Navigation Links
Skin Rash Actually Signifies Better Outcomes for Pancreatic and,Lung Cancer Patients

PHILADELPHIA, July 3, 2007-- – The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug’s developer, OSI Pharmaceuticals, Inc. This is not the first time that rash has been associated with a survival advantage with EGFR inhibitors – a class of drugs which includes erlotinib, cetuximab, panitumumab and others designed to block overproduction of the epidermal growth factor receptor – but it is the most detailed analysis to date.

The study, published in the July 1 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, reports that for patients taking Tarceva who developed a moderate to severe rash, survival without progression of disease was 245 percent longer than in patients who had a mild rash or none at all. In fact, in the majority of cases, the more severe the rash, the longer a patient’s cancer was held in check, researchers found.

This rash, which often looks like acne, can be unpleasant enough for some people to consider discontinuing treatment, but “it is important for physicians and patients to understand that this a positive event because it means there is likely to be a better clinical outcome,” said the lead author, Bret Wacker, MS Director of Biostatistics at OSI Pharmaceuticals, Inc. “Further studies are needed to both identify patients most likely to develop rash and to determine if dose escalation to induce rash can improve efficacy.”

Although few patients dropped out of the large Phase III clinical trials testing Tarceva in advanced non-small cell lung cancer and pancreatic cancer due to the rash, Wacker said he fears those who are taking Tarceva outside of a clinical trial may be likely to stop treatment.

“Some patients are stopping treatme
'"/>




Page: 1 2 3 4

Related medicine technology :

1. New Advances in Gastric Diagnostics: Smaller is Better
2. New Study Suggests Better Patient Outcomes with CYPHER Sirolimus-Eluting Coronary Stent than with Taxus Stent in Real-World Clinical Settings
3. Cypher Sirolimus-Eluting Coronary Stent Had Similar Results to Bypass Surgery and Better Outcomes Than Bare Metal Stents in Subgroup Analysis of Diabetic Patients With Multivessel Coronary Disease
4. The Sturdier Sex?: Study by Pittsburgh Scientists Finds Female Stem Cells Work Better
5. Major Discovery Raises Prospect of Better Patient Care By Improving Platelet Life Span
6. MEDIA ADVISORY: Subsets of Landmark Diabetes Trials Investigating MacroVascular Outcomes Presented at the American Diabetes Association 67th Scientific Sessions
7. Taxus VI Clinical Trial Demonstrates Positive Long-Term Outcomes for Moderate-Release Paclitaxel-Eluting Stent at Four Years
8. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
9. Eurands Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show
10. Immunomedics Reports Initial Clinical Results With Hpam4 For Pancreatic Cancer Therapy
11. Clinical Trial Results Change Standard of Care for Pancreatic Cancer Patients, Future Therapies Discussed
Post Your Comments:
(Date:2/26/2015)... , February 26, 2015 ... Outlook 2015: First -In- Class Innovations and Cost ... for Large Cap Pharmaceutical Companies research report to ... According to this Global Pharma US & ... as productivity measurements, divestment of non-core assets result ...
(Date:2/26/2015)... , Feb. 26, 2015  Spring Bank ... therapeutics for the treatment of Hepatitis B virus ... closing of a $22 million financing. Funds from ... 9200, a novel, broad spectrum antiviral agent derived ... acid hybrid (SMNH) chemistry platform, into Phase II ...
(Date:2/26/2015)... 26, 2015 Integrity Applications, Inc. (OTCQB: IGAP) ... model DF-F, a noninvasive  device that tracks blood glucose ... Ph.D., will head its new scientific advisory board that ... field of Diabetes research, monitoring and treatment. ... Chief Executive Officer and Head, Business Development of Profil ...
Breaking Medicine Technology:Global Pharma U.S. and EU Outlook 2015 Market Research Report 2Global Pharma U.S. and EU Outlook 2015 Market Research Report 3Global Pharma U.S. and EU Outlook 2015 Market Research Report 4Spring Bank Pharmaceuticals Completes $22 Million Financing 2Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 2Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 3Integrity Applications Names Prof. Lutz Heinemann to Advisory Board 4
... , , ... Remedies announced today that its NutraRx brand of natural ... country to receive the Emerson EQP Seal in recognition of the ... "After a rigorous evaluation by Emerson Ecologics of our NutraRx brand ...
... ALBUQUERQUE, N.M. , Feb. 16 ... develops and markets proprietary genomic tests, today announced an ... promote its diagnostic services to gastroenterologists throughout the ... gastroenterology-focused sales force will introduce Exagen,s proprietary gene expression ...
Cached Medicine Technology:Native Remedies' NutraRx Brand of Natural Products for Medical Practitioners Among First to Earn Prestigious 'Emerson EQP Seal' 2Native Remedies' NutraRx Brand of Natural Products for Medical Practitioners Among First to Earn Prestigious 'Emerson EQP Seal' 3Exagen Diagnostics Enters Into Exclusive Agreement With EndoChoice 2
(Date:2/27/2015)... York, NY (PRWEB) February 27, 2015 Ticket ... across North America during the summer months of 2015. ... are expected to sell out at a record pace. ... Sheeran Tickets, Austin, TX Frank Erwin Center, Wednesday, May 6, ... Theatre at Grand Prairie, Thursday, May 7, 2015 , 5/9/15, ...
(Date:2/27/2015)... Washington (PRWEB) February 27, 2015 ... North American Health Care, Inc. with the ... for performance in four key areas: Outstanding quality of ... involvement. , Administrator Lynda Baldwin was invited to attend ... February 3, 2015. “I am delighted to receive this ...
(Date:2/27/2015)... 2015 RDI-Engineering will be hosting an ... event on March 14, at Moreno Valley College. The ... how to use engineering software and tools, and a ... by Moreno Valley College’s Upward Bound Math and Science ... in hopes to encourage students to seek educational and ...
(Date:2/27/2015)... Leading massage chair retailer Emassagechair.com is known ... month they take a look at leading issues and help ... In the month of March they will be recognizing National ... by bringing awareness to the time change that occurs as ... start on March 2nd, and last until March 8th when ...
(Date:2/27/2015)... NewYork (PRWEB) February 27, 2015 ... study that presents the analysis of the cell ... The research report discusses the current scenario and ... surface coating industry for the period of 2015 ... @ http://www.researchmoz.us/global-cell-culture-protein-surface-coating-market-2015-2019-report.html , The research report, ...
Breaking Medicine News(10 mins):Health News:Ed Sheeran Tickets at the Hollywood Bowl, Verizon Theatre, The Mann Center, Darlings Waterfront Pavilion, Moda Center, BOK Center, Consol Energy & Red Rocks Now On Sale 2Health News:Ed Sheeran Tickets at the Hollywood Bowl, Verizon Theatre, The Mann Center, Darlings Waterfront Pavilion, Moda Center, BOK Center, Consol Energy & Red Rocks Now On Sale 3Health News:Ed Sheeran Tickets at the Hollywood Bowl, Verizon Theatre, The Mann Center, Darlings Waterfront Pavilion, Moda Center, BOK Center, Consol Energy & Red Rocks Now On Sale 4Health News:Burien Nursing and Rehabilitation Center Receives Top Honors with Facility of the Year Award 2Health News:Burien Nursing and Rehabilitation Center Receives Top Honors with Facility of the Year Award 3Health News:RDI-Engineering Participates in STEM”U”LATE Your Mind Event to Host Educational Exhibition 2Health News:Emassagechair Wants Shoppers to Think About the Benefits of Massage During National Sleep Awareness Week 2Health News:Emassagechair Wants Shoppers to Think About the Benefits of Massage During National Sleep Awareness Week 3Health News:Global Cell Culture Protein Surface Coating Industry: Rising Focus towards Stem Cells Research to Trigger Market Growth 2Health News:Global Cell Culture Protein Surface Coating Industry: Rising Focus towards Stem Cells Research to Trigger Market Growth 3
... the information furnished by Indira Gandhi National Open University ... Parliament/State legislature// or deemed to be university can offer ... and guidelines laid down by the Distance Education Council ... held on March 23, 2007 had resolved that it ...
... that the malfunction of a gene causes schizophrenia and ... the journal Neuron. ,The researchers said their findings ... treatments for schizophrenia and depression, which have been proven ... ,In their experiments, the researchers sought to explore ...
... has bagged this year's Ellis Island Medal of Honor, established ... US//. ,Jacob Eapen, who will receive the award ... going to be a boost for all my future endeavours," ... Ellis Island Medals of Honor are presented annually to US ...
... the functioning of maternity units in UK is an eye-opener ... in the hospitals. In a sting operation conducted by BBC, ... alarming practices. ,Some of the maternity units were ... midwives were overburdened with work. The midwife in charge at ...
... gays prefer to find out whether their partner’s HIV Status. ... to prevent// catching the disease. The risky behavior of unprotected ... is on the rise. ,In Britain, more than ... they continue to have unprotected sex. The saliva test also ...
... acids help new moms fight depression, according to a new ... ,"Depression in new mothers is common in ... of postpartum women. In some high-risk populations, the percentage can ... Since depression has devastating effects on both mother and baby, ...
Cached Medicine News:Health News:Malfunction of Gene Causes Schizophrenia, Depression 2Health News:United Kingdom: Maternity Units Exposed! Leaves Much to Be Desired 2Health News:Unprotected Sex Among the Gays on the Rise 2Health News:Breastfeeding and Omega-3 Fatty Acids Help New Moms Fight Depression 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: