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SuperGen to Highlight Oncology Pipeline Data in Multiple,Presentations at AACR

DUBLIN, Calif., April 04, 2007 /PRNewswire-FirstCall/ -- SuperGen Inc. announced today that it will have multiple presentations at the American Association for Cancer Research Annual Meeting on April 14-18 in Los Angeles. These presentations will focus on data concerning many of SuperGen's current oncology programs including its lead tyrosine kinase inhibitor compound, MP470 and its ability to block Rad51, a key protein target involved in cancer cell drug resistance. Presentations will take place in the exhibit hall of the Los Angeles Convention Center.

    The schedule of SuperGen's presentations is:


                                                              Poster

    Date     Time (PDT)           Title                       Number/Section


    Sunday,   1 p.m. - 5 p.m.     Hydrochloride salt of       #1540

    April                         MP470, a potent

    15                            suppressor of Rad51,        Poster

                                  improves                    Section 31

                                  bioavailability and

                                  tolerability


    Monday,   8 a.m. - 12 p.m.    Discovery and               #2380

    April                         characterization of a

    16                            series of Axl kinase        Poster

                                  inhibitors using the        Section 30

                                  CLIMB(TM) process


    Monday,   8 a.m. - 12 p.m.    Discovery and               #2387

    April                         characterization of

    16                            small molecule              Poster

                                  inhibitors for Jak2         Section 30


    Monday,   8 a.m. - 12 p.m.    Zebrafish as a model        #2229

    April                         mechanistic screen

    16                            for small molecule          Poster

                                  inhibitors of DNMT1         Section 23



    Monday,   1 p.m. - 5 p.m.     Discovery and               #3261

    April                         development of MP529,

    16                            a new effective and         Poster

                                  selective inhibitor         Section 29

                                  of Aurora A kinase


    Tuesday,  8 a.m. - 12 p.m.    MP470, a potent             #4028

    April                         suppressor of Rad51,

    17                            improves response to        Poster

                                  platinum-based              Section 29

                                  anticancer agents





    Tuesday,  10:40 a.m. -        Novel DNA                   #4142

    April     10:55 a.m.          hypomethylating

    17                            agents: non-                Minisymposium

                                  nucleoside compounds        Cancer

                                  that do not                 Epigenetics

                                  incorporate into DNA

                                  selectively induce          Room 304 A-C

                                  degradation of DNA

                                  methyltransferase I

                                  (DNMT1) in human

                                  cancer cells by the

                                  proteasomal pathway

                                  and re-express

                                  silenced tumor

                                  suppressor genes


    Wed.,    8 a.m. - 12 p.m.     Dual inhibition of          #5421

    April                         receptor tyrosine

    18                            kinases of PDGFR and        Poster

                                  EGFR abolishes              Section 20

                                  prostate cancer cell

                                  growth in culture and

                                  in a mouse xenograft

              
                    model by complete

                                  dephosphorylation of

                                  PKB/Akt


    About SuperGen

Based in Dublin, Calif., SuperGen is a pharmaceutical company dedicated to the discovery, acquisition, rapid development and commercialization of therapies for solid tumors and hematological malignancies. SuperGen is developing a number of therapeutic anticancer products focused on inhibitors of aurora-A, tyrosine kinase and DNA methyltransferase. For more information about SuperGen, please visit http://www.supergen.com.

This news release contains certain "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements are typically preceded by words such as "believes," "expects," "anticipates," "intends," "will," "may," "should," or similar expressions. These forward-looking statements are not guarantees of future performance and involve a number of risks and uncertainties that may cause actual results to differ materially from the results discussed in these statements. Factors that might cause the company's results to differ materially from those expressed or implied by such forward-looking statements include, but are not limited to, the ability to discover, develop and move target compounds into clinical development and other risks and uncertainties detailed from time to time in the company's filings with the Securities and Exchange Commission including its most recently filed Form 10-Q and 10-K. SuperGen, Inc. undertakes no duty to update any of these forward-looking statements to conform them to actual results.

    Contacts:

    SuperGen                                Noonan Russo

    Timothy L. Enns                         Greg Geissman

    S.V.P., Corporate Communications        Director of Media Relations

    
& Business Development

    (925) 560-0100 x111                     (619) 814-3510

                          

tenns@supergen.com greg.geissman@eurorscg.com

CONTACT: Timothy L. Enns, S.V.P., Corporate Communications & BusinessDevelopment, of SuperGen, +1-925-560-0100 x111, ; or GregGeissman, Director of Media Relations, of Noonan Russo, +1-619-814-3510, tenns@supergen.com greg.geissman@eurorscg.com

Web site: http://www.supergen.com/

Ticker Symbol: (NASDAQ-NMS:SUPG)

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