Navigation Links
Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well,Tolerated in Phase 3 Study

Patients Using ROX-888 Required Significantly Less Morphine After Major Abdominal Surgery Company On Track To File NDA In 2008

MENLO PARK, CA (June 6, 2007) – ROXRO PHARMA Inc. said today that ROX-888, its novel intranasal analgesic, rapidly and effectively eased pain and was well tolerated by patients who had undergone major abdominal surgery in a Phase 3 clinical study.

"This completes our second and final Phase 3 clinical study," said ROXRO PHARMA’s Chief Scientific Officer Roger Whiting. The company intends to include fully analyzed data in its New Drug Application for submission to the U.S. Food and Drug Administration. "We are very pleased with the solid results of this Phase 3 study and are on track to file our NDA in the first half of 2008," Whiting said.

In the Phase 3 study, patients who received ROX-888 reported greater improvement in pain relief and required 22 percent less morphine in the first 24 hours following surgery compared to patients who had access to morphine alone. ROX-888 is an intranasal formulation of ketorolac, a non-steroidal anti-inflammatory medicine most often administered as an intramuscular injection or intravenously for the short-term treatment of moderately severe pain. "ROX-888 is an important breakthrough in treating pain," said Dr. Neil Singla, Director of Clinical Research at Huntington Memorial Hospital in Los Angeles. "It is rapidly absorbed into the bloodstream, and relieves pain as fast as an intramuscular injection. There is a need for new analgesics like ROX-888 that do not have the troublesome side effects and abuse risks associated with narcotic pain relievers." The Phase 3 double-blind, placebo-controlled study included 321 patients who had undergone major abdominal surgery. Patients were randomized to receive either intranasal ketorolac (30 mg) or placebo. All study participants had access to patient-controlled morphine. "Pain is at its greatest intensity in the first 24
'"/>




Page: 1 2

Related medicine technology :

1. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
2. Anacor Identifies a Novel Mechanism for Its Lead Anti-Fungal Drug, AN2690; Findings Published in Science
3. Novelos Therapeutics Announces Encouraging Results in Ongoing Phase 2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care
4. Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective Small Molecule Anti-Tumor Agent With Novel Mechanism of Action
5. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
6. Novel Mechanism Insights and Additional Data on CombinatoRx Drug Candidates to Be Presented at Upcoming EULAR Meeting
7. Anacor Clinical Study of AN2728, a Novel Anti-Inflammatory Compound, Shows Efficacy in Psoriasis
8. Metabasis Therapeutics Presents Results of Preclinical Studies for MB07811, Its Novel Product Candidate for the Treatment of Hyperlipidemia, at the Endocrine Societys Annual Meeting
9. Encouraging Clinical Activity of GSKs Novel Cancer Immunotherapeutic Confirmed in Phase II Study in Patients with Most Common Form of Lung Cancer
10. Clinical Data on ARIADs Novel mTOR Inhibitor, AP23573, To Be Presented at the ASCO Annual Meeting
11. VGX Pharmaceuticals Novel HIV and Pandemic Influenza DNA Vaccine Candidates Trigger Robust Immune Responses and Protection in Pre-Clinical Models
Post Your Comments:
(Date:8/20/2014)... Research and Markets  has announced the addition of the ... Global Market Report of Pralmorelin (CAS 158861-67-7) ... ( Europe , Asia , ... etc.). It captures Pralmorelin market trends, pays close ... primary areas; manufacture methods & technology development, market situation & ...
(Date:8/20/2014)... Reportlinker.com announces that a new market ... Global Coatings for Medical Devices Industry ... This report analyzes the worldwide markets for Coatings ... following Product Segments: Active Coatings, Protective Coatings, Optical ... comprehensive analytics for the US, Canada ...
(Date:8/20/2014)... SALT LAKE CITY , Aug. 20, 2014 /PRNewswire/ ... their revolutionary mobile diagnostic platform during a special event ... City, Utah , on September 5, 2014. The ... be LiveStreamed on the ApolloDx website, www.apollodx.com .  ... will transform diagnostic testing," said Jared Bauer , ...
Breaking Medicine Technology:Global Market Report of Pralmorelin 2Global Coatings for Medical Devices Industry 2Global Coatings for Medical Devices Industry 3Global Coatings for Medical Devices Industry 4Global Coatings for Medical Devices Industry 5Global Coatings for Medical Devices Industry 6Global Coatings for Medical Devices Industry 7Global Coatings for Medical Devices Industry 8Global Coatings for Medical Devices Industry 9Global Coatings for Medical Devices Industry 10Global Coatings for Medical Devices Industry 11Global Coatings for Medical Devices Industry 12Global Coatings for Medical Devices Industry 13Global Coatings for Medical Devices Industry 14Global Coatings for Medical Devices Industry 15Global Coatings for Medical Devices Industry 16Global Coatings for Medical Devices Industry 17Global Coatings for Medical Devices Industry 18Global Coatings for Medical Devices Industry 19Global Coatings for Medical Devices Industry 20Global Coatings for Medical Devices Industry 21
... among most serious injuries to childrenLAS VEGAS, Feb. 25 ... joint infections, a hip problem known as slipped epiphysis, ... problems and other complications if children are not treated ... released today at the 2009 Annual Meeting of the ...
... Cincinnati Children,s Hospital Medical Center has received a ... Foundation to help prevent flu in pregnant women and ... Most childhood deaths occur in the first hours and ... infections. In developing countries, where many births happen ...
Cached Medicine Technology:Children and Orthopaedic Surgical Emergencies 2Children and Orthopaedic Surgical Emergencies 3Children's Hospital Receives $6.7 Million Grant From Gates Foundation to Study Influenza Vaccine in Pregnant Women in Asia 2
(Date:8/20/2014)... New York, NY (PRWEB) August 20, 2014 ... filed on behalf of women who were allegedly ... to move forward in New Jersey’s Bergen County Superior ... Management Order issued on August 15, 2014, the Court ... custodial files for Mirena lawsuits that are part of ...
(Date:8/20/2014)... HealthDay Reporter WEDNESDAY, Aug. ... colds, flu and other minor infections might trigger a strong ... a new study suggests. Just five out of 100,000 ... said Dr. Heather Fullerton, lead author of the study and ... California, San Francisco Benioff Children,s Hospital. "It seems infections play ...
(Date:8/20/2014)... Dennis Thompson HealthDay Reporter ... may help older women avoid a condition that causes a ... postmenopausal women had a 10 percent lower risk of developing ... report in the Aug. 20 issue of the Journal ... this protection against the heart rhythm disorder even if they ...
(Date:8/20/2014)... HealthDay Reporter WEDNESDAY, Aug. 20, ... long been an option, but a new study shows that ... most common reasons women didn,t undergo reconstruction was that they ... or they were focused on their cancer treatment," said lead ... Sloan Kettering Cancer Center, in New York City. Also ...
(Date:8/20/2014)... 2014 Park Cities Pet Sitter , ... 4 Pets supply donation drive that benefits the animal shelter ... campaign that coincides with the Humane Society of the United ... through 8th, 2014. , As part of their participation, Park ... monetary donations for the Presents 4 Pets drive from their ...
Breaking Medicine News(10 mins):Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 3Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 4Health News:Study Ties Colds, Flu to Rare Risk of Stroke in Kids 2Health News:Study Ties Colds, Flu to Rare Risk of Stroke in Kids 3Health News:Exercise May Guard Against Irregular Heartbeat in Older Women 2Health News:Exercise May Guard Against Irregular Heartbeat in Older Women 3Health News:Many Women Who Have Mastectomy Don't Get Breast Reconstruction: Study 2Health News:Many Women Who Have Mastectomy Don't Get Breast Reconstruction: Study 3Health News:Dallas-based Park Cities Pet Sitter Announces Participation in the 2014 National Association of Professional Pet Sitters “Presents 4 Pets” Program 2Health News:Dallas-based Park Cities Pet Sitter Announces Participation in the 2014 National Association of Professional Pet Sitters “Presents 4 Pets” Program 3Health News:Dallas-based Park Cities Pet Sitter Announces Participation in the 2014 National Association of Professional Pet Sitters “Presents 4 Pets” Program 4
... , , NEW YORK , Aug. ... of Conquer Your Food Addiction (Free Press) will ... ), an online video segment series, on Tuesday, August 4th at ... her own battle with food addiction and weight loss. , , ...
... CARROLLTON, Ga., Aug. 3 , , Physician Quality Reporting ... voluntary program that provides financial incentives to care providers who successfully report on a specified ... Physician Fee Schedule , , , , ... Services (CMS) , , , , ...
... PA, 3 August 2009 A new class of antibody ... of eye diseases in children, but specialists need to be ... an editorial in the August Journal of AAPOS ... Dr. Robert L. Avery of Santa Barbara, Calif., discusses ...
... are often not capable of changing their behavior. ... MRI technology, scientists at Heidelberg University Hospital have ... metabolism that explain this disturbed eating behavior. ... and General Internal Medicine at Heidelberg University Hospital ...
... , , , ... Samplify Systems, Inc., a next generation mixed-signal semiconductor company, today ... algorithm for implementation on popular FPGA platforms and its award ... help solve transmission issues faced by high-data bandwidth signal processing ...
... SAO PAULO, Aug. 3 Medial Saude S/A,(BOVESPA: MEDI3) (MEDIAL SAUDE) announces the following webcast: ... Call, When: Friday, August 14, 2009 at 12:00 ... Live over the Internet -- Simply log on to the ... address above., Conference call dial-in phone numbers:, Toll-free ...
Cached Medicine News:Health News:The Caryl Ehrlich Program Discusses Food Addiction on HealthyPlace.com 2Health News:Greenway Medical Technologies' EHR Solution, PrimeSuite, Enables Eligible Professionals to Participate in PQRI Through Integration With Outcome Sciences, a 2009 CMS Qualified PQRI Registry 2Health News:Greenway Medical Technologies' EHR Solution, PrimeSuite, Enables Eligible Professionals to Participate in PQRI Through Integration With Outcome Sciences, a 2009 CMS Qualified PQRI Registry 3Health News:Greenway Medical Technologies' EHR Solution, PrimeSuite, Enables Eligible Professionals to Participate in PQRI Through Integration With Outcome Sciences, a 2009 CMS Qualified PQRI Registry 4Health News:Anti-growth factor drugs raise hope and concern for treatment of children's eye diseases 2Health News:Why anorexic patients cling to their eating disorder 2Health News:Samplify Systems Announces Next Generation Signal-Compression Technology, Prism 3.0 2Health News:Samplify Systems Announces Next Generation Signal-Compression Technology, Prism 3.0 3
Binkhorst, length 35 mm....
Army navy retractor set....
Rigid neck rake retractor, 3 sharp prong....
Rees bayonet forceps, standard, 5-1/2", TC....
Medicine Products: