Navigation Links
Survival Data Available From Erbitux Study in First-Line Treatment,of Advanced Head and Neck Cancer

nt due to adverse events. Two of these discontinuations were due to cardiac events (myocardial infarction in one patient and arrhythmia, diminished cardiac output, and hypotension in the other patient).

The incidence of hypomagnesemia (both overall and severe [NCI CTC Grades 3 & 4]) was increased in patients receiving ERBITUX alone or in combination with chemotherapy as compared to those receiving best supportive care or chemotherapy alone based on ongoing, controlled clinical trials in 244 patients. Approximately one-half of these patients receiving ERBITUX experienced hypomagnesemia and 10-15% experienced severe hypomagnesemia. Electrolyte repletion was necessary in some patients and in severe cases, intravenous replacement was required. Patients receiving ERBITUX therapy should be periodically monitored for hypomagnesemia, and accompanying hypocalcemia and hypokalemia during, and up to 8 weeks following the completion of, ERBITUX therapy.

The most serious adverse reactions associated with ERBITUX in combination with radiation therapy in 208 patients with head and neck cancer were infusion reaction (3%), cardiopulmonary arrest (2%), dermatologic toxicity (2.5%), mucositis (6%), radiation dermatitis (3%), confusion (2%), and diarrhea (2%).

The most serious adverse reactions associated with ERBITUX in mCRC clinical trials (N=774) were infusion reaction (3%), dermatologic toxicity (1%), interstitial lung disease (0.4%), fever (5%), sepsis (3%), kidney failure (2%), pulmonary embolus (1%), dehydration (5% in patients receiving ERBITUX with irinotecan, 2% in patients receiving ERBITUX as a single agent) and diarrhea (6% in patients receiving ERBITUX with irinotecan, 0.2% in patients receiving ERBITUX as a single agent).

The overall incidence of late radiation toxicities (any grade) was higher with ERBITUX in combination with radiation therapy compared with radiation therapy alone. The following sites were affected: salivary glands (65%/5
'"/>




Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival
2. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
3. The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients
4. Velcade (bortezomib) for Injection Based Therapies Achieved Survival Rates as High as 100 Percent in Newly Diagnosed Multiple Myeloma Patients
5. Velcade (bortezomib) for Injection Survival Data in Front-Line Multiple Myeloma Patients to be Featured at 11th International Myeloma Workshop
6. Research Documents Scalable Production, Survival Following Engraftment and Positive Impact on Cardiac Function in Infarcted Rats for Gerons Human Embryonic Stem Cell-Based Therapeutic for Heart Failure
7. Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal Women with Early Breast Cancer Receiving Treatment with Tamoxifen
8. Ivivis PEMF Technology Significantly Improves Neuron Survival in Parkinsons Disease Model, Study Finds
9. Synta Presents Results for STA-4783 in Metastatic Melanoma Showing Improvement in Overall Survival
10. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
11. Updated Study Results Reinforce Survival Benefit of Taxotere (Docetaxel) for Men with Advanced, Hormone-Resistant Prostate Cancer
Post Your Comments:
(Date:12/15/2009)... Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs ... and 1 abstention that AstraZeneca has established sufficient benefit ... of CRESTOR® (rosuvastatin calcium) in individuals meeting the following ... 50 years, women greater than or equal to 60 ... greater than or equal to 2.0 mg/L; Triglycerides <500 ...
(Date:12/15/2009)... Dec. 15 Medical researchers with EDP ... their revolutionary new technology for a simple blood ... ,, Following the success of its pre-clinical trials ... patent on the biomarker, CA11-19, and all aspects ... test, ColoMarker(TM) will detect colon cancer in its ...
(Date:12/15/2009)... 15 Certified healthcare providers who have ... from the H1N1 flu virus may now offer ... Department of Health announced today. ,, Pennsylvania ... because approximately 3.2 million doses of vaccine have ... to individuals in the priority groups. ,, "Many ...
Breaking Medicine Technology:Favorable Vote from FDA Advisory Committee on Benefit/Risk of CRESTOR(R) (rosuvastatin calcium) in JUPITER Study 2Favorable Vote from FDA Advisory Committee on Benefit/Risk of CRESTOR(R) (rosuvastatin calcium) in JUPITER Study 3Favorable Vote from FDA Advisory Committee on Benefit/Risk of CRESTOR(R) (rosuvastatin calcium) in JUPITER Study 4Favorable Vote from FDA Advisory Committee on Benefit/Risk of CRESTOR(R) (rosuvastatin calcium) in JUPITER Study 5Researchers Announce Medical Breakthrough with Simple, Inexpensive Blood Test for Colon Cancer 2Department of Health Urges Expanded H1N1 Vaccination Efforts to Include All Patients 2Parsippany Takes Top Honors in New Jerseys First Ever Toxic Waistlines Contest 51260 1Parsippany Takes Top Honors in New Jerseys First Ever Toxic Waistlines Contest 51260 2Parsippany Takes Top Honors in New Jerseys First Ever Toxic Waistlines Contest 51260 3For Kids Two Languages Can Be as Easy as One 51259 1For Kids Two Languages Can Be as Easy as One 51259 2For Kids Two Languages Can Be as Easy as One 51259 3The Path to Pregnancy 3A Fairhaven Health Offers New Natural Products to Help Couples Conceive 51257 1The Path to Pregnancy 3A Fairhaven Health Offers New Natural Products to Help Couples Conceive 51257 2The Path to Pregnancy 3A Fairhaven Health Offers New Natural Products to Help Couples Conceive 51257 3The Path to Pregnancy 3A Fairhaven Health Offers New Natural Products to Help Couples Conceive 51257 4The Path to Pregnancy 3A Fairhaven Health Offers New Natural Products to Help Couples Conceive 51257 5
(Date:12/15/2009)... swine flu were worse, ,we would have really been ... News) -- The outbreak of the pandemic H1N1 swine ... to respond to public health emergencies, a new report ... America,s Health and the Robert Wood Johnson Foundation, also ... public health system. , "The 2009 H1N1 outbreak is ...
(Date:12/15/2009)... Prostate cancer tests promised but not delivered ... Network calls on Congress to ensure that healthcare ... benefit currently required of insurance companies in 37 ... for those segments of the population and individuals ... American men and men who have a family ...
(Date:12/15/2009)... Dec. 15 4R Systems, Inc., a ... solutions which help retailers significantly increase profits by ... announced today that The Vitamin Shoppe has been ... "4R,s store and DC inventory solutions have helped ... and in-stocks over the last two years," said ...
(Date:12/15/2009)... YORK, Dec. 15 The following are the ... General for the criminal division, at the Medicare ... Secretary Sebelius. And thank you for the enormous ... HEAT initiative. ,, Together, our Departments have ... results. ,, We,ve made tremendous progress in fighting ...
(Date:12/15/2009)... Continuing Strike Force Operations Lead to Indictment of ... with more than $61 Million in Fraudulent Billing ... Thirty people have been charged in ... to submit more than $61 million in false ... of the Medicare Fraud Strike Force, Department of ...
Breaking Medicine News(10 mins):Health News:Serious Gaps Revealed in U.S. Response to Health Emergencies 2Health News:Serious Gaps Revealed in U.S. Response to Health Emergencies 3Health News:Men's Health Network Calls on Congress to Complete President Obama's Promise on Health Care Reform 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 3Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 4Health News:Remarks by Lanny A. Breuer, Assistant Attorney General for the Criminal Division, at the Medicare Fraud Strike Force Press Conference 2Health News:Remarks by Lanny A. Breuer, Assistant Attorney General for the Criminal Division, at the Medicare Fraud Strike Force Press Conference 3Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 2Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 3Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 4Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 5
... of Representatives, Extension of Medicare Secondary Payer (MSP),for ... and,Family Benefits for Patients, WASHINGTON, Oct. 22 ... Medicare Protection (CHAMP) Act of 2007,provision to extend ... Renal,Disease (ESRD) program for patients who rely on ...
... its impressive past,successes, the Midwest Orthopaedic Research Foundation ... propel it forward in the coming decade. This,vision, ... will solidify MORF as a world-class research institution ... will be restructuring the board of directors,and embarking ...
... Fund Expanded Health Care Access for Marylanders, ... for next week,s special session to resolve a ... Governor Martin,O,Malley,s proposed $1 cigarette tax increase would ... reduce tobacco-related health,care costs and save thousands of ...
... all the difference, report finds , , MONDAY, Oct. 22 ... saved by a coordinated global effort to improve nutrition ... fuels in underdeveloped countries, a new study finds. , ... of almost 1.5 million children in sub-Saharan Africa, 800,000 ...
... Breeze Ltd., the leader in,Vibration response imaging (VRI(TM)) ... will now be available in the US. The,VRIxp(TM) ... providers to,see and monitor lung sounds without exposing ... Company announced the phased U.S. launch at The,American ...
... U.S. donors increased their charitable contributions to health care,facilities ... to $7.9,billion was substantially lower than the 16 percent ... to a new "Report on Giving" issued today,by The ... being eroded and the health care system is,being stressed ...
Other Medicine News:Health News:Kidney Care Community Voices Strong Support for Kidney Patients' Right to Choose 2Health News:Kidney Care Community Voices Strong Support for Kidney Patients' Right to Choose 3Health News:New Report: Increasing Maryland's Cigarette Tax Will Reduce Smoking, Save Lives and Save Money 2Health News:Saving Millions of Children's Lives Is Possible 2Health News:Deep Breeze Ltd. Launches Unique Non-Invasive, Radiation-Free Pulmonary Imaging System in the U.S. 2Health News:Deep Breeze Ltd. Launches Unique Non-Invasive, Radiation-Free Pulmonary Imaging System in the U.S. 3Health News:Philanthropic Giving for Health Care Slows in 2006 in both U.S. and Canada, According to Association for Healthcare Philanthropy's Annual 'Report on Giving' 2Health News:Philanthropic Giving for Health Care Slows in 2006 in both U.S. and Canada, According to Association for Healthcare Philanthropy's Annual 'Report on Giving' 3
... Many special order products are offered ... extra long lengths. The modular instruments may ... other options such as ratchets, insulation and ... from Mediflex stock. Customer specifications may affect ...
... Many special order products are offered ... extra long lengths. The modular instruments may ... other options such as ratchets, insulation and ... from Mediflex stock. Customer specifications may affect ...
... offered as 1-piece or modular, in regular ... may be customized with handles of choice ... and flush ports. Many standard patterns are ... affect delivery times. , Please Note: ...
... Many special order products are offered as ... long lengths. The modular instruments may be ... options such as ratchets, insulation and flush ... Mediflex stock. Customer specifications may affect delivery ...
Medicine Products: