Navigation Links
Targeted Genetics Reports Inflammatory Arthritis Clinical Data at,European Rheumatology Conference

BARCELONA, SPAIN and SEATTLE, WA -- (MARKET WIRE) -- June 14, 2007 -- Targeted Genetics Corporation (NASDAQ: TGEN) today is reporting data from the dose escalation arm of the ongoing Phase I/II clinical study of tgAAC94 in patients with inflammatory arthritis. Philip J. Mease, M.D., clinical professor at the University of Washington School of Medicine, chief of rheumatology clinical research at the Swedish Medical Center, practicing physician with Seattle Rheumatology Associates and the lead investigator on the trial is presenting the data in a poster session today at the Annual European Congress of Rheumatology EULAR 2007 in Barcelona, Spain (Abstract THU0185). These data also were reported earlier this month at the 10th Annual Meeting of the American Society of Gene Therapy.

Interim aggregate data on the primary and secondary end-points were presented from the first 61 subjects in the dose escalation portion (cohorts 1 to 3) of the Phase I/II clinical trial of tgAAC94 in patients with inflammatory arthritis. Completion of enrollment and initial dosing of all subjects in the second segment (cohorts 4 to 6) of this trial was announced recently. tgAAC94 is an investigational therapeutic designed to inhibit the activity of tumor necrosis factor-alpha (TNF-alpha), a key mediator of inflammation. The Phase I/II study is designed to assess the safety and potential effect of different doses of tgAAC94 administered directly to affected joints of subjects with inflammatory arthritis with or without concurrent use of systemic TNF antagonist therapies.

"Despite progress in recent years in treating inflammatory arthritis, many patients have disease that remains refractory to current therapy including systemic TNF antagonists," said Dr. Mease. "These data suggest that tgAAC94 may provide clinical benefit to these patients, even in those who are being treated with TNF antagonists. Confirmation of these data in
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
2. Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
3. Antisense Pharma: Promising Phase IIb Results of Targeted Therapy with AP 12009 in Recurrent Anaplastic Astrocytoma
4. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
5. ApoCells Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
6. News from the Battlefield of Metastatic Cancer: Epeius Biotechnologies Draws the Sword of Targeted Gene Delivery (Rexin-G) from the Stone of Chemistry and Physics
7. Data Show SuperGens Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51
8. Calando Pharmaceuticals Announces Preclinical Efficacy and Safety Data of Targeted, Systemic Delivery of siRNA at AACR Annual Meeting
9. Arrowhead Subsidiary, Calando Pharmaceuticals Publishes Study on Targeted, Systemic Delivery of siRNA
10. Calando Pharmaceuticals Publishes the First Non-Human Primate Study on Targeted, Systemic Delivery of siRNA in National Academy of Sciences Journal
11. Data From Adherexs European Phase Ib/II Trial of ADH-1 to be Presented at International Symposium on Targeted Anticancer Therapies
Post Your Comments:
(Date:2/27/2015)... TORONTO , Feb. 27, 2015  Bionik Laboratories ... (the "Company"), announced today that it acquired Bionik Laboratories, ... Laboratories"), and completed the sale to qualified accredited investors ... for aggregate gross proceeds of approximately $6.2 million. Shares ... quoted on the OTC Markets under the symbol "DWTPD" ...
(Date:2/26/2015)... -- Finesse expands office in Leicester, United Kingdom ... of its operations in Leicester , ... for customers is expected shortly afterward. With ... the current office, the new premises will double the ... Finesse to bring on more service personnel. The new ...
(Date:2/26/2015)... 26, 2015  AbbVie (NYSE: ABBV ... in its neuroscience and oncology development programs have ... American Academy of Neurology annual meeting in ... 18-25. The accepted abstracts feature results from studies ... investigational treatments in AbbVie,s pipeline. Presentations will include ...
Breaking Medicine Technology:Bionik Laboratories Raises $6.2 Million 2Bionik Laboratories Raises $6.2 Million 3New Finesse Office in United Kingdom 2AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 2AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 3AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 4AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 5AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 6AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 7
(Date:2/28/2015)... 28, 2015 March—also known as ... to remind ourselves and others that suspected head ... NeuroSurgical Specialists (ANS). , Concussions are a form ... 75% of TBIs. There are 1.6-3.8 million sports-related ... benign, but it is a brain injury. Many ...
(Date:2/28/2015)... Vancouver personal injury lawyers at Jiwa Law Corporation recently announced ... They stated that in many cases, missing an important time ... Many a time, delays in making an injury claim can ... As a result, experts at Jiwa Law Corporation suggest that ... injury lawyer in order to know more about their rights. ...
(Date:2/28/2015)... A study out of the University of Oxford ... the treatment of a hereditary ocular condition that leads ... Dr. Robert MacLaren, professor of ophthalmology at the University ... on January 16, 2014 , the study treated six ... mostly affects men and leads to the degeneration of ...
(Date:2/28/2015)... 28, 2015 The Mesothelioma Applied ... awards at the International Symposium on Malignant Mesothelioma on ... at the Hyatt Regency Bethesda in Bethesda, Maryland. The ... work and commitment to the mission to cure mesothelioma. ... will be presented to Miriam Ratner. Miriam runs the ...
(Date:2/28/2015)... February 28, 2015 National ... outsourced sales, marketing and supply chain management for ... Botanicals, is bringing its award winning solutions for ... Botanicals’ products are specifically created to combat thinning-damaged ... BIOTA is committed to marrying science with nature ...
Breaking Medicine News(10 mins):Health News:Atlantic NeuroSurgical Specialists (ANS) Focus on National Brain Injury Awareness Month to Educate the General Public on Head Trauma 2Health News:Atlantic NeuroSurgical Specialists (ANS) Focus on National Brain Injury Awareness Month to Educate the General Public on Head Trauma 3Health News:Jiwa Law Corporation Recently Announced That Time Delays May Weaken Personal Injury Claims 2Health News:New Gene Therapy Procedure Could Hold Key to Preventing Blindness for Certain Patients 2Health News:Cancer Research Foundation Honors Award Recipients 2Health News:Cancer Research Foundation Honors Award Recipients 3Health News:Cancer Research Foundation Honors Award Recipients 4Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 2Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 3
... sexually explicit, nude, or semi-nude photos by cell phone ... and teens. A new poll shows that the vast majority ... sext. Seventeen states have already enacted laws to address ... 2012 that focuses on sexting. The University ...
... 20 (HealthDay News) -- Seeing a baby,s face triggers a ... and planning movement, a finding researchers say may indicate a ... observed this pattern in adults who didn,t know the baby ... adults have no children of their own. Yet images of ...
... of scientific sessions will be devoted to the latest ... Heart Failure Congress 2012. The latest results from drugs ... Devices are one of the hottest topics in ... year,s main theme, "Treatment of heart failure: integrating pharmacology ...
... 20 (HealthDay News) -- The anti-inflammatory and painkiller ibuprofen ... to a new study. Headache, fatigue, nausea, dizziness, ... altitude sickness, which affects more than 25 percent of ... ski, hike or camp. If unrecognized or untreated, ...
... internal medicine physicians, or internists, subspecialists, medical students, and ... Internal Medicine 2012, the annual scientific meeting of the ... (Thursday - Saturday), at the Ernest N. Morial Convention ... of illnesses in adults. Internal Medicine 2012 is ...
... for early-career researchers in Germany have been announced. The ... Research Foundation) and the German Federal Ministry of Education ... three young women to receive the Heinz Maier-Leibnitz Prize ... Gebauer, Chemistry, University of Constance, Dr. Lisa Kaltenegger, Physics, ...
Cached Medicine News:Health News:For youth sexting: Public supports education, not criminal charges 2Health News:Infants' Faces Trigger Caregiving Impulse in Adults' Brains 2Health News:The world's largest heart failure congress -- Heart Failure Congress 2012 2Health News:The world's largest heart failure congress -- Heart Failure Congress 2012 3Health News:Ibuprofen May Ward Off Altitude Sickness 2Health News:From diabetes to disaster relief: Story opportunities at Internal Medicine 2012 in New Orleans 2Health News:DFG announces recipients of 2012 Heinz Maier-Leibnitz Prize 2Health News:DFG announces recipients of 2012 Heinz Maier-Leibnitz Prize 3Health News:DFG announces recipients of 2012 Heinz Maier-Leibnitz Prize 4Health News:DFG announces recipients of 2012 Heinz Maier-Leibnitz Prize 5
... Comfy™ Knee Orthosis ... non-fixed knee contractures. Goniometer ... joint. No exposed metal ... covers and laundry bag. ...
... is a support designed to treat patellofemoral ... the patella and compresses the surrounding area ... patella. During ambulation, the aircell also provides ... pain. A moveable aircell is included that ...
Swedish Knee Cage -- hinged to track knee motion. Effective control of genu recurvatum (back knee or knee hyperextension). Fits left or right....
... uses an aircell to focus ... helping to relieve symptoms of ... Focusing the pressure decreases stress ... less constriction of the poples. ...
Medicine Products: