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Targanta Reports Improved Ability of Oritavancin to Stop Bacteria,Growth In Vitro Compared With Other Glycopeptide Antibiotics

uding two large multi-national Phase 3 studies in complicated skin and skin structure infections performed by former developers Lilly and InterMune, Inc. Targanta expects to file a New Drug Application (NDA) for oritavancin with the U.S. Food and Drug Administration in the second half of 2007.

About Targanta Therapeutics

Targanta Therapeutics is a privately held biopharmaceutical company developing and commercializing antibacterial drugs to treat serious infections in the hospital setting. Its pipeline includes an array of antibacterial agents in various stages of development. The company has operations in Cambridge, MA, Indianapolis, IN, and Montreal, Canada. For further information about Targanta, visit the company website, http://www.targanta.com.

Disclaimer

All forward-looking statements and other information included in this press release are based on information available to Targanta as of the date hereof, and Targanta assumes no obligation to update any such forward-looking statements or information. Targanta's actual results could differ materially from those described in Targanta's forward-looking statements.

    (1) Centers for Disease Control and Prevention, Coordinating Center for

        Infectious Diseases / Division of Bacterial and Mycotic Diseases,

        http://www.cdc.gov/ncidod/dbmd/diseaseinfo/staphylococcus_food_g.htm


    (2) Centers for Disease Control and Prevention, Coordinating Center for

        Infectious Diseases / Division of Bacterial and Mycotic Diseases,

        http://www.cdc.gov/ncidod/dbmd/diseaseinfo/streppneum_t.htm


CONTACT: Gayle Crick Fischer, R.Ph. of Targanta Therapeutics,+1-317-502-2467; or Danette Berry of Spectrum Science C
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