Navigation Links
Topline Results of Phase III Study in Acute Ischemic Stroke,(Dias-2) Do Not Demonstrate Difference Between Desmoteplase and,Placebo

onders. Patients defined as responders by such criteria are in general able to function independently, having no or few deficits.

Improvement of clinical outcome was found with 47.4% of patients treated with 90 mcg/kg Desmoteplase and 36.4% of patients treated with 125 mcg/kg Desmoteplase, compared to 46.0% in the placebo group with neither dose of Desmoteplase statistically significantly different compared to placebo.

The rate of symptomatic intracranial bleeding within 72 hours after study drug administration was 0% in the placebo group, 3.5% in the 90 mcg/kg dose group and 4.5% in the 125 mcg/kg group. There were four patient deaths reported in the placebo group, three reported in the 90 mcg/kg dose group and 14 reported in the 125 mcg/kg dose group within the 90 day follow-up period. Ten of the 14 deaths in the 125 mcg/kg dose group were considered by the investigators as not related to the drug, 9 of which occurred 14 or more days after stroke and were from non-neurological causes.

These data are surprising and are not consistent with previously observed patterns in the DIAS/DEDAS trials and larger size, placebo-controlled acute stroke trials. The absence of consistency with previous findings is not easy to explain, but in-depth analyses are planned to better understand the data.

Forest will review the complete study database over the coming weeks to determine the appropriate next steps and its role regarding U.S. development of desmoteplase.

The headline results of the DIAS-2 study will be presented on 1 June 2007 at 10:45 a.m. BST within the "Large Clinical Trials II" session at the XVI European Stroke Conference in Glasgow, Scotland, U.K.

PAION will host a conference call on 1 June 2007 to discuss the DIAS-2 headline results starting at 1:00 p.m. BST (02:00 p.m. CEST, 08:00 a.m. EDT). To access the call please dial +44 20 7138 0819 UK, +49 69 9897 2634 Germany, +1 718 354 1361 USA. Title: "PAION DIAS-2 results"

<
'"/>




Page: 1 2 3 4

Related medicine technology :

1. deCODE Announces Positive Topline Results for Phase I Study of DG051 for the Prevention of Heart Attack
2. CombinatoRx Provides Topline Results from Phase 2 RA Study with CRx-139 and Very Low Dose Prednisolone
3. CV Therapeutics Announces Topline MERLIN TIMI-36 Results
4. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
5. Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
6. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
7. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
8. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
9. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
10. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
11. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
Post Your Comments:
(Date:10/19/2014)... 2014 CTI BioPharma Corp. (CTI) (NASDAQ and ... third quarter 2014 financial results on Wednesday, October 29, ... Following the announcement, members of the management team will ... and provide a general corporate update at 4:30 p.m. ... be obtained as follows: Wednesday, October 29 ...
(Date:10/17/2014)... Oct. 17, 2014  Training market researchers to ... success factor in today,s highly competitive global marketplace. ... organizations that effectively and efficiently produce high performing ... area. Effective training programs can ... recognition from internal clients by developing analysts who ...
(Date:10/17/2014)... DUBLIN , Oct. 17, 2014 ... of the "Research and Development Prospect of ... offering. Based on the 2013 ... Chinese government policies about dialysis industry and the ... in-depth research about dialysis industry segmentations. Moreover, it ...
Breaking Medicine Technology:CTI BioPharma to Report Third Quarter 2014 Financial Results on October 29, 2014 2Effective Training Programs for Market Research Groups can Boost Overall Organizational Success 2Research and Development Prospect of China Dialysis Market, 2014-2018 2Research and Development Prospect of China Dialysis Market, 2014-2018 3
... /PRNewswire-Asia/ -- Global Pharm Holdings Group, Inc. ... a China-based, growing vertically integrated pharmaceutical company ... Medicine ("TCM") herbs cultivation and processing business ... and Shandong provinces, today announced that it ...
... Oct. 26, 2011 AtheroNova Inc. (OTCBB: AHRO), a ... compounds to regress atherosclerotic plaque, today announced that it ... the U.S. Food and Drug Administration (FDA). During the ... of AHRO-001, AtheroNova,s lead patent-pending compound for the prevention ...
Cached Medicine Technology:Global Pharm Announces the Closing of US$15 Million Redeemable Convertible Bonds Financing 2Global Pharm Announces the Closing of US$15 Million Redeemable Convertible Bonds Financing 3AtheroNova Completes Successful Pre-IND Meeting with FDA on AHRO-001 2AtheroNova Completes Successful Pre-IND Meeting with FDA on AHRO-001 3
(Date:10/19/2014)... Recently, BambooIndustry.com, one of the most popular suppliers of ... bamboo deckings . Moreover, the company has launched a ... available at deeply discounted rates. , As is ... the significance of online business nowadays. Thus, BambooIndustry.com pays ... workers are striving to deliver both value and efficiency ...
(Date:10/19/2014)... 2014 This report provides comprehensive ... complete with comparative analysis at various stages, therapeutics ... route of administration (RoA) and molecule type, along ... releases. It also reviews key players involved in ... features on late-stage and discontinued projects. , Partial ...
(Date:10/19/2014)... 20, 2014 Recently, Top10BestSEOHosting.com has ... that JustHost, GoDaddy and HostMonster are the best ... (Virtual Private Server) is the method of partitioning ... of which has the appearance and capabilities of ... why the site pays close attention to VPS ...
(Date:10/19/2014)... SweetDressy.com, a professional company of women’s dresses and ... evening dresses . All the company’s old and ... discount is up to 66 percent off. , ... fashion field. Its dress specialists are striving to make ... of the world. All the company’s items are unique, ...
(Date:10/19/2014)... Stephen T. Greenberg, M.D., with offices in Woodbury, Southampton and ... as one of Long Island’s best cosmetic surgeons. In ... the best provider for Botox injections. Glisten, his Skin & ... best Laser Treatment center on Long Island.* , The voting ... the contest once per day, per IP address. , Stephen ...
Breaking Medicine News(10 mins):Health News:High Quality Bamboo Deckings, New Items Unveiled By BambooIndustry.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 4Health News:The Best VPS Hosting Suppliers In The Market Unveiled By Top10BestSEOHosting.com 2Health News:Promotion For Beautiful Long Evening Dresses Launched By SweetDressy.com 2Health News:Dr. Stephen T. Greenberg – Nominated for the 10th Consecutive Year for One of Long Island’s Best Cosmetic Surgeons for 2015 by the Long Island Press 2
... for Pyratine-6(TM) and Pyratine XR(TM)NAPA, Calif., March 31 ... company engaged in the development of technologies that target ... fourth quarter and year ended December 31, 2008. Revenue ... compared with $26,471,000 reported in 2007. Revenues for ...
... DST Systems, Inc. (NYSE: DST ) has ... Systems, Inc. ("Argus"). Argus is now a wholly-owned subsidiary of ... may include forward-looking statements respecting DST and its businesses. Such ... today, and actual actions or results could differ. There could ...
... MSC Care Management, the industry,s ... post-discharge and post-injury workers, compensation claimants nationwide, announced ... Transportation, a national company also focused on the ... position in the market, providing specialized workers, compensation ...
... researchers and private sector biotech scientists will collaborate ... project to discover blood markers that could identify people ... been launched by the Framingham Heart Study. , Researchers ... to Biomarker Research in Cardiovascular Disease, will analyze about ...
... rates to those with the worst marks , , TUESDAY, March ... patients trying to figure out which hospital will provide the ... hospital safety rating conducted by the Leapfrog Group, a nonprofit ... on the safety survey had about the same rate of ...
... Minneapolis-based Courage Center, a nonprofit rehabilitation and resource center, ... , The 2009 Jay ... Center to people with disabilities who have achieved outstanding vocational ... this employment award and receive a $2,000 cash award. , ...
Cached Medicine News:Health News:Senetek PLC Reports 2008 Financial Results 2Health News:Senetek PLC Reports 2008 Financial Results 3Health News:MSC Acquires Optimal Translation & Transportation 2Health News:Effort Could Lead to Blood Tests for Heart Problems 2Health News:Study Casts Doubt on Influential Hospital Safety Survey 2Health News:Study Casts Doubt on Influential Hospital Safety Survey 3Health News:Courage Center Now Accepting Nominations for Jay and Rose Phillips Awards and Phillips Caregiver Award 2
A distal femoral nail providing high purchase in osteoporotic metaphyseal bone and two distal locking options: one spiral blade plus one locking screw or two locking screws....
... to information on the Internet is finally ... enabling you to interact with your PC ... Voice Information Retrieval Software, you can ask ... topics and receive up-to-date information from the ...
... non-invasive and painless method of stimulating the ... manufactures two magnetic stimulation devices, the MES-10 ... The Hight Speed MES-10 magnetic ... to 25 Hz at full power. ...
... monitor ever made, with all the capabilities you'll ... weight and a third the size of any ... everything you need for cardiac resuscitation: fast, easy ... monitoring, built-in AC or DC power, and an ...
Medicine Products: