Navigation Links
Theratechnologies: TH9507 Phase 3 Clinical Update

- Data from first Phase 3 trial presented at ENDO 2007

- Regulatory approvals for second Phase 3 trial open the door for patient recruitment in Europe

MONTREAL, QUEBEC -- (MARKET WIRE) -- June 04, 2007 -- Theratechnologies (TSX: TH) reported today that 26-week data from its first Phase 3 study testing TH9507 in HIV-associated lipodystrophy were presented today in Toronto at ENDO, the 89th annual meeting of the Endocrine Society. The presentation was made by Dr. Steve Grinspoon, Associate Professor of Medicine, Harvard Medical School and lead investigator for the TH9507 trial in the United States.

Positive 26-week results were recently presented at the 14th Conference on Retroviruses and Opportunistic Infections (CROI). The primary endpoint and important secondary endpoints were achieved. The study was powered to detect an 8% reduction in visceral adipose tissue (VAT) versus placebo. After 26 weeks, patients on TH9507 achieved a 15% reduction in VAT versus baseline and a 20% difference versus placebo. In general, TH9507 was shown to be well tolerated by patients.

Dr. Grinspoon´s presentation today particularly highlighted beneficial effects of TH9507 on key metabolic parameters known to be risk factors for cardiovascular diseases, suggesting that strategies using a growth hormone releasing factor will reduce abdominal obesity and may lower cardiovascular risk in HIV patients.

Since the initiation of the trial in January, Theratechnologies has obtained regulatory approval in five European countries for its second Phase 3 clinical study testing TH9507 in HIV-associated lipodystrophy. Patients are being enrolled for the study in Belgium, France, Italy, Spain and the United Kingdom. North American recruitment previously began in the United States in January and Canadian recruitment began in May.

The second Phase 3 trial is a 400-patient, multi-center, double-blind, randomized, placebo-con
'"/>




Page: 1 2 3

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
7. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
8. NexMed Announces Completion of Patient Enrollment in Two Pivotal Phase 3 Studies for Anti-Fungal Product
9. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Theratechnologies Phase Clinical Update
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) announces ... condition to the announced tender offer for all of the outstanding ... result of the waiver, the transaction is no longer conditional on ... January 24, 2014 following the currently scheduled expiration time, subject to ...
(Date:1/15/2014)... BEACH GARDENS, Fla. , Jan. 15, 2014  In an unprecedented ... difficile and TB in ambulances and other transport vehicles, an advanced ... used by rescue personnel for the first time. ... in contact with these deadly pathogens, West Palm Beach ...
(Date:1/15/2014)... Jan. 15, 2014 The Cadence Fitness & Health ... by the Medical Fitness Association, a non-profit organization assisting ... full potential. The Cadence Fitness & Health Center is ... and second in the Chicagoland area. "The ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... Guard Against,Hospital Infections, KANSAS CITY, Kan., April 02, ... ten leading causes of death in the,United States, ... countless stories about patients who go into hospitals ... As a,patient, knowing the right questions to ask ...
... 2007--Rapamycin, an FDA-approved drug,normally used to help prevent ... and also used to coat cardiac stents, was,highly ... in mice. In a study published in the ... at the National,Cancer Institute (NCI), part of the ...
Cached Medicine Technology:Six Important Things to Know About Preventing Hospital Infections 2Six Important Things to Know About Preventing Hospital Infections 3Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice 2Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice 3Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice 4
(Date:4/17/2014)... One of the most popular vaccine brands for children ... may be overlooking some cost factors when choosing vaccines, ... expensive option, according to a new study by University ... administer can be driven by numerous factors," says Sheldon ... professor of computer science and of mathematics at the ...
(Date:4/17/2014)... a review published in the April issue of ... Feinstein Institute for Medical Research, says it,s time to ... approach to treating sepsis, which kills millions worldwide ... occurs when molecules released into the bloodstream to fight ... Inflammation is necessary for maintaining good health without ...
(Date:4/17/2014)... It,s estimated that as many as 10 million older ... of loneliness and isolation. , However, new research ... retired older Americans for six years found that ... of depression by more than 30 percent. , "That,s ... State University professor of telecommunication, information studies and media ...
(Date:4/17/2014)... YORK April 17, 2014 EcoHealth Alliance, a ... health issues, published a comprehensive review today examining the ... Marburg virus. The review calls for improved global surveillance ... as the recent outbreak of Ebola in West Africa ... the countries of Guinea and Liberia. According to ...
(Date:4/17/2014)... uncommon these days to find a colored ribbon representing a ... cancer. But what color ribbon does one think of with ... color, for many suffering from the disease, black may be ... study consisting of lung cancer patients, primarily smokers between the ... light on the stigma often felt by these patients, the ...
Breaking Medicine News(10 mins):Health News:Study recalculates costs of combination vaccines 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Internet use can help ward off depression among elderly 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:Unraveling the 'black ribbon' around lung cancer 2
... Women experiencing physical abuse from intimate partners spent 42 percent ... to a long-term study of more than 3,000 women. , ... study revealed that women who suffered physical abuse five or ... on health care than women who were never abused. , ...
... Gray of Chicago, IL, will travel to Washington, D.C., ... meet with congressional leaders and gain their support for ... cure for epilepsy.Gray, 9, is one of 37 young ... Speak Up! , a national program coordinated by the ...
... the European UnionEAST PROVIDENCE, R.I., March 23 ... the innovative IlluminOss(TM) Photodynamic Bone Stabilization System for ... granted a CE Mark. The approval permits ... European Union (EU).IlluminOss Medical is beginning the process ...
... Healthcare ProfessionalsVOORHEES, N.J., March 23 The epidemiology ... changing rapidly and has been marked by a ... CDI can be challenging and guidelines for treatment ... effectively implement key strategies for reducing the incidence ...
... African Health Conference in Kenya SILVER SPRING, Md., ... a communications, research, and technology firm, will share the ... mobile video-enabled phones in meeting the requirements for monitoring ... East African Health and Scientific Conference. The findings ...
... MALVERN, Pa., March 23 Fujirebio Diagnostics, Inc., ... leader in cancer biomarker assays, today announced the ... Officer. Dr. Barnes comes to Fujirebio Diagnostics ... has held various positions at Abbott and Meridian ...
Cached Medicine News:Health News:Physical abuse raises women's health costs over 40 percent 2Health News:Illinois Youth Shares Epilepsy Message on Capitol Hill 2Health News:IlluminOss(TM) Photodynamic Bone Stabilization System Receives CE Mark 2Health News:Clostridium difficile Infection in Primary Care: Tackling a Virulent Pathogen 2Health News:Pilot Study Using Video Cell Phones for Mobile Direct Observation Treatment (MDOT) to Monitor Medication Compliance of TB Patients 2Health News:Pilot Study Using Video Cell Phones for Mobile Direct Observation Treatment (MDOT) to Monitor Medication Compliance of TB Patients 3Health News:Pilot Study Using Video Cell Phones for Mobile Direct Observation Treatment (MDOT) to Monitor Medication Compliance of TB Patients 4Health News:Fujirebio Diagnostics Appoints Grady Barnes as Chief Scientific Officer 2
... Protection Made Easy. The new generation FilterWire ... and ease of use, providing you with ... stenting and angioplasty procedures., ,The FilterWire EZ ... requiring minimal changes to technique. The ...
... sizes, noise is not a factor with ... For use with mini-crocodile clip lead wires ... x 2.5 cm (.875 x 1 in), ... 100-count package contains 10 individually sealed sets ...
... and patient information from all cardiology ... one central system. It simplifies the ... so that healthcare professionals can focus ... people., ,Many Sources, One Solution ,Multi-modality ...
... Xi300 is so bright many surgeons turn it ... to shift into when the going gets tough. ... a true Hot Start and the technologically advanced ... that prevent failed start ups and overheating. The ...
Medicine Products: