Navigation Links
Seroquel Sustained Release Schizophrenia Data Presented at ECP,Congress in Madrid

LONDON, March 18, 2007-AstraZeneca today announced clinical trial data for Seroquel sustained release formulation (quetiapine fumarate sustained release), at the European Congress of Psychiatry (ECP) in Madrid. The data demonstrated that the SEROQUEL® sustained release formulation (quetiapine fumarate sustained release), administered once daily, significantly improved symptoms associated with schizophrenia (measured by PANSS) and increased the time to psychiatric relapse, when administered through a three-step dose initiation aimed at reaching the effective dose range on the second day of treatment.

SEROQUEL® sustained release formulation is currently under review by regulatory authorities around the world for the treatment of schizophrenia and has not been approved in any market.

A randomised, double-blind study of 588 patients with acute schizophrenia (Study 132) compared SEROQUEL® sustained release formulation (400 mg/day, 600 mg/day or 800 mg/day) with placebo and found a significant improvement in Positive and Negative Syndrome Scale (PANSS) total scores from baseline for all doses. After six weeks’ treatment, reductions of 24.8 (p=0.03), 30.9 (p<0.001), and 31.3 (p<0.001) points were seen with 400, 600, and 800 mg doses, respectively, compared with a reduction of 18.8 points for placebo. Patients on SEROQUEL® sustained release formulation also had significantly better scores on the Clinical Global Impression (CGI)-Severity scale and significantly more patients showed improvement on the CGI-Improvement scale compared to placebo.

A second randomised, double-blind placebo controlled study (Study 004) examined time to first psychiatric relapse in 197 patients with clinically stable schizophrenia treated with either SEROQUEL® sustained release formulation (mean dose 669 mg/day) or placebo. Patients treated with SEROQUEL® sustained release formulation ex
'"/>




Page: 1 2 3 4

Related medicine technology :

1. New Study Analyses Confirm Once-Daily Seroquel XR Extended-Release Tablets as Effective Treatment for Schizophrenia
2. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
3. OREXIGEN Therapeutics Announces Sustained-Release Formulation of Zonisamide Shows Improved Tolerability When Compared to Immediate Release Formulation
4. Cervarix, the GSK Cervical Cancer Candidate Vaccine, Provides Sustained Immune Response in 100 Percent of Women up to 55 Years of Age
5. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
6. Medtronic Updates Long-Term ENDEAVOR I-II Clinical Data Showing Sustained Safety and Significant Reductions in Repeat Procedures
7. Copaxone Treatment over Two Years after Short Term Induction with Mitoxantrone Provided Sustained Benefits to Active Relapsing-Remitting Multiple Sclerosis Patients
8. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
9. Mayo Clinic News Release: Mayo Clinic-led Study Improves Breast Cancer Risk Prediction in Women with Atypia
10. Lupus Foundation of America Statement on Results for Clinical Study of CellCept Released by Aspreva Pharmaceutical Company
11. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
Post Your Comments:
(Date:5/22/2015)... SHENZHEN, China , May 22, 2015  China ... the "Company"), a leading retail drugstore chain in ... directly operated stores, today announced the resignation of Mr. ... Officer for personal reasons, effective immediately. Ms. Rebecca ... Officer by the Company,s board of directors, effective immediately. ...
(Date:5/21/2015)... Research and Markets ... of the "Arthroscopy Devices Markets Worldwide" ... http://photos.prnewswire.com/prnh/20130307/600769) , ,The purpose of this report ... market for Arthroscopy Devices. The report discusses ... market for these products. , ,Product - ...
(Date:5/21/2015)... , 21. Mai 2015 /PRNewswire/ ... DPRX ), ein Unternehmen für Arzneimittel ... die Entwicklung und Vermarktung von Locilex® ... kündigte heute eine wissenschaftliche Posterpräsentation an, ... des Unternehmens vorstellt, OneStep-1 und OneStep-2, ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 2China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 3Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 2Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 3Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 4Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 5Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 6Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 7
... RESTON, Virginia, August 25, 2011 ... Wi-Fi-based Real Time Location Systems (RTLS), ... been integrated into a healthcare telecommunications system developed ... will provide location tracking capabilities to HEALTHCAREwireless™, which ...
... Aug. 25, 2011 QRxPharma Limited (ASX: QRX and ... Application (NDA) clinical data package to the United States ... immediate-release Dual Opioid® pain therapy comprised of a patented ... NDA Chemistry, Manufacturing and Controls (CMC) module was submitted ...
Cached Medicine Technology:Ekahau Joins Forces with LPS Services to Deliver Location Tracking for HEALTHCAREwireless™ Solution 2Ekahau Joins Forces with LPS Services to Deliver Location Tracking for HEALTHCAREwireless™ Solution 3QRxPharma Completes NDA Submission for MoxDuo® IR 2QRxPharma Completes NDA Submission for MoxDuo® IR 3
(Date:5/24/2015)... The Rolling Stones Zip Code summer stadium ... Petco Park. This iconic group is ready for their ... had a warmup show in Los Angeles at the Henry ... this beloved band not only played their Sticky Fingers album ... "Jumping Jack Flash," "Moonlight Mile" and "All Down the ...
(Date:5/24/2015)... May 24, 2015 Scientists with Cardno ... on air quality compliance issues that may have raised ... Surviving Mesothelioma has just posted an article on the ... , The group found airborne asbestos levels well above ... between 1984 and 2011. , “Asbestos compliance sampling data ...
(Date:5/24/2015)... 24, 2015 Indiana Fiber Network, LLC ... Midwest Telecom of America, Inc. (MTA) has selected IFN ... Cory Childs, IFN Enterprise Sales Manager, fiber route diversity ... “IFN’s fiber transport provides MTA with the diverse fiber ... Tier 1 Internet and voice carriers located at Henry ...
(Date:5/23/2015)... City, FL (PRWEB) May 23, 2015 On ... to build a new playground for Branches Florida City exactly ... the former play space in 2010. , A large fire ... new playground on May 23, 2010 in the middle of ... watched. The fire was later declared arson even though it ...
(Date:5/23/2015)... York, NY (PRWEB) May 23, 2015 ... announced that, “the company has been the target ... as a part of the company’s ongoing Information Technology ... on health insurers.” , The most notable attack ... year when Anthem Inc., the nation’s second largest health ...
Breaking Medicine News(10 mins):Health News:The Rolling Stones Tickets in San Diego, Orlando, Minneapolis, Dallas, Pittsburgh, Indianapolis, Atlanta, Detroit, Milwaukee, Kansas City, Columbus, Nashville & Raleigh 2Health News:New Analysis Finds Too Many Employers Ignored OSHA Asbestos Guidelines, According to Surviving Mesothelioma 2Health News:Indiana Fiber Network, LLC Enables Midwest Telecom of America with Fiber Route Diversity 2Health News:Five Years After Fire, Branches Rebuilds Playground 2Health News:One Headline Making Cyber Attack Sparks Discovery of Another 2Health News:One Headline Making Cyber Attack Sparks Discovery of Another 3Health News:One Headline Making Cyber Attack Sparks Discovery of Another 4
... leading spinal surgeons who was keenly interested in Buddhism and traveled ... died at the age// of 93. ,Born in 1913, ... to Winchester College at the age of 13 and received a ... and biochemistry. ,In 1934 Roaf's parents moved from London ...
... for the treatment of their thalassaemic daughter are drying up. ... to spread awareness about the disease.// ,Meet Samir ... the knot, they didn't know how thalassaemia could affect their ... a premarital blood detection test and initiated an awareness campaign ...
... in animal evolution has puzzled scientists for centuries. Vertebrates, ... their CNSs are different and were thought to have ... Researchers from the European Molecular Biology Laboratory [EMBL] in ... probably much older than expected. The study, which is ...
... to pull up its socks on health issues, lest it ... of chronic diseases’. If the present trend continues//, 66% of ... ,A study conducted by Assocham and Price Waterhouse ... shown the vulnerability of the Indian population to cardiovascular disease. ...
... motivating seniors and others with Medicare to make the most ... Department of Health and Human Services (HHS) and the Centers ... A Healthier US Starts Here. , ... the Medicare Prevention tour bus will visit each of the ...
... Administration (FDA) is alerting health care professionals and consumers ... drug safety information. The broadcasts, commonly known as podcasts, ... players. ,The service is part of the ... concerning the safety of marketed medications when unexpected ...
Cached Medicine News:Health News:Thalassaemic Child's Parents Campaign for Awareness 2Health News:The Origin of the Brain Lies in a Worm 2Health News:Seniors Encouraged To Make Use Of Medicare’s Freebie 2Health News:FDA Announces Audio Broadcasts on Emerging Drug Safety Information 2