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Research Results on FluMist Presented at National Association of,Pediatric Nurse Practitioners Conference

ation for children under 12 months of age or for children 12 months to 59 months of age who have a past history of wheezing illness. In children 12 months to 59 months of age without a past history of wheezing, there was a trend (though not statistically significant) in the opposite direction in that there were fewer hospitalizations in children who received FluMist compared to the flu shot. In children 12 months to 59 months of age without a past history of wheezing, the rates of wheezing were not statistically different in children who received FluMist (4.7 percent) compared to the flu shot (4.9 percent).

About FluMist

FluMist is currently indicated for active immunization for the prevention of disease caused by influenza A and B viruses in healthy children and adolescents, 5 to 17 years of age, and healthy adults, 18 to 49 years of age. There are risks associated with all vaccines, including FluMist. As with any vaccine, FluMist does not protect 100 percent of individuals vaccinated and may not protect against viral strains not contained in the vaccine.

Under no circumstances should FluMist be administered as an injection (i.e., parenterally). FluMist is contraindicated in persons with hypersensitivity to any component of the vaccine, including eggs; in children and adolescents receiving aspirin therapy or aspirin-containing therapy; in individuals with a history of Guillain-Barre syndrome; and in individuals with known or suspected immune deficiency. The safety and efficacy of FluMist have not been established in pregnant women or for patients with chronic underlying medical conditions, including asthma or reactive airways disease; the vaccine should not be administered to these patients.

In randomized, placebo-controlled clinical trials of FluMist in its refrigerated and frozen formulations, the most common solicited adverse events in the indicated population (n=11,604) included runny nose/nasal congestion, sore throat, cough, irrita
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