Navigation Links
Soliris Effective in PNH Patients With History of Aplastic Anemia,and Myelodysplastic Syndromes

- Analysis of Phase III Data Presented at ASCO -

CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- Investigators reported today that Soliris(TM) (eculizumab), a new treatment for paroxysmal nocturnal hemoglobinuria (PNH) developed by Alexion Pharmaceuticals, Inc. , is effective in patients diagnosed with PNH who have a history of aplastic anemia (AA) or myelodysplastic syndromes (MDS). Soliris significantly reduced red blood cell destruction (hemolysis), decreased or eliminated blood transfusion requirements, improved fatigue and quality-of- life outcomes, and reduced thrombotic events in PNH patients who have a history of either one of these bone marrow disorders, according to an analysis of Phase III data presented today at the 43rd annual meeting of the American Society of Clinical Oncology (ASCO).

"A growing body of evidence shows that all PNH patients have the potential to realize meaningful improvement with Soliris, regardless of symptoms, history of bone marrow failure, or transfusion needs prior to treatment," said Leonard Bell, MD, chief executive officer of Alexion Pharmaceuticals. "We believe these data will increase awareness of PNH among oncologists who specialize in bone marrow disorders and give them confidence to treat PNH patients with Soliris."

Alexion also announced today the expansion of an ongoing study to examine the frequency of PNH in patients with AA, MDS and other bone marrow disorders. Alexion now plans to enroll up to 10,000 patients in the EXPLORE trial (EXamination of PNH, by Level Of CD59 on Red and white blood cells, in bone marrow failure syndromes). Since beginning the EXPLORE trial in June 2006 with an initial target of 2,000 patients, Alexion has enrolled 1,500 patients.

"People with bone marrow disorders like AA and MDS are more likely to suffer from PNH," said Dr. Hugo Castro-Malaspina, Division of Bone Marrow Transplant and Hematology Services at Memori
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Studies Show Efficacy and Safety of Alexions Soliris in Broad Population of PNH Patients
2. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
3. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
4. Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
5. Gabapentin Shown Effective for Fibromyalgia Pain
6. ApoCells Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
7. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
8. XYOTAX More Cost Effective With Fewer Side Effects Than Gemcitabine or Vinorelbine in Treating Non-Small Cell Lung Cancer
9. Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and Effective in Colorectal Cancer with Liver Metastases
10. Biotheras Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
11. Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
Post Your Comments:
(Date:9/17/2014)... 2014  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or ... that address unmet medical needs in the areas ... agreement has been reached with the US Food ... a pivotal, Phase 3 clinical trial evaluating its ... cutaneous T-cell lymphoma (CTCL).  SGX301 ...
(Date:9/17/2014)... LAUSANNE , Switzerland , ... part of Debiopharm Group ™ , is proud to ... ™ instrument. Debiopharm Diagnostics is a long-time ... portfolio. Idylla ™ Biocartis, fully ... designed to offer physicians fast and easy access ...
(Date:9/16/2014)... Sept. 16, 2014 This report analyzes the worldwide ... the following Product Segments: SPECT Systems (Includes SPECT and SPECT/CT ... report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... and forecasts are provided for the period 2013 through 2020. ...
Breaking Medicine Technology:Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 2Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 3Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 4Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 5Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 6Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 7Debiopharm Diagnostics Portfolio Company Biocartis Ships its First Idylla Instrument 2Global Nuclear Medicine Imaging Equipment Industry 2Global Nuclear Medicine Imaging Equipment Industry 3Global Nuclear Medicine Imaging Equipment Industry 4Global Nuclear Medicine Imaging Equipment Industry 5Global Nuclear Medicine Imaging Equipment Industry 6Global Nuclear Medicine Imaging Equipment Industry 7Global Nuclear Medicine Imaging Equipment Industry 8Global Nuclear Medicine Imaging Equipment Industry 9Global Nuclear Medicine Imaging Equipment Industry 10Global Nuclear Medicine Imaging Equipment Industry 11Global Nuclear Medicine Imaging Equipment Industry 12Global Nuclear Medicine Imaging Equipment Industry 13Global Nuclear Medicine Imaging Equipment Industry 14Global Nuclear Medicine Imaging Equipment Industry 15Global Nuclear Medicine Imaging Equipment Industry 16Global Nuclear Medicine Imaging Equipment Industry 17Global Nuclear Medicine Imaging Equipment Industry 18Global Nuclear Medicine Imaging Equipment Industry 19Global Nuclear Medicine Imaging Equipment Industry 20Global Nuclear Medicine Imaging Equipment Industry 21Global Nuclear Medicine Imaging Equipment Industry 22Global Nuclear Medicine Imaging Equipment Industry 23Global Nuclear Medicine Imaging Equipment Industry 24Global Nuclear Medicine Imaging Equipment Industry 25Global Nuclear Medicine Imaging Equipment Industry 26
... 2011 Reportlinker.com announces that a new ... catalogue: Drug Delivery in ... companies http://www.reportlinker.com/p0203542/Drug-Delivery-in-Central-Nervous-System-Diseases---technologiesmarkets-and-companies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ... The delivery of drugs to central nervous ...
... 30, 2011 Reportlinker.com announces that a ... its catalogue: Cardiovascular Drug ... http://www.reportlinker.com/p0203538/Cardiovascular-Drug-Delivery---technologiesmarkets-and-companies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ... the cardiovascular system is different from delivery ...
Cached Medicine Technology:Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 2Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 3Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 4Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 5Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 6Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 7Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 8Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 9Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 10Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 11Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 12Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 13Cardiovascular Drug Delivery - Technologies, Markets and Companies 2Cardiovascular Drug Delivery - Technologies, Markets and Companies 3Cardiovascular Drug Delivery - Technologies, Markets and Companies 4Cardiovascular Drug Delivery - Technologies, Markets and Companies 5Cardiovascular Drug Delivery - Technologies, Markets and Companies 6Cardiovascular Drug Delivery - Technologies, Markets and Companies 7Cardiovascular Drug Delivery - Technologies, Markets and Companies 8Cardiovascular Drug Delivery - Technologies, Markets and Companies 9Cardiovascular Drug Delivery - Technologies, Markets and Companies 10Cardiovascular Drug Delivery - Technologies, Markets and Companies 11Cardiovascular Drug Delivery - Technologies, Markets and Companies 12Cardiovascular Drug Delivery - Technologies, Markets and Companies 13
(Date:9/17/2014)... By Steven Reinberg ... -- On the same day that President Barack Obama announced ... Africa,s Ebola crisis, the World Health Organization warned Tuesday that ... infections could start doubling every three weeks. Obama said ... offer medical and logistical support to beleaguered health care facilities ...
(Date:9/17/2014)... severe maternal morbidity amongst women in Australia is ... study published today (17 September) in BJOG: ... , Australians generally enjoy high standards of living; ... exist, in particular between indigenous and non indigenous ... the independent impact of socioeconomic position on severe ...
(Date:9/17/2014)... of a perfectly poured glass of wine leads to an ... Denmark, have now developed a nanosensor that can mimic what ... measures how you experience the sensation of dryness in the ... they need to control a number of processes to bring ... in the wine bottle. An important part of the taste ...
(Date:9/17/2014)... 17, 2014 MarijuanaStock.net, a cannabis ... recently launched a “Video” section that contains important ... in the marijuana industry made available in video ... visitor is given access to numerous interviews, news ... businesses and the issues they face. , ...
(Date:9/17/2014)... Fresh off their High Times Cannabis ... support of The Silver Tour, an educational non-profit effort ... benefits of medical marijuana. , Florida Buds, a Florida ... marijuana dispensary and treatment center, donated $1,000.00 to ... launch a statewide radio campaign in advance of Election ...
Breaking Medicine News(10 mins):Health News:Obama Steps Up Aid to Fight Ebola in West Africa 2Health News:Obama Steps Up Aid to Fight Ebola in West Africa 3Health News:New study examines the impact of socioeconomic position and maternal morbidity in Australia 2Health News:New study examines the impact of socioeconomic position and maternal morbidity in Australia 3Health News:Nanoscience makes your wine better 2Health News:Nanoscience makes your wine better 3Health News:MarijuanaStock.net Adds Business News Video Section to Their Website 2Health News:Florida Buds Supports Silver Tour 2
... Therapeutics Inc. (Nasdaq CM: CRTX), a specialty pharmaceutical company ... for the respiratory and related markets, today announced that ... Vice President, General Counsel and Secretary. In this ... team and manage its legal function and corporate governance ...
... ... Drug Administration approved the use of silicone implants for breast augmentation procedures in women over ... decision capped a controversy that spanned more than a decade, and one plastic surgeon ... , ...
... , ... 1-3 December at Olympia Grand Hall, London, ... across Mainland Europe with two brand new features -- The French ... France, and The European Librarians’ Theatre which hosts sessions on topical ...
... CHARLOTTE, N.C., Nov. 12 Even with the economy still ... - and in quite a creative way. , Southeast Pain ... Dec. 3 performance of "Grease" at Ovens Auditorium and giving ... , "We are committed to supporting our patients in ...
... INDIANAPOLIS, Nov. 12 Centerplate, the hospitality ... sports stadiums, announced today with the Capital Improvement ... investigation of Lucas Oil Stadium to immediately address ... facility operates as a model of operational excellence ...
... are highlights from the November issue of Mayo ... as often as you wish. Mayo Clinic ... Reprinting is allowed for a fee. Include the following ... www.bookstore.mayoclinic.com or call toll-free for subscription ...
Cached Medicine News:Health News:Cornerstone Therapeutics Appoints General Counsel 2Health News:Cornerstone Therapeutics Appoints General Counsel 3Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 2Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 3Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 4Health News:Online Information 2009 Exhibition Focuses on Mainland Europe 2Health News:Online Information 2009 Exhibition Focuses on Mainland Europe 3Health News:Southeast Pain Care Provides Relief and Gives Back - Creatively 2Health News:Centerplate and the Capital Improvement Board Investigating Food Safety Violations at Lucas Oil Stadium to Ensure Highest Standards Achieved and Operational Excellence 2Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 2Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 3Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 4Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 5
... Gemini is the newest addition to Laserscopes ... distinct wavelengths to choose from, 1064nm Nd:YAG ... in an exploding non-invasive aesthetic laser market ... and effectiveness while maintaining the safety and ...
... Surgical Laser System is designed for ... high-power, dual-wavelength system designed for urology, ... surgery, neurosurgery, pulmonary surgery and gastroenterology ... vaporizes and coagulates tissue with minimal ...
... biolitecs Ceralas D 980 nm diode laser ... bloodless field for most surgical procedures. ... cuts optically without collateral tissue damage ... coagulates blood instantly and seals small blood ...
... is a monoclonal antibody based ... confirmatory identification of Neisseria gonorrhoeae. ... isolated, viable or fresh cultures. ... two minute rotation, a positive ...
Medicine Products: