorp...
... the finest operating room stool available today. This ... surgeon who must remain absolutely steady for long ... shift resulting in unanticipated hand motion. The Machemer ... casters. A "foot bar" allows the surgeon to ...
This is a 2.5x focusing Galilean telescope with a range from 70cm to infinity. Ideal for use at sporting events, as well as for a wide range of hobbies....
This 6x or 8x aspheric magnifier is fitted with a distance piece and is particularly useful for patients with tremor or focusing difficulties. The magnifier can be either spectacle mounted or hand h...
Medicine Products: