( al information about rupture-proneplaq...)Study Presented at the ACC Shows Inflammatory Enzyme Lp-PLA2,Predicts Heart Disease Risk in Metabolic Syndrome Patients,Health

A second study presented at the meeting focused on treatment of 55 metabolic syndrome patients with elevated levels of Lp-PLA2 and triglycerides. The results presented by Dr. Robert Rosenson of the University of Michigan showed that three months of treatment with fenofibrate (160 mg/day) reduced Lp-PLA2 levels measured with the PLAC test. Lanman said these findings highlight the opportunity for plaque stabilization with lipid-modifying medication when patients with the metabolic syndrome also have elevated Lp-PLA2. "The PLAC test identifies patients who benefit from lipid-modifying therapy such as fenofibrate to help prevent cardiovascular events," he said.

diaDexus, Inc., a privately held biotechnology company based in South San Francisco, Calif., is focused on the discovery, development, and commercialization of innovative, patent-protected diagnostic products with high clinical value. The PLAC test is a simple blood test that has been cleared for marketing by the Food and Drug Administration as an aid in predicting risk for coronary heart disease and ischemic stroke associated with atherosclerosis. In addition to the PLAC test, diaDexus is developing a pipeline of novel cancer diagnostic tests. For information, visit www.plactest.com or www.diaDexus.com.

Note to editors: The American College of Cardiology's 56th annual scientific session is being held at the Ernest N. Morial Convention Center in New Orleans, March 24-27, 2007. diaDexus' booth number is 1232. For copies of the abstracts, please contact Barbara Sullivan at 714/374-6174.

Contact

Sullivan & Associates
Barbara Sullivan, 714-374-6174
bsullivan@sullivanpr.com
or
diaDexus, Inc.
Christina Andrian, 650-246-6476'"/>