Navigation Links
Study Demonstrated Rozerem (ramelteon) Does Not Affect,Middle-of-the-Night Balance in Older Adults with Insomnia

. However, the positive control, zopiclone, did show a statistically significant difference versus placebo at near-peak plasma levels, indicating impairment in body sway. Specific findings showed that the mean log of COP post-dose for placebo was 1.617 cm2 and for ROZEREM 1.497 cm2, (P=0.532). For zopiclone the mean log of COP after dosage was 3.539 cm2, (P<0.001) compared to placebo.

ROZEREM Study Design 2: Middle-of-the-Night Balance, Mobility or Memory Performance

This study evaluated the effects of ROZEREM versus placebo on middle-of- the-night balance, mobility and memory performance in older adults with chronic insomnia, with zolpidem as a positive control. A total of 33 adults age 65 or older with chronic insomnia received ROZEREM 8 mg, zolpidem 10 mg or placebo 30 minutes before bedtime for one night each in this double-blind, placebo-controlled study. Patients were awakened two hours after they were given medication to evaluate standing balance, turning speed and stability, memory and adverse events. The primary endpoint was balance as assessed by NeuroCom EquiTest Sensory Organization Test (SOT) score two hours after dosage. An SOT objectively identifies abnormalities in patients' use of the three sensory systems that contribute to postural control.

Results found that compared to placebo, ROZEREM did not impair middle-of- the-night balance, mobility or memory performance in older adults with chronic insomnia, relative to the positive control zolpidem. A significant decrease in mean SOT composite score was observed between zolpidem and placebo (P<0.001), but not between ROZEREM and placebo (P=0.837). As compared to placebo, ROZEREM results showed:

    -- No significant increase in turn time and turn sway (P=0.776, P=0.982,

       respectively)

    -- Immediate memory recall did not decline significantly (P=0.683)


    As compared to placebo, zolpidem results showed:


    -- Significant increase in turn time and turn sway (
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. Reaction to Avandia Warnings Stronger Among Internists Than Endocrinologists, According to Study by GfK Market Measures
6. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
8. Protox Announces Positive Clinical Data from Prostate Cancer Study
9. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
10. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
11. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
Post Your Comments:
(Date:12/24/2014)... , Dec. 24, 2014 Kinex Pharmaceuticals announced ... KX2-361 at Roswell Park Cancer Institute. KX2-361 ... drug that has shown potent inhibitory activity against a ... that are resistant to Temozolomide (T98G), the most widely ... a well-established brain tumor mouse model, KX2-361 consistently clears ...
(Date:12/24/2014)... FARMINGTON, Conn. , Dec. 24, ... PTN), a biopharmaceutical company developing targeted, receptor-specific peptide ... unmet medical need and commercial potential, today announced ... of 2,050,000 shares of its common stock and ... its common stock.  Funds under the management of ...
(Date:12/24/2014)... DIEGO , Dec. 23, 2014 ResMed (NYSE: ... significant patent infringement action against Chinese medical device manufacturer BMC ... (ITC) ruled today that BMC,s masks listed below infringe ResMed,s ... or selling these masks in the United States ... iVolve N2 nasal mask , Willow nasal pillows mask ...
Breaking Medicine Technology:Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 2Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 4ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2
... HealthWarehouse.com , Inc. (OTC: HEWA), a leading ... its pre-order program to enable consumers immediate access to Atorvastatin ... offer the medication at up to 50 percent less ... "We will be one of the earliest and ...
... Nov. 29, 2011  In a new study presented today at ... (RSNA), growth hormone replacement for six months was found to ... is the first time that the effects of growth hormone ... lead author, Miriam A. Bredella, M.D., a radiologist at Massachusetts ...
Cached Medicine Technology:HealthWarehouse.com Offers Lowest Price Generic Lipitor on the Market 2HealthWarehouse.com Offers Lowest Price Generic Lipitor on the Market 3Growth Hormone Increases Bone Formation in Obese Women 2
(Date:12/25/2014)... Carolina (PRWEB) December 25, 2014 ... Carolina Retirement Community, recently showed their generous spirit ... of the Catawba County Parenting Network- Grandparents Raising ... 10 children gathered around the largest Christmas tree ... open presents purchased by residents of the Abernethy ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping those in the ... holiday season, AlignLife looks forward to their annual toy drive. ... Mahalko-Leonhardt, owner of AlignLife. "It brings our patients as well ... able to give kids toys for Christmas who would be ... of our patients." , The 70 toys were donated to ...
(Date:12/24/2014)... December 24, 2014 Connie Casad, MD, ... functional medicine advocate with 30 years of practice experience ... evaluate the health benefits of dietary detoxification. The second ... participants following excellent results from test patients who just ... to explain her interest in conducting the study, Dr. ...
(Date:12/24/2014)... 2014 New studies reveal that women under ... related depression (March 6, 2014, JAMA Otolaryngology*). And although many ... (about 50 percent according to recent polls) facing hearing loss ... a person feels and relates to the world. People who ... also made by way of:, , self-confidence ...
(Date:12/24/2014)... Today, UWDress.com, the famous women’s dress supplier, has presented ... a site-wide wedding gown promotion. , For those ... more unexpected way, the collection should be a great choice. ... market, and they are available with custom service. , Now, ... prices, up to 75% off; most of them come in ...
Breaking Medicine News(10 mins):Health News:Retirement Community Residents Make Impact During Holiday Season 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 2Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 4Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 5Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 6Health News:Buy Cheap Long Sleeve Wedding Gowns At UWDress.com 2
... HCA today announced financial,and operating results for the third quarter ... increased 5.7 percent to $6.569 billion. -- Adjusted EBITDA totaled ... the prior year. -- Net income totaled $300 million, ... year. -- Interest expense increased to $560 million, up from ...
... in 2008, HOUSTON, Nov. 7 In ... and RediClinic Services units of RediClinic,LLC have been ... have been promoted and two new executives have ... chief operating officer of the RediClinic,division, has been ...
... America, the premier network,of diabetes care and management centers ... its physicians have been recognized by the,Diabetes Physician Recognition ... Dr. Wendy Hawkins M.D., Dr. Damon,Weddington M.D., Dr. Alice ... M.D. were all honored in Houston today. "The ...
... Inc. (Amex:,ADL), with operations in Shenzhen, Jiangxi and ... Inc. (JPI), which is an,international biopharma company that ... pharmaceutical and diagnostic,products, announced today that JPI,s subsidiary ... agreements for its new anti-aging and skin,care injectable ...
... at 8:00 a.m. ET -, VALENCIA, Calif., Nov. ... financial results for the third quarter ended,September 30, 2007. ... expenses were $75.6,million, compared to $61.1 million for the ... was attributed to increased research,and development (R&D) expenses which ...
... Insulet Corporation,(Nasdaq: PODD ), the manufacturer and marketer ... of its public offering of,4,898,398 shares of common stock ... by selling stockholders. Insulet will not receive any proceeds,from ... has granted to,the underwriters an option to purchase up ...
Cached Medicine News:Health News:HCA Reports Third Quarter 2007 Results 2Health News:HCA Reports Third Quarter 2007 Results 3Health News:HCA Reports Third Quarter 2007 Results 4Health News:HCA Reports Third Quarter 2007 Results 5Health News:HCA Reports Third Quarter 2007 Results 6Health News:HCA Reports Third Quarter 2007 Results 7Health News:HCA Reports Third Quarter 2007 Results 8Health News:HCA Reports Third Quarter 2007 Results 9Health News:HCA Reports Third Quarter 2007 Results 10Health News:HCA Reports Third Quarter 2007 Results 11Health News:HCA Reports Third Quarter 2007 Results 12Health News:HCA Reports Third Quarter 2007 Results 13Health News:HCA Reports Third Quarter 2007 Results 14Health News:RediClinic Announces Management Changes 2Health News:RediClinic Announces Management Changes 3Health News:Diabetes America Physicians Achieve Industry Recognition for Quality Patient Care 2Health News:AMDL Launches Expanded Distribution With 4th Round of Agreements Valued at $6.79 Million Annually for New Health & Beauty Product Line 2Health News:MannKind Corporation Reports Third Quarter Financial Results 2Health News:MannKind Corporation Reports Third Quarter Financial Results 3Health News:MannKind Corporation Reports Third Quarter Financial Results 4Health News:MannKind Corporation Reports Third Quarter Financial Results 5Health News:MannKind Corporation Reports Third Quarter Financial Results 6Health News:Insulet Corporation Announces Pricing of Secondary Public Offering 2
Tips are sharp on both sides to puncture, cut and tear the capsule...
...
...
... StressVue puts leading-edge stress testing within ... office or clinic to the most advanced ... vivid flat panel monitor with options for ... thermal printer for continuous printing. StressVue is ...
Medicine Products: