o BioSciences, Inc. is focused on the research and
development of novel DNA-binding proteins for therapeutic gene
regulation and modification. The most advanced ZFP Therapeutic(TM)
development program is currently in Phase 2 clinical trials for
evaluation of safety and clinical effect in patients with diabetic
neuropathy. Phase 1 clinical trials are ongoing to evaluate a ZFP
Therapeutic for peripheral artery disease. Other therapeutic
development programs are focused on cancer and HIV/AIDS,
neuropathic pain, nerve regeneration, ischemic heart disease and
monogenic diseases. Sangamo's core competencies enable the
engineering of a class of DNA-binding proteins known as zinc finger
DNA-binding proteins (ZFPs). By engineering ZFPs that recognize a
specific DNA sequence Sangamo has created ZFP transcription factors
(ZFP TF(TM)) that can control gene expression and, consequently,
cell function. Sangamo is also developing sequence-specific ZFP
Nucleases (ZFN(TM)) for therapeutic gene modification as a
treatment for a variety of monogenic diseases, such as X-linked
SCID and hemophilia, and for infectious diseases, such as HIV.
Sangamo has established several Enabling Technology Agreements with
companies to apply its ZFP Technology to enhance the production of
protein pharmaceuticals. For more information about Sangamo, visit
the company's web site at
http://www.sangamo.com.
This press release may contain forward-looking statements based
on Sangamo's current expectations. These forward-looking statements
include, without limitation, references to the clinical trials of
SB-509, research and development of novel ZFP TFs and ZFNs and
therapeutic applications of Sangamo's ZFP technology platform.
Actual results may differ materially from these forward-looking
statements due to a number of factors, including uncertainties
relating to the initiation and completion of stages of the SB- 509
clinical trials, whether the SB
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Page: 1 2 3 4 5 6 7 8 9 Related medicine technology :1.
Sangamo BioSciences Announces Presentation of ZFP Therapeutic Data
From Nerve Regeneration Program at American Society for Neural
Therapy and Repair Meeting2.
YM BioSciences Announces Secondary Efficacy and Safety Findings in
Randomized Phase IIB Aerolef Trial3.
YM BioSciences Announces Preclinical Data Confirming Nimotuzumab
Binds to the EGF Receptor and Potentiates Radiotherapy4.
IR BioSciences Announces Promising Data from Study of Its Compound
Homspera5.
YM BioSciences Reports AeroLEF Randomized Phase IIb Trial Meets
Primary Endpoint in Patients with Post-Surgical Pain6.
ImmuneRegen BioSciences Announces Promising Data on Homspera
Suggesting Potential as a Co-Therapeutic Agent7.
Study in Cell by Magen BioSciences Co-Founder David E. Fisher
Identifies New Roles in Skin Cancer Prevention for Key Tumor
Suppressor Protein8.
IR BioSciences Announces Data Demonstrating Radilex Stimulation of
Stem Cells Results in Hematopoietic Recovery Following Lethal
Irradiation9.
Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial10.
Neose Announces Presentation of Positive Preclinical Data on
GlycoPEGylated Factor VIIa at the XXI Congress of the International
Society on Thrombosis and Haemostasis11.
Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy
of BF-200 ALA In Actinic Keratosis