Navigation Links
Sangamo BioSciences Announces Presentation of ZFP Therapeutic Data,From Nerve Regeneration Program at American Society for Neural,Therapy and Repair Meeting

d measurable VEGF ZFP TF and increased levels of all of the major isoforms of the VEGF protein. They observed a corresponding neuroprotective effect with a statistically significant decrease in nerve fiber degradation and post-injury nerve cell death. They also noted an increase in blood vessel density around the injury. Most importantly, in a severe model of SCI where animals are paraplegic post- injury, they observed a statistically significant (p<0.0001) improvement of hind-limb function over time.

"I am very impressed by the improvements that we were able to generate through treatment of acutely injured spinal cord with the VEGF ZFP TF," stated Dr. Fehlings. "In earlier studies we had observed clear increases in VEGF protein levels and good evidence of a neuroprotective effect of the ZFP TF. In these more recent experiments we have seen evidence of improved functional outcomes that are quite impressive compared with any other therapeutic approach that we have evaluated including stem cell therapies. We look forward to continuing these studies in collaboration with Sangamo and believe that this VEGF-activating ZFP TF may hold promise as a unique therapy for spinal cord injury and other forms of neural injury."

"Dr. Fehling's studies, particularly the experiments that demonstrate an improvement in hind-limb function, are very encouraging," said Dale Ando, M.D. Sangamo's vice president of therapeutic development and chief medical officer. "The outcomes of these studies are consistent with other data from a variety of models that suggest that our ZFP TF activator of VEGF expression has regenerative effects on nerves and a positive effect on the health of nerves injured by both mechanical means such as in spinal cord injury and the toxicity that is a function of diabetes. We are very pleased to continue to work with Dr Fehlings who is world-renown for his work on SCI and has significant clinical trial experience in this area."

S. Kaye Spratt, Ph.
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Sangamo BioSciences Announces Presentation of Phase 1 ZFP Therapeutic Data at American Diabetes Association Meeting
2. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
3. YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy
4. IR BioSciences Announces Promising Data from Study of Its Compound Homspera
5. YM BioSciences Reports AeroLEF Randomized Phase IIb Trial Meets Primary Endpoint in Patients with Post-Surgical Pain
6. ImmuneRegen BioSciences Announces Promising Data on Homspera Suggesting Potential as a Co-Therapeutic Agent
7. Study in Cell by Magen BioSciences Co-Founder David E. Fisher Identifies New Roles in Skin Cancer Prevention for Key Tumor Suppressor Protein
8. IR BioSciences Announces Data Demonstrating Radilex Stimulation of Stem Cells Results in Hematopoietic Recovery Following Lethal Irradiation
9. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
10. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
Post Your Comments:
(Date:5/4/2015)... , May 4, 2015 RadiologyAuction will have their ... video and product demonstrations at the end of the ... such as Kodak and Fuji Cr,s, Agfa and Sony, ... the first event. Various imaging equipment will be available ... After years of buying and selling imaging ...
(Date:5/4/2015)... , May 4, 2015  Oncobiologics, Inc., a ... antibody (mAb) biosimilars, has completed the construction of ... headquarters in Cranbury, New Jersey ... facility is designed to utilize multiple technologies ... commercial scale.  Through the use of the latest ...
(Date:5/4/2015)... CARLSBAD, Calif. , May 4, 2015  Isis ... an exclusive license agreement with Bayer HealthCare (Bayer) to ... of thrombosis. Under the terms of the agreement, Isis ... near-term payments, including an immediate $100 million up-front payment ... program following a Phase 2 study in patients with ...
Breaking Medicine Technology:RadiologyAuction Announces Event Starting On May 5th 2Oncobiologics opens commercial launch manufacturing facility in Cranbury, New Jersey 2Oncobiologics opens commercial launch manufacturing facility in Cranbury, New Jersey 3Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 2Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 3Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 4Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 5
... , NEW YORK, Nov. 19 As ... is here. Here,s more on preparing yourself. , Listen to ... http://inr.mediaseed.tv/oneClip_C/?feed=ksLp_frMYEE7RzdnRfCsbxc9R2VXAOIF , Medialink is a division ... text, graphics and photos at http://www.thenewsmarket.com . ...
... , , NEWPORT NEWS, Va., Nov. 19 ... recognized and endorsed by two highly esteemed organizations for ... Imaging (SBI) and the American College of Surgeons. Both ... breakthrough imaging technology for the early detection of breast ...
Cached Medicine Technology:Esteemed Endorsements Recognize Promising Future of Breast-Specific Gamma Imaging (BSGI) 2Esteemed Endorsements Recognize Promising Future of Breast-Specific Gamma Imaging (BSGI) 3
(Date:5/4/2015)... 04, 2015 Dr. Richard Champagne, DMD, ... chosen to receive the America’s Best Dentist Award, given ... selection as a top dentist is a reflection of ... education and his compassion for his patients. , Each ... exemplify excellence in their field. These nominees are dentists ...
(Date:5/4/2015)... Sylvia Hawthorn-Deppen shared her experiences living with ... others in similar situations that they were not alone, in ... Discovery of New Energy” (published by Balboa Press). This year ... renewed press campaign. , “I have spent nearly 60 years ... says. “As an adolescent I got into trouble with an ...
(Date:5/4/2015)... Vista, California (PRWEB) May 04, 2015 ... introduced a brand new lubricant -- Astroglide TTC™ ... impede sperm motility and alter pH levels, Astroglide TTC™ ... conception. , According to the Centers for Disease ... have trouble getting pregnant or sustaining a pregnancy, ...
(Date:5/4/2015)... 04, 2015 “ Food Cost Calculator ” ... which takes a look at the latest and coolest applications ... the host of AppWatch and technology expert, conducted the app ... owners to manage and efficiently calculate food costs. , The ... In fact, the industry has an estimated 1.8 trillion dollar ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 ... just released the first-ever congenital heart disease ... Catheterization Laboratory (PCCL) accreditation. Driven by the ... are a comprehensive review of interventional procedures ... heart disease. , “The ACE CHD Standards ...
Breaking Medicine News(10 mins):Health News:New Jersey Dentist Dr. Richard Champagne Nominated for America’s Best Dentist Award 2Health News:Author launches new press campaign for 2012 book ‘Wheel’ 2Health News:Astroglide Announces the Birth of Its New Baby: Astroglide TTC 2Health News:Astroglide Announces the Birth of Its New Baby: Astroglide TTC 3Health News:An Application to Manage a Successful Restaurant Was Featured on NewsWatch Television 2Health News:Accreditation for Cardiovascular Excellence (ACE) Publishes New Standards for Pediatric and Adult Congenital Cardiac Catheterization Laboratories 2
... CLEVELAND, Feb. 4 Franklin & Seidelmann,( ... market penetration into the hospital sector with the,addition of ... , , -- Barnes-Kasson Hospital, Susquehanna, ... Owenton, KY, -- Syringa General Hospital, ...
... Kensey Nash Corporation (Nasdaq: KNSY ), a leading ... a wide range of medical procedures, today announced the resignation ... Ramius LLC, from its Board of Directors.Mr. Smith became a ... member of the Corporate Governance and Nominating Committee as well ...
... counterfeit and adulterated medicines posing an increasing risk to ... Pharmacopeial (USP) Convention today announces new standards for two ... episodes of adulteration resulting in patient deaths. , ... heparin and the sweetener glycerin, comes on the heels ...
... Impacts One in Four Americans Show Features Real People with ... Bob Schieffer and Denver Broncos, Quarterback Jay CutlerWESTPORT, Conn., Feb. ... today the new 2009 television schedule for dLifeTV ... people living with diabetes, airing every Sunday on CNBC at ...
... U.S. Preventive Medicine(R), the leader in disease prevention ... Christopher Fey, Chairman and CEO, and Fred Goldstein, President ... Services Conference, to be held February 9-11 in New ... U.S. Preventive Medicine will participate in this exclusive conference ...
... and special product offerings available in store during ... CVS/pharmacy, America,s largest retail pharmacy, will mark American ... about maintaining heart health and preventing heart disease. ... month on many heart health-related products.Heart disease is ...
Cached Medicine News:Health News:Franklin & Seidelmann Expands into Critical Access Hospital Market Provides 24 x 7 Teleradiology Service for Three New Clients 2Health News:Franklin & Seidelmann Expands into Critical Access Hospital Market Provides 24 x 7 Teleradiology Service for Three New Clients 3Health News:Kensey Nash Announces Director Resignation 2Health News:USP announces new standards to protect patients from counterfeit and adulterated medicines 2Health News:dLifeTV Announces New Season Programming and Celebrity Guests; Only Nationally-Broadcast Program About Diabetes Celebrates 5th Year and 200th Show 2Health News:dLifeTV Announces New Season Programming and Celebrity Guests; Only Nationally-Broadcast Program About Diabetes Celebrates 5th Year and 200th Show 3Health News:U.S. Preventive Medicine(R) Executives to Present at 2009 UBS Global Healthcare Services Conference 2Health News:CVS/pharmacy Taking Health to Heart in February 2Health News:CVS/pharmacy Taking Health to Heart in February 3
The New Vantage Plus. The PLUS gives you: ,P Premium intelligent optics ,L Lighter weight and brighter images ,U Unique wireless patented technology ,S Smaller and more compact size ...
STAT-CRIT is a rapid, one-step system for measuring hematocrit....
... Simple, compact, and easy to use, ... surgery technology to every OR. The business ... provide hospitals and surgeons with the most ... their facilities. ,The z-boxTM is designed to ...
...
Medicine Products: