Navigation Links
Scottish Scientists Test ‘Secret Weapon’ Against,Tumours

LONDON, March 8, 2007--Cancer Research UK scientists in Glasgow have devised a new method of attacking cancer cells. They report the findings in the Journal of Clinical Investigation* today (Thursday).

A team of scientists from the Beatson Institute for Cancer Research gave mice a chemical that caused cancer cells to commit suicide, significantly slowing the growth of the tumours they were carrying. The chemical kick started a gene called p73 that brings about cancer cell death.

This early research could pave the way for a new agent to stop tumours growing. The researchers suggest that sending the protein – called 37AA – directly into the bloodstream using a ‘nanoparticle’ delivery system could be a potential way to find and kill tumour cells that have spread as well as those in the primary tumour.

In further laboratory studies the research team found that the chemical could kill several types of cancer cells – including bowel, cervical and bone cells.

Lead researcher Dr Kevin Ryan, a Cancer Research UK senior research fellow and head of the Tumour Cell Death Laboratory at the Beatson Institute, said: “Our study has shown for the first time that the selective activation of a gene called p73 can cause cell death in tumours. We think this approach has the potential to be developed into an effective treatment for cancer.”

The gene p73 is related to p53 – one of the most important genes known to protect against the development of cancer. p53, known as the ‘guardian of the genome’, was first identified by Cancer Research UK scientists in London.

p53 is damaged in the vast majority of cancers so scientists across the globe are looking for ways to restore the gene as a way of treating the disease. However, in some cancers, p53 is damaged in such a way that its function cannot be restored. p73 is a promising alternativ
'"/>




Page: 1 2 3

Related medicine technology :

1. Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression
2. Schepens Scientists Identify Key to Integrating Transplanted Nerve Cells Into Injured Tissue
3. Karmanos Physician-Scientists Examine Racial Disparities in Patients with Gynecologic Cancer
4. Scientists Implicate Gene in Vitiligo and Other Autoimmune Diseases
5. The Sturdier Sex?: Study by Pittsburgh Scientists Finds Female Stem Cells Work Better
6. Alnylam and Stanford University Scientists Discover New Role for microRNAs (miRNAs) in T Cell Biology and Immunity
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scottish Scientists Test Secret Weapon Against Tumours
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness & ... Center by the Medical Fitness Association, a non-profit organization ... their full potential. The Cadence Fitness & Health Center ... suburbs and second in the Chicagoland area. ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Insulin Pump ... http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining strong acceptance ...
(Date:1/15/2014)... LAVAL, Quebec , Jan. 15, 2014  Valeant Pharmaceuticals ... VRX) announced that the applicable waiting period under the ... to the previously announced tender offer by its indirect ... the outstanding shares of common stock of Solta Medical, ...
Breaking Medicine Technology:Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
(Date:4/17/2014)... chronic inflammation in non-cancerous prostate tissue may have nearly ... those with no inflammation, according to results of a ... Kimmel Cancer Center. , The link between persistent inflammation ... high-grade prostate cancer those with a Gleason score ... the most aggressive and rapidly growing prostate cancers. , ...
(Date:4/17/2014)... have identified new pain relief targets that could ... BBSRC-funded researchers at King,s College London made the ... in the periphery of the body. , Dr ... identifying mechanisms underlying pain generation and our findings ... side effects." , One potential side effect of ...
(Date:4/17/2014)... PLOS Pathogens , children who live in regions ... an immune response to infection with malaria parasites that ... fever and illness and partially control the growth of ... researchers develop future interventions that prevent or mitigate the ... approximately 200 million cases of malaria occur worldwide, resulting ...
(Date:4/17/2014)... Diego School of Medicine report that older women, plucky ... loss are more likely to be compassionate toward strangers ... in this month,s issue of the International Journal ... associated with better health and well-being as we age, ... the outcomes of individuals whose deficits in compassion put ...
(Date:4/17/2014)... in the April issue of Immunity , Kevin ... Medical Research, says it,s time to take a fresh ... sepsis, which kills millions worldwide every year, including ... released into the bloodstream to fight an injury or ... for maintaining good health without inflammation, wounds and ...
Breaking Medicine News(10 mins):Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:New pain relief targets discovered 2Health News:Study sheds light on how the immune system protects children from malaria 2Health News:The ilk of human kindness 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2
... and performance services, recently supported Global Medical Brigades on a medical ... ... IL (PRWeb) May 1, 2009-- AthletiCo , an Illinois-based leader ... Brigades on a medical mission trip to Honduras. Global ...
... Health care professionals in every specialty can earn additional ... lawsuits, but they must learn how to be effective ... developed by board-certified physician and medical expert allows them ... own timelines and from the comfort of their own ...
... study in the May 1 issue of the journal ... consistent bedtime routine contributes to improvements in multiple aspects ... mood. , Results indicate that the establishment of a ... behaviors for infants and toddlers. Improvements were seen in ...
... 30 Senate President pro Tem Darrell Steinberg ... Select Committee on Autism (ASD) & Related Disorders ... important contributions of the three-year California ... which was Chaired by Steinberg and ended in ...
... 30 The former director of information technology for ... a guilty plea to intruding into her former employer,s ... Lanny A. Breuer, acting U.S. Attorney Tim Johnson and ... today.At a hearing before U.S. District Judge David Hittner, ...
... Scholarly Journals, Web of Science Can Identify Highly Valuable ... in the Face of the Current Swine Flu OutbreakPHILADELPHIA ... of Science is the world,s leading ... and 130,000 academic conferences from around the globe in ...
Cached Medicine News:Health News:AthletiCo Employees Volunteer Time And Talent To Support Global Medical Brigades 2Health News:AthletiCo Employees Volunteer Time And Talent To Support Global Medical Brigades 3Health News:Home Study Course Teaches Health Care Professionals How to be Effective Experts & Defendants in Medical Malpractice Lawsuits 2Health News:Home Study Course Teaches Health Care Professionals How to be Effective Experts & Defendants in Medical Malpractice Lawsuits 3Health News:Institution of a bedtime routine improves sleep in infants and toddlers, maternal mood 2Health News:Institution of a bedtime routine improves sleep in infants and toddlers, maternal mood 3Health News:Steinberg Announces Senate Select Committee on Autism and Related Disorders 2Health News:Computer Administrator Pleads Guilty to Hacking Former Employer's Computer System 2Health News:Thomson Reuters Web of Science(R) Provides Insights Into More than a Century of Influenza Research for Today's Health Professionals 2Health News:Thomson Reuters Web of Science(R) Provides Insights Into More than a Century of Influenza Research for Today's Health Professionals 3Health News:Thomson Reuters Web of Science(R) Provides Insights Into More than a Century of Influenza Research for Today's Health Professionals 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: