Navigation Links
Soliris Effective in PNH Patients With History of Aplastic Anemia,and Myelodysplastic Syndromes

al Sloan-Kettering Cancer Center. "The EXPLORE study will help hematologists-oncologists better understand the prevalence and clinical characteristics of PNH in patients with bone marrow disorders. Many of these patients may benefit from treatment with Soliris. Data from EXPLORE may also help us define and implement screening protocols for PNH."

PNH is a rare, disabling and life-threatening blood disorder defined by chronic red blood cell destruction, or hemolysis. Hemolysis can cause one or more of the following symptoms in patients with PNH: severe anemia, disabling fatigue, recurrent pain, shortness of breath, pulmonary hypertension, intermittent episodes of dark colored urine (hemoglobinuria), kidney disease, impaired quality of life and blood clots (thromboses).(1)(2)

PNH has been identified more commonly among patients with disorders of the bone marrow, including AA and MDS.(3)(4)(5)(6) Underlying bone marrow dysfunction can complicate the clinical course of PNH, contributing to anemia, a greater dependence on transfusion support, an increased risk of infection and life-threatening hemorrhage.(7) AA occurs when the bone marrow stops making enough blood-forming stem cells. MDS occurs when the bone marrow and stem cells malfunction, resulting in the production of too many defective blood cells and not enough normal blood cells.

Data Presented at ASCO

Researchers conducted an analysis of data from the Phase III TRIUMPH and SHEPHERD clinical trials to evaluate the safety and efficacy of Soliris treatment over 26 weeks in 39 patients who were diagnosed with PNH and who had a history of AA or MDS. Among these patients, hemolysis was reduced by 84 percent, compared with an 85 percent reduction among patients without a history of AA or MDS. Anemia was also significantly reduced in these patients, as transfusions of packed red blood cells (RBCs) were reduced from a median of seven units/patient prior to treatment to zero units/patient while
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Studies Show Efficacy and Safety of Alexions Soliris in Broad Population of PNH Patients
2. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
3. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
4. Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
5. Gabapentin Shown Effective for Fibromyalgia Pain
6. ApoCells Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
7. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
8. XYOTAX More Cost Effective With Fewer Side Effects Than Gemcitabine or Vinorelbine in Treating Non-Small Cell Lung Cancer
9. Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and Effective in Colorectal Cancer with Liver Metastases
10. Biotheras Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
11. Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
Post Your Comments:
(Date:3/31/2015)... -- Ariana Smith, a 17-year-old Taylor teen, became the first patient ... a part of the Detroit Medical Center (DMC), and the ... a revolutionary 3D printed heart model to aid heart specialists ... In November, 2014, Ariana,s mom Jacqueline Foster ... a test that checks for problems with the electrical activity ...
(Date:3/31/2015)... ALPHARETTA, Ga. , March 31, 2015   ... Health Care, today announced it was awarded a new ... line of face masks. Effective March 1, 2015, Halyard,s ... masks with SO SOFT* lining, will be available to ... as well as 15,000 ambulatory surgery centers, physician practices ...
(Date:3/31/2015)... VICTORIA, BC , March 31, 2015 /CNW/ - T-Bird ... company focused on developing premium quality medical marijuana products ... the Marihuana for Medical Purposes Regulations ( Canada ... has received notice from The Corporation of the District ... rezoning approval of the Company,s premises which now allows ...
Breaking Medicine Technology:Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 2Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 3Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 4Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 5Halyard Health Signs First GPO Contracts As Independent Company 2Halyard Health Signs First GPO Contracts As Independent Company 3T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 2T-Bird Pharma Inc. Announces Final Municipal Rezoning Approval 3
... 29, 2011 Professional and Trade Relations groups play ... to professional, payer and patient groups. However, today,s restrictive ... PTR activities - thus creating pressure on PTR groups ... optimize their impact.   Recognizing changing needs ...
... Centocor Ortho Biotech Products, L.P., today announced that ... for trabectedin for the treatment of women with recurrent ... U.S. Food and Drug Administration,s (FDA) recommendation that an ... The NDA was submitted to the FDA ...
Cached Medicine Technology:Professional Relations Excellence Outlined in New Best Practices, LLC Report 2Centocor Ortho Biotech Products, L.P. Voluntarily Withdraws NDA for Trabectedin 2
(Date:3/31/2015)... Dr. Parsa Mohebi, founder of Parsa Mohebi Hair Restoration ... forefront of using beard hair to fill in balding ... novelty has now become an absolute option for giving patients the ... do believe that beard to scalp hair transplant can be a ... isn’t as dense as we would like it,” says Dr. Parsa ...
(Date:3/31/2015)... Calling all runners, walkers and everyone who wants to join ... annual “Lyme Walk & Run” will be held Sunday, April ... hosted by Lyme Research Alliance (LRA) & Tick-Borne ... and education about Lyme and other tick-borne diseases. , ... feature 5K and 10K runs and one-mile and three-mile Walks ...
(Date:3/31/2015)... OnChip Devices , a world leader in Integrated ... chip targeted towards low voltage LED applications. Adding to its ... for protecting circuits by suppressing voltage higher than 3.0 Volts. ... up to 350W and 20A, providing protection of 8kV when ... These diodes do not exhibit any device degradation when compared ...
(Date:3/31/2015)... March 31, 2015 Dr. ... by the American Board of Dermatology and fellowship ... research training at the National Cancer Institute of ... his internship in internal medicine at the Emory ... Pennsylvania in Philadelphia. Dr. Li pursued further training ...
(Date:3/31/2015)... Dr. Uzma Parvez is having a busy start ... Grand Grounds Presentations at St. Michael’s Medical Center for attending ... The event was attended by a large gathering of ... feedback from the Grand Rounds. It was said that ... a while. , Ahead, Dr. Parvez has been invited ...
Breaking Medicine News(10 mins):Health News:Is Beard to Scalp Hair Transplant the Future? 2Health News:Lyme Research Alliance & Tick-Borne Disease Alliance to Kick-Off 1st “Lyme Walk & Run” Event, April 26 2Health News:OnChip Introduces Low Voltage Diodes for High-Brightness LED Protection 2Health News:Dr. Andrew Li of Warren Skin Care Center Is Celebrating 3 Years Recognized as an "NJ Top Doc" 2Health News:NJ Top Docs Presents, Dr. Uzma Parvez of Total Pain Care 2
... AEGON N.V.,and the international humanitarian organization Right ... the organization,s mission to help,children in deprived areas ... donated EUR 1 million as part of a ... Winter Olympic games in Vancouver, Canada., (Photo: ...
... benefit from further study of vitespen, researchers say , , ... vitespen didn,t increase recurrence-free survival among kidney cancer patients ... standard treatment for kidney cancer, but many patients are ... effective adjuvant treatment, according to background information in the ...
... at work, one expert says , , THURSDAY, July 3 (HealthDay ... man,s chances of developing erectile dysfunction, Finnish researchers report. , ... body. It,s what we in vascular surgery refer to as ... Sadeghi-Nejad, an associate professor of urology at UMDNJ New Jersey ...
... director of the National Alliance on Mental Illness ... the lives,of individuals and families affected by mental ... monitor the callous treatment and tragic death of,Ms. ... the psychiatric,ward at Kings County Hospital in Brooklyn, ...
... Renowned stroke researcher Dr. Vladimir Hachinski has been named ... for his lifetime contributions in the field of neurology. ... University of Western Ontario in the Department of Clinical ... Dentistry. He is the founding and current chairman ...
... is a condition that unexpectedly and unexplainably takes the lives ... year. Now researchers of the European Molecular Biology Laboratory in ... crib or cot death, which remains the leading cause of ... The model, published in this week,s issue of Science ...
Cached Medicine News:Health News:AEGON and Right To Play Announce Global Partnership 2Health News:AEGON and Right To Play Announce Global Partnership 3Health News:Kidney Cancer Vaccine Shows No Boost in Survival 2Health News:Lots of Sex May Prevent Erectile Dysfunction 2Health News:Kings County Death: NAMI Calls for Criminal Probe; Survey Shows Psychiatric Emergency Room Delays Are National Problem 2Health News:Pioneering stroke researcher awarded Canada's highest honor 2Health News:New research sheds light on the molecular basis of crib death 2
Ishihara test chart book for color blindness. 14 plate. A simple accurate method for discovering congenital color blindness....
10 plate suitable for children and the illiterate....
Accepted by leading authorities as a simple and accurate method for discovering congenital color blindness of two type total color blindness and red/green blindness. This book is used for children an...
Stainless steel disposable retinal MVR blade, 10 pcs / box....
Medicine Products: