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Sirion Therapeutics Announces Clinical Data to be Presented at the,2007 Association for Research in Vision and Ophthalmology (ARVO),Annual Meeting

or Uveitis Session Date: Wednesday, May 9, 2007, 8:30 a.m. - 10:15 a.m. Posterboard Number: B809, Program Number: 3905 Efficacy and Safety Results of a Phase III Study of Difluprednate Ophthalmic Emulsion 0.05% in Postoperative Inflammation Session Date: Wednesday, May 9, 2007, 8:30 a.m. - 10:15 a.m. Posterboard Number: B807 , Program Number: 3903 ARVO poster presentations featuring ST-602 (fenretinide): Reduction of Serum Retinol Binding Protein Arrests the Accumulation of Toxic Retinal Fluorophores: A Nonpharmacological Approach Session Date: Tuesday, May 8, 2007, 3:00 p.m. - 4:45 p.m. Posterboard Number: B220, Program Number: 3244 Megalin and Related Endocytic Receptors Mediate Uptake of Retinoid Binding Proteins in the Retinal Pigment Epithelium Session Date: Tuesday, May 8, 2007, 3:00 p.m. - 4:45 p.m. Posterboard Number: B221, Program Number: 3245 mleaper@siriontherapeutics.com

About Sirion Therapeutics, Inc.

Sirion Therapeutics is an ophthalmic biopharmaceutical company poised to compete in the $4 billion U.S. prescription ophthalmic market segment. Sirion is dedicated to the development and commercialization of innovative products to address unmet clinical needs. The company is currently developing a portfolio of product candidates that includes therapies in the areas of inflammatory diseases and conditions, allergy, dry eye, herpetic keratitis and dry age-related macular degeneration. Sirion is focused on growth through in- licensing, acquisition and geographic expansion. For more information regarding Sirion, please visit Sirion's website at http://www.siriontherapeutics.com.

CONTACT: Penny Cobb, of Sirion Therapeutics, Inc., +1-813-496-7325 x221, pcob
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