Navigation Links
Study Sheds Light on Medication Treatment Options for Bipolar,Disorder

BETHESDA, Md., March 29, 2007--For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine. The results are part of the large-scale, multi-site Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), a $26.8 million clinical trial funded by the National Institutes of Healths National Institute of Mental Health (NIMH).

Bipolar disorder (http://www.nimh.nih.gov/healthinformation/bipolarmenu.cfm), a sometimes debilitating illness marked by severe mood swings between depression and mania, is usually treated with mood stabilizers such as lithium, valproate, carbamazepine or other medications that reduce mania. However, depression is more common than mania in bipolar disorder, and depressive episodes tend to last longer than episodes of mania. Antidepressant medications are often used in addition to a mood stabilizer for treating bipolar depression, but they are thought to confer a serious risk of a switch from a depressive episode to a manic episode.

Finding the right treatment balance for people with bipolar disorder is a constant challenge; STEP-BD aims to identify the best treatment options. Treating depression in people with bipolar disorder is notoriously difficult, said NIMH Director Thomas R. Insel. STEP-BD sought to determine if adding an antidepressant to a mood stabilizer is effective and safe in treating depressive episodes. The results suggest that antidepressants are safe but not more effective than placebo as assessed in a large number of people with bipolar disorder.

Lead author Gary Sachs, M.D., of Massachusetts General Hospital and colleagues studied 366 participants at 22 sites a
'"/>




Page: 1 2 3

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. Reaction to Avandia Warnings Stronger Among Internists Than Endocrinologists, According to Study by GfK Market Measures
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
8. Protox Announces Positive Clinical Data from Prostate Cancer Study
9. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
10. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
11. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
Post Your Comments:
(Date:4/17/2015)... Apr. 16, 2015 Research and Markets ... of the "The Corporate Reputation of Pharma ... Edition " report to their offering. ... Perspective, is now in its fourth edition. This ... early 2015). For each annual Corporate Reputation report, ...
(Date:4/17/2015)... 17, 2015 Bionomics Limited (ASX:BNO, ADR:BMICY), a ... innovative therapeutics for the treatment of cancer and diseases ... of data from three of its most advanced oncology ... (AACR) 106 th Annual Meeting being held from ... USA. The presentation on the ...
(Date:4/16/2015)... China , April 16, 2015 ... leading developer, manufacturer, and marketer of medical devices ... the Securities and Exchange Commission an Annual Report on ... the year ended December 31, 2014. An electronic version ... available on Mindray,s investor relations website at  http://ir.mindray.com ...
Breaking Medicine Technology:The Corporate Reputation of Pharma - The Global Patient Perspective in 2014 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5Mindray Files Annual Report on Form 20-F with the U.S. Securities and Exchange Commission 2
... Nov. 11, 2010 /PRNewswire-Asia-FirstCall/ -- American Oriental Bioengineering, ... or "AOBO"), a pharmaceutical company dedicated to improving ... a broad range of prescription and over-the-counter ("OTC") ... Wujia Rongxue Oral Liquid, ("AWRO Liquid"), an OTC ...
... Nov. 11, 2010 Misonix, Inc. (Nasdaq: ... ultrasonic medical device technology, which worldwide is used for ... quarter ended September 30, 2010 financial results on Monday, ... Executive Officer and Richard Zaremba, Senior VP and Chief ...
Cached Medicine Technology:American Oriental Bioengineering Introduces Wujia Rongxue Oral Liquid 2Misonix Schedules First Quarter 2011 Financial Results Conference Call; November 15, 2010 at 4:30 P.M. Eastern 2
(Date:4/18/2015)... "I wanted to live a healthier ... juice that contained essential vitamins, minerals and nutrients," ... my energy, improves skin elasticity and gives me ... Juice to contain fruits, vegetables and other healthful ... mental fatigue. It features a great taste. The ...
(Date:4/18/2015)... April 18, 2015 Lowcostcarinsuranceprice.com has released ... rates have on auto insurance prices . ... rates of vehicle theft may have to pay more ... liability auto insurance policies can also offer protection against ... now be compared online on a single website: ...
(Date:4/18/2015)... York (PRWEB) April 18, 2015 Thousand ... filed on behalf of individuals who were allegedly harmed ... continue to move forward in the U.S. District Court, ... April 10th, the Court has amended an earlier Case ... cases. Among other things, the new amendment permits the ...
(Date:4/18/2015)... On April 14th, 2015, Symantec released Volume ... say, “exposes a tactical shift by cyberattackers.” With everything from ... in 2014 - almost a million a day - to ... identified and patched by prominent manufacturers – as long as ... in a digital world can be fraught with peril, and ...
(Date:4/18/2015)... PHOENIX, ARIZONA – In March, Mark ... other secure destruction professionals across the United States, earned ... will now display “CSDS” as a professional title with ... National Association of Information Destruction 2015 Annual Conference began ... Of the 20 people who took the exam, Ona ...
Breaking Medicine News(10 mins):Health News:High Rates Of Car Theft Can Have An Impact on Auto Insurance Prices! 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 2Health News:DePuy Pinnacle Hip Lawsuits: Federal Litigation Amends Case Management Order to Allow for Joinder of Unrelated Claims 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5
... The Population Health Impact,Institute (PHII), a non-profit 501(c)(3) ... Workshop on June 19th entitled,"Giving Credit Where Credit ... Calculating,Clinical and Financial Outcomes Based Upon the Methods ... with the Case Management,Society of America (CMSA) Annual ...
... The Epilepsy,Foundation today released important information about epilepsy ... of recent news about,Senator Edward Kennedy (D-Mass)., Senator ... U. S.,Senate, reportedly experienced a seizure on Saturday. A ... brain. One in ten Americans,will have a single seizure ...
... TORONTOThe goal of developing reliable genetic tests to guide ... at Columbia University recently evaluated the ability of five ... that cancer would recur in patients whose non-small cell ... will present their findings at the American Thoracic Societys ...
... Report Outlines Retirement Risks and Identifies ... Approaches to Manage Those Risks, SCHAUMBURG, Ill., ... the unprecedented cost of gas, inflation is affecting every,American. Among the ... to retirement and current retirees who are experiencing,soaring costs in a ...
... The Natural Marketing,Institute,s (NMI) Health & Wellness ... to suffer from digestive disorders than men. No ... hormones, stress, diet, or all,three., Preliminary research ... gastrointestinal problems. The studies show transit time,slows significantly ...
... AMDL, Inc. (Amex:,ADL), ( http://www.amdl.com ), a ... Jiangxi and Jilin, China, announced today its,chief executive ... scheduled for Wednesday, May 21, at 1:15 p.m. ... quarter financial results., To access the live ...
Cached Medicine News:Health News:Population Health Impact Institute to Host First Methods Evaluation Process(TM) (MEP(TM)) Workshop at Annual CMSA Conference 2Health News:The Epilepsy Foundation Sheds Light on Seizures 2Health News:Will lung cancer recur? A genetic test may provide the answer 2Health News:Inflation Ranks as Today's Top Retirement Concern 2Health News:Inflation Ranks as Today's Top Retirement Concern 3Health News:Inflation Ranks as Today's Top Retirement Concern 4Health News:Women's Health Crisis: GI Problems Common in Women 2Health News:AMDL Announces Teleconference and Audio Web Conference to Discuss First Quarter Financial Results 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: