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Trexima (Sumatriptan/Naproxen Sodium) Demonstrated Efficacy Across,Multiple Migraine Attacks

the remaining attack with placebo; the remaining patients treated all four attacks with Trexima.

In both studies, Trexima produced a consistent response from attack to attack experienced by individual study participants. In patients treating three attacks with Trexima, more than half of patients taking Trexima were pain free at two hours, more than three-quarters were pain-free at four hours, and about one-third achieved a sustained pain free response in at least two attacks; 29 percent were pain-free at two hours in all three attacks. Similar findings were reported among patients who treated all four attacks with Trexima.

As further evidence of the consistent response with Trexima, of patients who were pain free at two and four hours during the first attack, more than seven in 10 were pain-free in the second attack.

In more than 1,100 patients treating more than 3,300 attacks, adverse events reported in at least 2 percent of patients within 72 hours of taking Trexima were nausea, dizziness, dry mouth, somnolence and fatigue.

About Imitrex(R) (sumatriptan succinate) Tablets

Imitrex is a prescription medication indicated for the acute treatment of migraine in adults. Imitrex should only be used when a clear diagnosis of migraine has been established. Patients should not take Imitrex if they have certain types of heart disease, history of stroke or TIAs, peripheral vascular disease, Raynaud syndrome, or blood pressure that is uncontrolled. Patients with risk factors for heart disease, such as high blood pressure, high cholesterol, diabetes, or smoking, should be evaluated by a doctor before taking Imitrex. Very rarely, certain people, even some without heart disease, have had serious heart related problems. Patients who are pregnant, nursing, or taking medications should talk to their doctor.

About Naproxen Sodium

Naproxen sodium is a non-steroidal anti-inflammatory drug (NSAID) and is contained in Anaprox(R), Anaprox
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