Navigation Links
Solstice Neurosciences Presents Escalating Dose Study at,International Congress in Istanbul, Turkey

MALVERN, Pa., June 15, 2007 /PRNewswire/ -- Solstice Neurosciences, Inc. today reported important results from a multicenter, forced dose escalation study of Botulinum Toxin Type B Injectable Solution (Myobloc(R)) recently presented at the 11th International Congress of The Movement Disorders Society in Istanbul, Turkey.

This was the first multicenter study to confirm patient safety and efficacy of escalating treatment doses of 10,000 Units, 12,500 Units, and 15,000 Units of Botulinum Toxin Type B in patients with cervical dystonia (CD).

The study results were presented by Eric J. Pappert, MD, who is assistant professor of neurology and director of the Parkinson's Disease and Movement Disorders Program at the University of Texas Health Science Center in San Antonio, Texas. Dr. Pappert also serves as Vice President, Medical & Scientific Affairs of Solstice Neurosciences.

"The recommended initial dose of Type B Toxin for patients with a prior history of tolerating botulinum toxin injections is 2,500 to 5,000 Units, with subsequent dosing to be optimized according to individual patient response. Pivotal clinical trials have used doses of 5,000 and 10,000 Units," said Dr. Pappert. "So, these data provide important insights for understanding how patients respond to higher doses. The results will also help guide the design of future studies."

    Highlights from the open-label study included the following:


    -- 145 Subjects (95% Caucasian, 65% Female, Mean Age=53.1 years)

    -- Previous experience with neurotoxins

       -- Resistant to Type A (n=32; 22%)

       -- Responsive to Type A (n=113; 78%)

    -- Treatment: 3 escalating doses (10,000 Units, 12,500 Units, 15,000

       Units)

    -- Measurement intervals: baseline, 2 weeks, every 4 weeks

    -- Effectiveness measurements:

       -- Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) Total

          Score (Torticollis Severity, Disability, Pain)

       --
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
3. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
4. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
5. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
6. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
7. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
8. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
9. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
10. DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of Improved Glycemic Control and Significant Reductions of LDL-Cholesterol and C-Reactive Protein
11. BioCryst Presents Phase I Peramivir Data at the Options for the Control of Influenza Conference
Post Your Comments:
(Date:8/27/2015)... DURECT Corporation (Nasdaq: DRRX ) announced ... upcoming healthcare conferences.  , James ... the Rodman & Renshaw Investment Conference on Thursday, September ... being held at the St. Regis Hotel in ... webcast of the presentation will be available by accessing ...
(Date:8/27/2015)... , August 27, 2015 According to a ... Hammock, Toilet, Seating, Universal, Standing, Bariatric ), Material (Nylon, Padded, Canvas), ... to 2020", published by MarketsandMarkets, the Medical Lifting Sling Market is ... Million in 2015, at a CAGR of 11.4 % from 2015 ... ma rket data T ables and ...
(Date:8/27/2015)... --  Women Grow , the fastest-growing professional networking organization for ... Cannabis World Congress & Business Exposition (CWCBExpo) in ... educational sessions. CWCBExpo in LA will take place September 16-18, ... Center in Los Angeles, CA , and ... the marijuana industry. The Women Grow tracks at ...
Breaking Medicine Technology:DURECT to Participate in Upcoming Healthcare Conferences 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 3Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 4
... Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced the ... direct oral once-daily Factor Xa inhibitor, significantly reduced the ... or hip arthroplasty, when compared to enoxaparin. Patients receiving ... deep vein thrombosis (DVT) and pulmonary embolism (PE) than ...
... /PRNewswire-Asia/ -- WuXi PharmaTech (NYSE: WX ), ... outsourcing company with operations in China and the United ... Science and Chemistry Awards, held on December 12, 2011 ... theme of this year,s awards was Disease Biology. Guowei ...
Cached Medicine Technology:Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery 2Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery 3Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery 4Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery 5WuXi PharmaTech Presents the 2011 Life Science and Chemistry Awards 2WuXi PharmaTech Presents the 2011 Life Science and Chemistry Awards 3
(Date:8/27/2015)... ... 27, 2015 , ... About 10 percent of mothers experienced ... Coast, killing more than 1,800 people, displacing hundreds of thousands and causing widespread ... study. , While most people don’t develop persistent depression after a major disaster ...
(Date:8/27/2015)... ... August 27, 2015 , ... The Naderi Center is proud to announce that ... noninvasive procedure to improve submental fat. The first and only Food and Drug ... Dr. Kulak is the only Board Certified surgeon in the D.C., Maryland, Virginia ...
(Date:8/27/2015)... ... 27, 2015 , ... StayWell, a leading provider of patient ... ICD-10 ready and available to all clients. All Krames Patient Education content has ... more targeted and return a more comprehensive data set of content than the ...
(Date:8/27/2015)... ... August 27, 2015 , ... Zensah®, ... Glushko, professional Tennis player for Israel in the Women’s Tennis Association (WTA). Glushko ... her training and recovery. , With a focus on technology and comfort, Zensah® ...
(Date:8/27/2015)... ... August 27, 2015 , ... In addition to its existing Doctor of Philosophy ... doctoral program at its main campus in Reading: Doctor of Nursing Practice. , Alvernia’s ... prepare advanced practice nurses for the highest level of clinical nursing practice. , ...
Breaking Medicine News(10 mins):Health News:About 10 Percent of Mothers Experienced Depression Two Years After Hurricane Katrina, New Study Shows 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 3Health News:StayWell announces all health content is ICD-10 ready 2Health News:StayWell announces all health content is ICD-10 ready 3Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 2Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 3Health News:Alvernia University Now Offering Three Doctoral Degree Programs 2
... preparation developed by University of Minnesota researchers could put ... infection caused by the bacterium Clostridium difficile . ... will continue to work with the university to advance ... eventually, encapsulated preparations. C. difficile affects ...
... May 16 (HealthDay News) -- Dinosaurs may have suffered ... specimen of a pliosaur, researchers from University of Bristol ... a degenerative condition similar to human arthritis. Specifically, the ... left jaw joint. Pliosaurs were marine predators with ...
... Mo. Apigenin, a natural substance found in grocery store ... aggressive form of human breast cancer, following a new study ... a type of breast cancer tumor that is stimulated by ... related to menopause. "This is the first study to ...
... cell surface protein that is part nametag and part bull,s ... vulnerability to a drug, researchers at The University of Texas ... Clinical Investigation . "We,ve discovered the first single marker ... targetable with a small molecule drug that inhibits an enzyme ...
... -- Black and Hispanic Americans are far more likely than ... Researchers analyzed data from more than 5,000 men and ... screening at New York-Presbyterian Hospital/Columbia University Medical Center in New ... had signs or symptoms of colorectal (colon) cancer at the ...
... -- Researchers are preparing to test an experimental drug in ... hope is that the drug will lead to a way ... understanding of its destructive processes, U.S. officials announced Tuesday. ... as 300 members of an extended Colombian family -- some ...
Cached Medicine News:Health News:University of Minnesota startup to treat challenging bacterial infection 2Health News:Dinosaurs May Have Suffered From Arthritis 2Health News:Breast cancer effectively treated with chemical found in celery, parsley by MU researchers 2Health News:Scientists discover marker to identify, attack breast cancer stem cells 2Health News:Scientists discover marker to identify, attack breast cancer stem cells 3Health News:Scientists discover marker to identify, attack breast cancer stem cells 4Health News:Blacks, Hispanics Have Higher Colon Polyp Risk Than Previously Thought 2Health News:Trial Set to See if Drug Can Prevent Alzheimer's 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: