Navigation Links
Skin Rash Actually Signifies Better Outcomes for Pancreatic and,Lung Cancer Patients

nt because of the rash, yet those are the ones who are most likely to benefit,” Wacker said. “This is a critical problem and rather than permanently discontinue treatment, patients should talk to their doctor about an effective and proactive strategy to manage the rash while continuing Tarceva therapy.”

According to the researchers, these rashes can be controlled with mild steroids or antibiotics, and in most cases, they will improve with treatment. They are believed to be due to an inflammatory response as a result of EGFR inhibition in skin tissue, Wacker said.

The analysis looked at two placebo-controlled, double-blind, randomized, Phase III clinical trials testing Tarceva in advanced non-small cell lung cancer and pancreatic cancer ? studies which led to approval of the agent for treating both cancers. Wacker and his team excluded patients who died in the first month after starting the study because they may not have had time to develop the rash or the rash may have been under-reported in these ill patients.

Of the 673 patients in the lung cancer study, called BR.21, and in the Tarceva-treated group, 81 percent developed a rash, the majority of which was grade 2 (The study graded rashes from 1, relatively mild, to 4, severe). The researchers found that the presence of any rash correlated with overall and progression-free survival and that these correlations increased with the grade of rash. Specifically, Tarceva-treated patients who did not develop a rash survived a median of 3.3 months, compared to 7.1 months for those with a grade 1 rash, and 11.1 months for patients with more severe, grade 2 rashes.

They also found, however, that 18 percent of patients treated with a placebo also developed a rash, and that overall survival in these patients was also significantly longer (a median of 8.2 months compared to 4.7 months), compared to placebo patients who didn’t develop a rash. “We d
'"/>




Page: 1 2 3 4

Related medicine technology :

1. New Advances in Gastric Diagnostics: Smaller is Better
2. New Study Suggests Better Patient Outcomes with CYPHER Sirolimus-Eluting Coronary Stent than with Taxus Stent in Real-World Clinical Settings
3. Cypher Sirolimus-Eluting Coronary Stent Had Similar Results to Bypass Surgery and Better Outcomes Than Bare Metal Stents in Subgroup Analysis of Diabetic Patients With Multivessel Coronary Disease
4. The Sturdier Sex?: Study by Pittsburgh Scientists Finds Female Stem Cells Work Better
5. Major Discovery Raises Prospect of Better Patient Care By Improving Platelet Life Span
6. MEDIA ADVISORY: Subsets of Landmark Diabetes Trials Investigating MacroVascular Outcomes Presented at the American Diabetes Association 67th Scientific Sessions
7. Taxus VI Clinical Trial Demonstrates Positive Long-Term Outcomes for Moderate-Release Paclitaxel-Eluting Stent at Four Years
8. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
9. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
10. Immunomedics Reports Initial Clinical Results With Hpam4 For Pancreatic Cancer Therapy
11. Clinical Trial Results Change Standard of Care for Pancreatic Cancer Patients, Future Therapies Discussed
Post Your Comments:
(Date:6/30/2015)... Calif. , June 30, 2015  Ardelyx, Inc. ... on cardio-renal, gastrointestinal and metabolic diseases, today announced that ... July 14, 2015, from 8:00 a.m.- 1:00 pm EDT ... The Ardelyx senior management team will present ... lead compound, tenapanor, which has completed Phase 2b clinical ...
(Date:6/30/2015)... , BERKELEY, Kalifornien, und KOPENHAGEN, Dänemark, ... Biologics, Inc. , ein Weltmarktführer der klinischen ... anderen therapeutischen Proteinen, gab heute bekannt, dass ... der Produktionskapazität den Ausbau der nordamerikanischen Produktionsanlage ... mit der Ergänzung  einer Einweg-Anlage Bioreactor 6Pack™ ...
(Date:6/30/2015)... , June 24, 2015 Research ... of the "Global Endoscopy Devices Market 2015-2019" ... global endoscopy devices market to grow at a ... The global endoscopy devices market can be segmented ... accessories, and services. The market can be further ...
Breaking Medicine Technology:Ardelyx to Host Inaugural R&D Investor Day in New York City on July 14, 2015 2CMC Biologics baut GMP-Produktionskapazität in den USA aus 2CMC Biologics baut GMP-Produktionskapazität in den USA aus 3Global Endoscopy Devices Market 2015-2019 - Key Players are Boston Scientific, Johnson and Johnson, Medtronic, Karl Storz & Olympus 2Global Endoscopy Devices Market 2015-2019 - Key Players are Boston Scientific, Johnson and Johnson, Medtronic, Karl Storz & Olympus 3
... (Nasdaq: ISIS ), the leader in antisense therapeutics, ... Stifel Nicolaus, Healthcare Conference 2011 on Thursday, September 08, 2011 ... Boston. A live audio webcast of the presentation ... the Company,s Web site, www.isispharm.com .  A replay of ...
... Sequenom, Inc. (NASDAQ: SQNM ), a life ... Company,s participation at the William Blair and Company 5th Annual ... Hotel in New York City on September 8, 2011. ... Research and Development, will present on Thursday, September 8, 2011 ...
Cached Medicine Technology:Sequenom Announces Participation at William Blair and Company 5th Annual Emerging Growth Stock Conference 2
(Date:6/30/2015)... ... June 30, 2015 , ... According to a recent report by the U.S. ... deaths more than tripled in the same period—leading a majority of law enforcement agencies ... , a leading Florida-based drug treatment facility, asserts that these heroin statistics point to ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... Broadway by ... which features multiple patient and family member testimonials. Medicare rated the care center as ... plans to use the video to give future patients a firsthand look at the ...
(Date:6/30/2015)... ... June 30, 2015 , ... From the moment a patient ... with the incredible care that they receive and the luxury in which they are ... now they are proud to offer the same experience, just better! , Their office ...
(Date:6/30/2015)... ... June 30, 2015 , ... MJH Associates ... HRA Healthcare Research & Analytics , a consultative healthcare market research practice that ... of businesses. HRA offers quantitative and qualitative, custom and multi-client primary market research ...
(Date:6/30/2015)... ... ... Independence Day weekend is more than just fireworks to celebrate America’s birthday, it’s ... National Hot Dog Month. Americans are expected to eat more than 150 million hot ... enough to stretch from Washington D.C. to Los Angeles more than five times. , ...
Breaking Medicine News(10 mins):Health News:Novus Medical Detox Center Urges Education and Action as New DEA Report Reveals Rising Heroin Use and Deaths 2Health News:Novus Medical Detox Center Urges Education and Action as New DEA Report Reveals Rising Heroin Use and Deaths 3Health News:Novus Medical Detox Center Urges Education and Action as New DEA Report Reveals Rising Heroin Use and Deaths 4Health News:Broadway by the Sea Video Promotes Top Quality Service 2Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 2Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 3Health News:NJ Top Dentist, Dr. Laurence C. Breiterman is Now Offering the WOW Factor at His Highly Regarded Dental Practice 4Health News:HRA Healthcare Research & Analytics Welcomes 'Creative Problem Solver' as New Executive Vice President 2Health News:HRA Healthcare Research & Analytics Welcomes 'Creative Problem Solver' as New Executive Vice President 3Health News:Biggest Hot Dog Weekend of the Year to Kick Off National Hot Dog Month 2
... WEDNESDAY, Jan. 19 (HealthDay News) -- Intensive care patients ... are resistant to many drugs may be more likely ... new study suggests. The findings highlight the need ... Infectious Diseases Society of America (IDSA) guidelines, said the ...
... WEDNESDAY, Jan. 19 (HealthDay News) -- Nearly 42 percent ... end-of-life care services -- such as massages or ... alternative service provider, according to the latest data. ... and Prevention,s National Center for Health Statistics, concerns what ...
... hemorrhagic fever in humans, has no known cure or vaccine. ... scientists has uncovered a family of small molecules which appear ... inhibit its entry into human cells. The results are ... and are now online. Previous studies have shown ...
... DNA determine the outcome and success in patients who ... complications? The National Heart, Blood and Lung Institute of ... million, four-year grant to Fred Hutchinson Cancer Research Center ... of the Hutchinson Center,s Clinical Research Division and medical ...
... bin Zayed Al Nahyan Charity Foundation is granting $150 ... Center to support genetic-analysis based research, diagnosis and treatment ... Nahyan, Deputy Prime Minister, Minister of Presidential Affairs and ... Chancellor of The University of Texas System, recently witnessed ...
... online, open access, primary research journal for authors in all ... itself, PRX will publish original, high quality, scientifically sound research ... global multidisciplinary readership. PRX will provide validation through prompt and ... with the strong reputation of the Physical Review ...
Cached Medicine News:Health News:Study Questions Safety of Pneumonia Treatment Guidelines 2Health News:Many U.S. Hospices Provide Alternative Therapies: Report 2Health News:Small molecules may prevent ebola infection 2Health News:Does our DNA determine how well we respond to stem-cell transplantation? 2Health News:Khalifa Foundation grants MD Anderson $150 million for cancer research 2Health News:American Physical Society announces Physical Review X 2
... If you prefer a standard ... the Volk Iridectomy Lens. Its ... view you're used to but ... Volk's exclusive Double Aspheric design ...
... 2.2 offers extremely high resolution treatment capability ... an exceptionally wide 78° field of view. ... critical evaluation of the optic nerve head ... of the macula and disc. Redesigned to ...
... for focal laser therapy and mid-to-far peripheral ... a realistic contour of the retinal concavity, ... entire posterior pole extending to the equator. ... dynamic movement on the globe, therefore increasing ...
... The Digital 1.0x Imaging Lens is optimized ... reduce glare and reflections during general diagnosis and ... view of the posterior pole and a sharper ... Digital 1.0 X Imaging Lens is also ideal ...
Medicine Products: