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Separate Sets of Research Show Treatment Improved Quality of Life,,,in as Early as Three Weeks; Patient Adherence to Medication is,,,Multifactorial

WASHINGTON, May 22, 2007 /PRNewswire/ -- Results from analyses looking at factors contributing to successful treatment of ulcerative colitis (UC), were presented at Digestive Disease Week (DDW) this week. Both of these studies were funded by Procter & Gamble (P&G) Pharmaceuticals, Inc. Findings from one study offer new information on improvement of quality of life for UC patients treated with Asacol(R) (mesalamine), which is from a class of agents known as 5-ASAs. A separate study looked to pinpoint factors that contributed to non- adherence to medication in patients treated with agents from the 5-ASA class.

"Everyday, UC patients fight to stay on top of their disease. They want to be able to function as close to normal for them as possible. These results should help emphasize to physicians how effective treatment can improve quality of life." said Michel Farhat, PhD, GI Professional & Scientific Relations, P&G Pharmaceuticals. "Additionally, there may not be just one reason why patients have trouble adhering to their medication, and physicians and patients need to examine all potential factors before choosing a treatment."

Asacol Improved Quality of Life in UC Patients in as Early as Three Weeks

The abstract, "Delayed-release mesalamine significantly improved quality of life (QoL) in Patients with Mildly and Moderately Active Ulcerative Colitis (UC)," evaluated QoL in 687 patients with mildly or moderately active UC in patients treated for six weeks with delayed-release mesalamine Asacol 2.4g (marketed 400mg tablet) daily or 4.8g daily (investigational 800mg mesalamine tablet). Data from two multicenter, randomized, double-blind, active- controlled trials were combined and analyzed, and found that patients achieved overall improvement in QoL in as early as three weeks from the start of treatment.

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